acetylcholine

Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

Acetylcholine perchlorate is the perchlorate salt of acetylcholine. Acetylcholine, an endogenous neurotransmitter at cholinergic synapses, could amplify the action potential of the sarcolemma following by inducing muscle contractions.

Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pilofrin) mimics the parasympathomimetic effect of the endogenous compound acetylcholine. Administered as an ophthalmic solution, this drug stimulates the cholinoceptors in the sphincter muscle of the iris, causing the pupil to constrict.

Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central ner

Acetylcholine-D4 Bromide (Standard) is a reference standard of Acetylcholine-D4 Bromide intended for quantitative analysis, quality control, and related biochemical research applications. Acetylcholine-d4 (bromide) is the deuterated form of Acetylcholine bromide.

Acetylcholine-D4 Chloride (Standard) is a reference standard of Acetylcholine-D4 Chloride intended for quantitative analysis, quality control, and related biochemical research applications. Acetylcholine-d4(chloride) is the deuterated form of Acetylcholine chloride. Acetylcholine chloride (ACh chloride) functions as a neurotransmitter and is a potent cholinergic agonist. It modulates dopaminergic (DAergic) neuron activity by stimulating nicotinic acetylcholine receptors (nAChRs). Additionally, Acetylcholine chloride inhibits the aggregation of p53 mutant peptides in vitro.

Acetylcholine-D9 Chloride (Standard) is a reference standard of Acetylcholine-D9 Chloride intended for quantitative analysis, quality control, and related biochemical research applications. Acetylcholine-d9 (chloride) is the deuterated form of Acetylcholine chloride. Acetylcholine chloride (ACh chloride) serves as a neurotransmitter and functions as a potent cholinergic agonist. It modulates dopaminergic (DAergic) neuronal activity by stimulating nicotinic acetylcholine receptors (nAChRs) and inhibits the aggregation of p53 mutant peptides in vitro.

Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.

Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with anticholinergic properties similar to atropine. Upon ocular administration, it binds to and blocks muscarinic receptors in the sphincter and ciliary muscles, inhibiting cholinergic responses and causing pupil dilation and ciliary muscle paralysis. Tropicamide is used as a diagnostic agent to induce short-duration mydriasis and cycloplegia.

Arecoline hydrobromide (Arecoline HBr) is a muscarinic acetylcholine receptor agonist.

Dibenamine hydrochloride is a competitive and irreversible blocker of the β-adrenergic receptor.

DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).

The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.

TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.

VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).

Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of the nicotinic acetylcholine receptor (nAChR) with a Ki of 16.7 nM.

Ambutonium bromide is an antagonist of acetylcholine.

Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating release of acetylcholine and other neurotransmitters.Linopirdine is a putative cognition-enhancing drug that increases acetylcholine release in rat brain tissue.

Hemicholinium 3 is a potent and selective choline uptake blocker.

VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.

RHC 80267 (U-57908) is a selective inhibitor of DAGL, with an IC50 of 4 μM in canine platelets.

Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.

suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.

Acetylcholine, a quaternary ammonium neurotransmitter, is used in biochemical research to study signal transduction in central/peripheral nervous systems.