d20:0

Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers. Sphinganine can block protein kinase C activation in some cases but not others.

DL-Erythro sphinganine (d20:0) is a mixture comprising naturally occurring sphinganine (d20:0) and synthetic L-erythro sphinganine (d20:0).

Dextran T200 (MW 200,000) is a polymer of dehydrated glucose with an average molecular weight of 200,000. It has excellent biodegradability and biocompatibility, making it suitable for use in the fields of food, pharmaceuticals, cosmetics, and research.

WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).

Deprodone propionate (RD20000) is a synthetic corticosteroid suitable for inflammation research.

Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1). Crisdesalazine reduces autophagosome formation, axonopathy, and motor neuron degeneration, improving motor function and increasing life span.

DPD 20027 is a bioactive chemical.

Anti-OX2R/CD200R1 Antibody is a human-derived antibody expressed in CHO cells and targets OX2R/CD200R1. The predicted molecular weight (MW) of Anti-OX2R/CD200R1 Antibody is 146.58 kDa. For the isotype control of Anti-OX2R/CD200R1 Antibody, refer to Human IgG4 kappa, Isotype Control.

Anti-MouseCD200Antibody (OX-90) is an IgG2a, κ antibody inhibitor derived from rats, targeting mouse CD200.

Ganglioside GM1, a monosialylated ganglioside and the prototypical ganglioside, contains a single sialic acid residue. C18 Ganglioside GM1 is predominantly located in the brain, especially in the piriform cortex, amygdala nucleus, striatum, and hippocampal CA1 region. The C18 ganglioside GM1 (d20:1/18:0) to (d18:1/18:0) ratio is reduced in the outer molecular layer of the hippocampal dentate gyrus in Alzheimer's disease patients' postmortem tissue. Since this product is naturally sourced, variations in the sphingoid backbone may occur. [Matreya, LLC.]