2'deoxyuridine

2-Deoxyuridine is a Nucleoside Derivative - 2-Deoxy uridine.

5-Formyl-2'-deoxyuridine, an effective inhibitor of herpes simplex virus type 1 or 2 (HSV-1, HSV-2) and vaccinia virus, was converted to the oxime and dithiolane derivatives.

N3-Methyl-2'-deoxyuridine is a Nucleoside Derivative - N-Methylated nucleoside.

5-(2-Hyroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template.

2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor exhibiting anti-cancer activity.

5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoid malignancies. Its anticancer effects are primarily through the inhibition of DNA synthesis and the induction of apoptosis, among other mechanisms [1].

Rp-2'-Deoxyuridine-5'-O-(1-thiotriphosphate) (Rp-dUTP-α-S), a sulfur-containing nucleotide isomer and purinergic P2Y2 receptor agonist, preferentially promotes inositol phosphate accumulation in 1321N1 astrocytoma cells with P2Y2 receptors (EC50 = 12.5 µM) compared to those expressing P2Y4 receptors at a concentration of 10 µM.

2'-Chloro-2'-deoxyuridine is a Halo-nucleoside.

5-Bromo-2'-fluoro-2'-deoxyuridine is a Nucleoside, fluoro-modified nucleoside, halo-nucleoside.

5'-O-DMTr-5-Iodo-2'-deoxyuridine is a Halo-nucleoside.

2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.

5-Amino-2'-deoxyuridine hydrochloride is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Amino nucleoside.

5-(2-Hyroxyethyl)-2'-deoxyuridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside.

5'-O-Triphenylmethyl-2'-deoxyuridine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

2-Deoxy-2'-deoxyuridine is a Nucleoside Derivative - 2-Deoxy uridine.

3'-O-Acetyl-2'-deoxyuridine (Catalog No. TNU1634, CAS No. 23197-88-8) is a valuable organic compound for life sciences research.

Nucleoside Derivatives - 2'-Modified nucleoside; Halo-nucleoside

Nucleoside Derivatives - 3'-Modified nucleoside, Azido-nucleosides

Nucleoside Derivatives - Azido-nucleosides, 5-Modified pyrimidine nucleosides

Nucleoside Derivatives –3'-Deoxy nucleosides;Nucleoside Phosphoramidites

2'-Deoxyuridine (2-deoxyuridine). An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.

Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.