anxiety disorder

Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.

Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.

TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2 3 nM for OX2 1 receptors).

Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) is a deuterium-labeled Duloxetine hydrochloride.

ZLc-002 is a selective small-molecule inhibitor of nNOS-Capon coupling. ZLc-002 suppresses inflammatory nociception and chemotherapy-induced neuropathic pain. ZLc-002 can be used in anxiety disorder and inflammation research[1] [2] [3].

Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).

AZD6280 is a novel, subtype-selective GABAAα2 3 receptor positive modulators, used for treatment of generalized anxiety disorder.

Troriluzole is an orally active glutamate modulator with anticancer activity.Troriluzole enhances the expression of excitatory amino acid transporters located in glial cells and is used in the study of spinocerebellar ataxia, Alzheimer's disease, and generalized anxiety disorder (GAD).

BTG-1640 is used potentially for the treatment of anxiety and panic disorder.

Eritadenine (Lentinacin) is a mushroom-derived compound that acts on the adenosine P-site in adipocyte plasma membranes, lowering cholesterol levels and altering phospholipid composition in rat models of hyperhomocysteinemia, used in anxiety disorder studies.

Sertraline Free Base is a Selective Serotonin Reuptake Inhibitor (SSRI). It can treat depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder, and panic disorder.

Orvepitant is a potent and selective NK1 antagonist, which may be potentially useful for patients with major depressive disorder (MDD), anxiety and insomnia.

Fluvoxamine acid is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the treatment of obsessive-compulsive disorder (OCD), and is also used to treat major depressive disorder (MDD), and anxiety disorders such as panic disorder and post-traumatic stress disorder (PTSD).

Fasedienol is a neurochemical stimulator of the vomeronasal organ (VON) that alleviates symptoms of premenstrual dysphoric disorder (PMS) and anxiety [1].

Buspirone-d8 HCl (n-butyl-d8) is a deuterated compound of Buspirone HCl. Buspirone HCl has a CAS number of 33386-08-2. Buspirone is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).

Orexin Receptor Modulator-1 is a compound utilized in the study of various conditions including substance addiction, panic disorder, anxiety, post-traumatic stress disorder (PTSD), pain, depression, seasonal affective disorder (SAD), eating disorders, and hypertension [1].

BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.

Trazodone (AF-1161), a 5-HT 2A 2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder.

Gepirone is a selective 5-HT1A agonist that selectively binds to 5-HT1A receptor sites. It is employed as an antidepressant in research studies focused on anxiety and major depressive disorder.

Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).

Duloxetine-d7 is a deuterated compound of Duloxetine. Duloxetine has a CAS number of 116539-59-4. Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.

Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder.

neuropeptide S receptor (NPSR) antagonist