Home Tools
Log in
Cart

Search Result

Search Results for " chondrocytes "

12

Compounds

Cat No. Product Name Synonyms Targets
T1748 Kartogenin KGN TGF-beta/Smad
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
T9138 Indirubin-3′-oxime Indirubin-3'-monoxime GSK-3 , CDK , JNK
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.
TQ0228 Derazantinib ARQ-087 FGFR
Derazantinib (ARQ-087) (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).
T40795 BNTA Reactive Oxygen Species
BNTA is a potent extracellular matrix (ECM) modulator. In a rat model of arthritis, BNTA modulates arthritis by promoting the synthesis of cartilage structural molecules on chondrocytes through the induction of superoxid...
T2795 Amygdalin Laetrile Others
Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...
T6S1579 Monotropein Monotropeine Others
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...
TN5171 Tricetin Apoptosis , Others , Nrf2
Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ...
T76277L Vosoritide acetate
Vosoritide acetate (BMN 111) is a natriuretic peptide receptor 2 (NPR2) agonist that promotes bone growth by influencing the proliferation and differentiation of chondrocytes [1].
T39531 RAD16-I hydrochloride RAD16-I hydrochloride
RAD16-I hydrochloride is a self-assembling peptide with nanofibrous morphology that provides an optimal microenvironment for the proliferation and differentiation of human mesenchymal stem cells (hMSC) into chondrocytes....
T71525 AB05831
AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis...
T10997 Derazantinib Racemate ARQ-087 Racemate Others
Derazantinib Racemate (ARQ-087 Racemate) is the racemate of Derazantinib. Derazantinib is an orally bioavailable, ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocy...
T83733 TIP39 (human, bovine) TFA Tuberoinfundibular Peptide of 39 Residues
TIP39, a neuropeptide and an agonist for the parathyroid hormone receptor type 2 (PTH2R), effectively increases cAMP levels in COS-7 cells featuring recombinant PTH2R from humans or rats (EC50s = 0.5 and 0.8 nM, respecti...
TargetMol