delay — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T77416	Opicinumab	BIIB033	Others
	Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis.		Others
T61864	Melengestrol acetate		Progesterone Receptor
	Melengestrol acetate is a derivative of progesterone and acts as a corticosteroid hormone. Melengestrol acetate promotes endometrial proliferation delay of menstrual activity and pregnancy maintenance.		Progesterone Receptor
T2S0842	Scutellarin methyl ester	Scutellarin methylester	Others
	Scutellarin methyl ester has the effect of improving sleep, such as prolonging sleep time, increasing the incidence of sleep, shortening sleep latency, which also helps to delay aging process.		Others
T6939	PFI-3	PFI 3	Epigenetic Reader Domain
	PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.		Epigenetic Reader Domain
T5231	2-Methylsuccinic acid	Pyrotartaric Acid,Methylbutanedioic acid	Others , Endogenous Metabolite
	2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical mea...		Others , Endogenous Metabolite
T1458	Epalrestat	ONO2235	Reductase
	Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particul...		Reductase
T10215	AAPK-25		Apoptosis , PLK , Aurora Kinase
	AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in prometaphase, followed by a surge in apoptosis. AAPK-25 targets Aurora-A/-B/-C with ...		Apoptosis , PLK , Aurora Kinase
T3864	Erianin		BCL , Antibacterial
	Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metaboli...		BCL , Antibacterial
TN1594	DL-Syringaresinol	(±)-Syringaresinol	Antioxidant , Antifungal
	DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...		Antioxidant , Antifungal
TMS1461	Qingyangshengenin B	Otophylloside B	Beta Amyloid
	Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...		Beta Amyloid
T4716	Pyrrole-2-carboxylic acid	2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite
	Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela...		Endogenous Metabolite
T77697	BML-278	BML278,BML 278	Sirtuin , Histone Methyltransferase
	BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 ind...		Sirtuin , Histone Methyltransferase
T2170	SKF-96365 hydrochloride	SKF96365	Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy
	SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha...
T4776	Glycerol	Glycerin	Endogenous Metabolite
	Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...		Endogenous Metabolite
TN4173	Guajadial C		Topoisomerase
	Guajadial C acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. It shows cytotoxicity against five human cancer cell lines.		Topoisomerase
T31280	Decaborane, ethyl-,	Ethyldecaborane,Decaborane, ethyl-,Ethyldekaboran
	Decaborane, ethyl-, Nonaborane and decaborane cluster anions can enhance the ignition delay in hypergolic ionic liquids and induce hypergolicity in molecular solvents.
TN5348	Guajadial F
	Guajadial F acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. Guajadial F shows cytotoxicity against five human cancer cell lines.
T73413	Cadein1
	Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.
T21921	Valeroyl Salicylate	2-Valeryloxybenzoic acid	Others
	Valeroyl Salicylate (2-Valeryloxybenzoic acid) has anti-inflammatory properties that extend lifespan, delay the age-related decline in spontaneous activity, and improve stress tolerance.		Others