vitamin b12

Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 (Cobalamin) deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.

Biotin-Vitamin B12, a biotinylated form of Vitamin B12, is essential for normal brain and nervous system functions as well as blood formation [1].

Vitamin B12a hydrochloride (Hydroxocobalamin hydrochloride) is the natural active form of vitamin B12 and is an essential water-soluble vitamin.It is commonly used as a cyanide detoxifier and nutritional supplement, and can be administered by injection, inhalation, or orally.

Vitamin B12-d6 is a deuterated compound of Vitamin B12.Vitamin B12 has a CAS number of 68-19-9.

Vitamin B12-13C7 is the 13C labeled compound of Vitamin B12. Vitamin B12 has a CAS number of 68-19-9.

Vitamin B12 (Standard) is the standard substance of Vitamin B12, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 (Cobalamin) deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.

Vitamin B12-[13C7] (Standard) is a reference standard of Vitamin B12-[13C7] intended for quantitative analysis, quality control, and related biochemical research applications.

Vitamin B12 (Cyanocobalamin) hydrate plays a pivotal role in maintaining the normal functioning of the brain, the nervous system, and blood formation. This compound is beneficial in various inflammatory diseases and provides protection against pathologies related to oxidative stress.

Methylcobalamin (Brassinolide) is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.

Hydroxocobalamin (Vitamin B12a) is a naturally occurring, injectable form of vitamin B12 used as a dietary supplement to treat B12 deficiency, including pernicious anemia, and is known for its favorable adverse effect profile [1] [2].

Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced only by certain bacteria and archaea. It is a cofactor for various enzymes including mutases, eliminases, aminomutases, and a reductase.

2'-Deoxyuridine (2-deoxyuridine). An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.

Hydroxocobalamin acetate is used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia. Hydroxocobalamin, an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, is approved by the US Food and Drug Administration for the treatment of cyanide toxicity.

Succinylacetone pyrrole exhibits a significant inhibitory effect on the biosynthesis of vitamin B12.

Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across th

Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of certain oral contraceptives to ens

Methylmalonyl coenzyme A (methylmalonyl-CoA) is an intermediate in multiple metabolic pathways in bacteria and eukaryotes.1,2,3It is an intermediate in carbon assimilation in certain bacteria and carbon fixation in plants.1,2Methylmalonyl-CoA is converted to succinyl-CoA by methylmalonyl-CoA mutase with vitamin B12as a coenzyme.3A deficiency in vitamin B12leads to a build-up of methylmalonyl-CoA.4 1.Anthony, C.How half a century of research was required to understand bacterial growth on C1 and C2 compounds; the story of the serine cycle and the ethylmalonyl-CoA pathwaySci. Prog.94(Pt 2)109-137(2011) 2.Tabita, F.R.The hydroxypropionate pathway of CO2 fixation: Fait accompliProc. Natl. Acad. Sci. U.S.A.106(50)21015-21016(2009) 3.Medicine, I.o.Vitamin B12Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline306-356(1998) 4.Cardinale, G.J., Carty, T.J., and Abeles, R.H.Effect of methylmalonyl coenzyme A, a metabolite which accumulates in vitamin B12 deficiency, on fatty acid synthesisJ. Biol. Chem.245(15)3771-3775(1970)

Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodium salt) is involved in a variety of metabolic reactions in living organisms, and plays an important role in the body.Succinyl-Coenzyme A (sodium salt) is involved in heme synthesis. Succinyl-Coenzyme A (sodium salt) is involved in the synthesis of hemoglobin and is used in the study of metabolic, neurological, and hematological disorders caused by nutritional vitamin B12 deficiency, which results in a deficiency in Succinyl-Coenzyme A synthesis.

Methylcobalamin-13C-d3 is the 13C and deuterated compound of Methylcobalamin. Methylcobalamin has a CAS number of 13422-55-4. Methylcobalamin is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.

Levocarnitine propionate hydrochloride (Standard) is a natural acylcarnitine that plays a role in fatty acid metabolism and is a biomarker for vitamin B12 deficiency, used for quantitative detection, metabolic pathway research and disease diagnostics.

Succinyl-Coenzyme A sodium salt (Standard) is a reference standard for research and analysis in studies involving Succinyl-Coenzyme A sodium salt. Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodium salt) is involved in a variety of metabolic reactions in living organisms, and plays an important role in the body.Succinyl-Coenzyme A (sodium salt) is involved in heme synthesis. Succinyl-Coenzyme A (sodium salt) is involved in the synthesis of hemoglobin and is used in the study of metabolic, neurological, and hematological disorders caused by nutritional vitamin B12 deficiency, which results in a deficiency in Succinyl-Coenzyme A synthesis.

Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a metabolic product derived from the breakdown of odd-chain fatty acids, cholesterol, and certain amino acids, such as valine, isoleucine, methionine, and threonine. It is enzymatically converted into succinyl-CoA through the action of methylmalonyl-CoA mutase (MCM) utilizing coenzyme vitamin B12.

Methylmalonyl-CoA tetralithium, also known as Methylmalonyl coenzyme A, serves as a metabolic byproduct derived from the breakdown of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. It is converted into succinyl-CoA through the enzymatic activity of methylmalonyl-CoA mutase (MCM) in the presence of the coenzyme vitamin B12 [1].

Nervon, a crystalline cerebroside, is utilized in the investigation of peripheral neuropathy and megaloblastic anemia caused by Vitamin B12 deficiency.