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TOPK

T-LAK cell-originated protein kinase (TOPK) is a MAPKK-like kinase which plays a role in cell cycle regulation and mitotic progression. As a consequence, TOPK expression is minimal in differentiated cells, although its overexpression is a pathophysiological feature of many tumours. Hence, TOPK has garnered interest as a cancer-specific biomarker and biochemical target with the potential to enhance cancer therapy whilst causing minimal harm to normal tissues.
Cat. No. Product name CAS No. Purity Chemical Structure
T4134L OTS514 1338540-63-8 98%
OTS514 is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell l...
T1756L Ilaprazole 172152-36-2 98%
Ilaprazole is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that...
T1756 Ilaprazole sodium 172152-50-0 98%
Ilaprazole, a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environ...
T4134 OTS514 hydrochloride 2319647-76-0 98%
OTS514 is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).
T15481 HI-TOPK-032 487020-03-1 98%
HI-TOPK-032 is an effective and specific inhibitor of TOPK.
T4135 OTS964 hydrochloride 1338545-07-5 98%
OTS964 is a potent and selective TOPK inhibitor with potential anticancer activity.
T0199 Cephradine 38821-53-3 98%
Cephradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
OTS514
T4134L
OTS514 is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell l...
Ilaprazole
T1756L
Ilaprazole is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that...
Ilaprazole sodium
T1756
Ilaprazole, a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environ...
OTS514 hydrochloride
T4134
OTS514 is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).
HI-TOPK-032
T15481
HI-TOPK-032 is an effective and specific inhibitor of TOPK.
OTS964 hydrochloride
T4135
OTS964 is a potent and selective TOPK inhibitor with potential anticancer activity.
Cephradine
T0199
Cephradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.