Search Result

Search Results for " viability "

Targets

176

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T16104	ML-9		Myosin , Akt
	ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction ...		Myosin , Akt
T6878	LJI308		S6 Kinase
	LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.		S6 Kinase
T8308	NL-1		Mitochondrial Metabolism , Autophagy
	NL-1 is a mitoNEET inhibitor with antileukemic effect.		Mitochondrial Metabolism , Autophagy
T5104	BTSA1		Apoptosis , BCL
	BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.		Apoptosis , BCL
T9662	SRI 37892		Wnt/beta-catenin
	SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.		Wnt/beta-catenin
T5627	Methoxychlor		Others
	Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.		Others
T11940	Malic enzyme inhibitor ME1	ME1	Others
	Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.		Others
T68051	Delequamine	RS 15385-197	Adrenergic Receptor
	Delequamine (RS 15385-197) is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.		Adrenergic Receptor
T6682	STF-118804	STF 118804,STF118804	Apoptosis , NAMPT
	STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.		Apoptosis , NAMPT
T12896L	Shepherdin 79-87 acetate	Shepherdin 79-87 acetate (861224-28-4 free base)	HSP , Survivin
	Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.		HSP , Survivin
T14017	2-NBDG		Others
	2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability.		Others
T7366	NGI-1	ML414	Virus Protease
	NGI-1 (ML414) is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability.		Virus Protease
T16040	Mepazine	Pecazine	Apoptosis , MALT
	Mepazine (Pecazine) is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability.		Apoptosis , MALT
T9776	TRPM4 inhibitor 8		TRP/TRPV Channel
	TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.		TRP/TRPV Channel
T9955	EX-A5758		NOS
	EX-A5758 is a novel putative small molecule nNOS-NOS1AP inhibitor, suppressing inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability.		NOS
T5580	1-Naphthaleneacetic acid potassium salt	α-Naphthaleneacetic acid,Potassium alpha-naphthylacetate,Potassium 1-Naphthaleneacetate,1-NAA Potassium Salt	Phospholipase
	1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) is used as a plant Growth Regulator that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fu...		Phospholipase
T77660	TINK-IN-1		Wnt/beta-catenin
	TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.		Wnt/beta-catenin
T8850	Sbp-7455		Autophagy
	SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.		Autophagy
T6916	OICR-9429	OICR 9429	Histone Methyltransferase , JAK
	OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro.		Histone Methyltransferase , JAK
T27064	CP-312	CP312,Cardioprotectant 312	Reactive Oxygen Species , Autophagy
	CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1...		Reactive Oxygen Species , Autophagy
T28543	RK-9123016	RK9123016,RK 9123016	Sirtuin
	RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer ce...		Sirtuin
T22429	SR18662		DNA/RNA Synthesis
	SR18662, an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM, reduces the viability of multiple colorectal cancer cell lines and induces apoptosis.		DNA/RNA Synthesis
T22821	GSK J5	GSK-J5,GSKJ5	Histone Demethylase
	GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.GSK J5 increases the mortality rate of schistos...		Histone Demethylase
T1937	Spautin-1	Spautin 1	Apoptosis , DUB , Autophagy
	Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM.		Apoptosis , DUB , Autophagy
T6911	NSC-87877 disodium	NSC87877	Apoptosis , Phosphatase
	NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduce...		Apoptosis , Phosphatase
T8421	TED-347		YAP
	TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.		YAP
T1642	Lenalidomide	CC-5013	Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
	Lenalidomide (CC-5013) is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.		Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
T9949	NSC 370284		STAT
	NSC 370284 is a small molecule that directly binds to and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.		STAT
T18894	5(6)-CFDA	CFDA,5-(6)-Carboxyfluorescein diacetate	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activities, which is required to activate its fluorescence, and cell-m...		Others
T72968	ZINC00640089		Akt
	ZINC00640089 is a selective lipid carrier protein-2 (LCN2) inhibitor. ZINC00640089 inhibited cell proliferation and cell viability, and reduced AKT phosphorylation in SUM149 cells. ZINC00640089 can be used to study infla...		Akt
T83653	SACLAC		Apoptosis , Caspase
	SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity that decreases AML cell viability, inhibits AML cell proliferation, increases AML cell death, and induces apoptosis of AML cells, and is used...		Apoptosis , Caspase
T13983	0990CL		cAMP , Others
	0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP regulation. In the cell model, low concentration of 0990CL cou...		cAMP , Others
T37518	Diphenyl disulfide	Phenyl disulfide	Apoptosis , BCL , Endogenous Metabolite
	Diphenyl disulfide (Phenyl disulfide) shows anticancer activity in breast cancer cell lines.Diphenyl disulfide induces and enhances apoptosis in breast cancer cells through Bax protein hydrolysis activation and concomita...		Apoptosis , BCL , Endogenous Metabolite
T28773	SI-2	SI2,EPH 116,EPH116,EPH-116	Others
	SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast can...		Others
T9105	NF-κB-IN-1	1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-	IκB/IKK , NF-κB
	NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir...		IκB/IKK , NF-κB
T2331	Solithromycin	OP-1068,CEM-101	Antibacterial , Antibiotic
	Solithromycin (OP-1068) is an orally bioavailable antimicrobial agent that inhibits cell viability, protein synthesis, and growth rate of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus aureus, and Haemop...		Antibacterial , Antibiotic
T36493	CMLD-2		Apoptosis , HuR
	CMLD-2 is an inhibitor of HuR-ARE interaction (Ki: 350 nM) that competitively binds HuR protein and disrupts its interaction with adenine element-rich (ARE) mRNA targets.CMLD-2 induces apoptosis and exhibits antitumor ef...		Apoptosis , HuR
T36141	Boscalid		Mitochondrial Metabolism
	Boscalid is a broad-spectrum carboxamide fungicide that inhibits fungal respiration by binding to the ubiquinone site of mitochondrial complex II/succinate dehydrogenase.1It suppresses mycelial growth ofS. minorby 87 to ...		Mitochondrial Metabolism
T7650L	Resazurin	Resazoin,Diazoresorcinol,Azoresorcin,Resazurine
	Resazurin is used as an oxidation-reduction indicator in cell viability.
T31696	EthD-1	EthD1,Ethidium Homodimer-1
	EthD-1 is a cell-impermeant viability indicator. It acts as a high-affinity nucleic acid stain.
T28138	NCDM-32B	NCDM 32B,NCDM32B
	NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.
T33219	MB725	MB 725,MB-725
	MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.
T34695	Spiclomazine HCl	APY-606,Diceplon,Disepron,APY606,Spiclomazine Hydrochloride
	Spiclomazine HCl induced apoptosis in pancreatic cancer cells, which was generally related to cell viability, migration, and invasion.
T19771	SXT1596	NSC-65667,SXT-1596,NSC 65667,SXT 1596,NSC65667
	SXT1596 is a novel SS18-SSX/TLE1 interaction inhibitor. SXT1596 reduces cell viability and reactivates EGR1 expression in synovial sarcoma.
T24423	LY5	LY 5,LY-5
	LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.
T36326	Calcein Orange™ Diacetate
	Calcein Orange Diacetate is a fluorogenic dye that is used to assess cell viability. It is hydrolyzed to the fluorescent probe Calcein Orange . Calcein Orange is retained by living cells and displays excitation/emissi...
T18931	Calcein-AM	Calcein acetoxymethyl ester	Others
	Calcein-AM is a cell-permeable fluorescent dye used for the determination of cell viability.		Others
T28079	MMV665852	MMV-665852,MMV 665852
	MMV665852, an antischistosomal agent, has been shown to inhibit worm viability in vitro and reduce worm burden in S. mansoni-infected mice.
T71413	U 26384
	U 26384 is a phospholipase A2 inhibitor reduces the severity of cell injury, but does not maintain cell viability in cultured human astroglial cell line UC-11MG during ATP depletion.
T71620	IBAP-II
	iBAP-II represses neuroendocrine lineage-specific ASCL1/MYCL/E2F signaling in SCLC cell lines, and dramatically inhibits SCLC cell viability and tumor growth in vivo.

Compounds

Target: Mitochondrial Metabolism, Autophagy

BTSA1

T5104

Synonym:

Target: Apoptosis, BCL

SRI 37892

T9662

Synonym:

Target: Wnt/beta-catenin

Malic enzyme inhibitor ME1

Synonym: RS 15385-197

Target: Adrenergic Receptor

STF-118804

T6682

Synonym: STF 118804,STF118804

Target: Apoptosis, NAMPT

Shepherdin 79-87 acetate

T12896L

Synonym: Shepherdin 79-87 acetate (861224-28-4 free base)

Target: HSP, Survivin

Target: Virus Protease

Mepazine

T16040

Synonym: Pecazine

Target: Apoptosis, MALT

TRPM4 inhibitor 8

T9776

Synonym:

Target: TRP/TRPV Channel

1-Naphthaleneacetic acid potassium salt

T5580

Synonym: α-Naphthaleneacetic acid,Potassium alpha-naphthylacetate,Potassium 1-Naphthaleneacetate,1-NAA Potassium Salt

Target: Phospholipase

TINK-IN-1

T77660

Synonym:

Target: Wnt/beta-catenin

Target: Histone Methyltransferase, JAK

CP-312

T27064

Synonym: CP312,Cardioprotectant 312

Target: Reactive Oxygen Species, Autophagy

RK-9123016

T28543

Synonym: RK9123016,RK 9123016

Target: DNA/RNA Synthesis

GSK J5

T22821

Synonym: GSK-J5,GSKJ5

Target: Histone Demethylase

Spautin-1

T1937

Synonym: Spautin 1

Target: Apoptosis, DUB, Autophagy

NSC-87877 disodium

T6911

Synonym: NSC87877

Target: Apoptosis, Phosphatase

Target: Apoptosis, TNF, Ligand for E3 Ligase, Molecular Glues

Synonym: CFDA,5-(6)-Carboxyfluorescein diacetate

Target: Apoptosis, Caspase

Synonym: Phenyl disulfide

Target: Apoptosis, BCL, Endogenous Metabolite

SI-2

T28773

Synonym: SI2,EPH 116,EPH116,EPH-116

Target: Others

NF-κB-IN-1

T9105

Synonym: 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-

Target: IκB/IKK, NF-κB

Solithromycin

T2331

Synonym: OP-1068,CEM-101

Target: Antibacterial, Antibiotic

CMLD-2

T36493

Synonym:

Target: Apoptosis, HuR

Boscalid

T36141

Synonym:

Target: Mitochondrial Metabolism

Resazurin

T7650L

Synonym: Resazoin,Diazoresorcinol,Azoresorcin,Resazurine

Target:

EthD-1

T31696

Synonym: EthD1,Ethidium Homodimer-1

Target:

NCDM-32B

T28138

Synonym: NCDM 32B,NCDM32B

Target:

MB725

T33219

Synonym: MB 725,MB-725

Target:

Spiclomazine HCl

T34695

Synonym: APY-606,Diceplon,Disepron,APY606,Spiclomazine Hydrochloride

Target:

SXT1596

T19771

Synonym: NSC-65667,SXT-1596,NSC 65667,SXT 1596,NSC65667

Calcein Orange™ Diacetate

Synonym: Calcein acetoxymethyl ester

Target: Others

MMV665852

T28079

Synonym: MMV-665852,MMV 665852

Cat No.	Product Name	Synonyms	Targets
T7982	3,6-Dihydroxyflavone		Others
	3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.		Others
TN1465	Cannabigerol		NOS , 5-HT Receptor , ROS
	Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur...		NOS , 5-HT Receptor , ROS
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
TN3694	Coniferaldehyde		NOS , COX , Nrf2 , PKC , Autophagy
	Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni. Coniferaldehyde exerts anti-inflammatory properties by inducing heme oxygenase-1(HO-1).		NOS , COX , Nrf2 , PKC , Autophagy
TN1425	Bacoside A3		ATPase , ROS , P-gp
	Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.		ATPase , ROS , P-gp
T2S1396	3-O-Acetyloleanolic acid		Apoptosis
	3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G1 apoptotic cell populations.		Apoptosis
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T3S1873	Talatisamine		Potassium Channel
	1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...		Potassium Channel
T4S0779	D-tetrahydropalmatine		Others , Dopamine Receptor
	D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re...		Others , Dopamine Receptor
T6S1780	Protosappanin B	Q-100961,FT-0689654	Apoptosis
	1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, vi...		Apoptosis
T2897	(Rac)-Shikonin	(±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid	Others
	(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...		Others
T36473	Trans-Nerolidol
	trans-Nerolidol is a sesquiterpene that has been found in various plants, includingC. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties.1,2,3,4In...
TWO2727	Propane-1,2,3-triyl tripalmitate	Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate	Others , Endogenous Metabolite
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ...		Others , Endogenous Metabolite
T2860	Vanillyl Alcohol	4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol	Apoptosis , Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ...		Apoptosis , Others
T6S1653	Albiflorin	Alibiflorin	Reactive Oxygen Species
	1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...		Reactive Oxygen Species
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
TN2496	1,4-Anthraquinone		Others
	1,4-Anthraquinone is an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar ...		Others
T4958	(-)-Alkannin	Alkannin,Shikonin	Apoptosis , PI3K
	(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a...		Apoptosis , PI3K
T0122	Bergenin	Cuscutin,Bengenin	Apoptosis , IL Receptor , Virus Protease , TNF , NF-κB , Antibacterial , NOD , Autophagy , Antifungal
	Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T40834	5-Hydroxymethyl-2'-deoxycytidine	5hmdC	PARP
	5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxy...		PARP
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T4S1615	Sanggenon C	Sanggenone C	NF-κB
	1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO pro...		NF-κB
T5S0053	Coptisine	Coptisin	Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...		Indoleamine 2,3-Dioxygenase (IDO)
TN1493	Chrysosplenol D		IL Receptor , NF-κB , JNK
	Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.		IL Receptor , NF-κB , JNK
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
TN1156	(-)-Curine		p53
	(-)-Curine can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status.		p53
T38495	Gypenoside LXXV
	Gypenoside LXXV, derived from Gynostemma pentaphyllum, is a deglycosylated form of ginsenoside Rb1. This compound effectively decreases cancer cell viability and exhibits potent anti-cancer properties.
TN1407	Artocarpin		IL Receptor , TNF , COX
	Artocarpin has anti- bactericidal effect, can reduce the viability of pneumococci by a factor of >1000, without obvious harm to lung epithelial cells.		IL Receptor , TNF , COX
TN3737	Cycloartane-3,24,25-triol		ATPase
	Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the viability of PC-3 and DU145 cell lines with IC50 values of 2.226 ± 0.28 μM and 1.67 ± 0.18 μM respec...		ATPase
T37444	Aranorosin
	Aranorosin is a fungal metabolite originally isolated from P. roseus. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viabilit...
TN2501	1,5,6-Trihydroxy-3-methoxyxanthone	芒果	ROS
	1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.		ROS
TN3742	Cycloeucalenol		Others
	Cycloeucalenol produces mild cardiotonic effects. Cycloeucalenol and its regio-isomer were present in a ratio of 1.04:1, a dose-dependent decrease in cell viability was observed.		Others
TN4699	Ohchinin		Others
	Ohchinin exhibits potent inhibitory activities with 26 - 66% reduction of melanin content at 100 μm concentration with almost no or low toxicity to the B16 melanoma cells (70 - 99% cell viability at 100 μm).		Others
T72735	Coleon-U-quinone
	Coleon-U-quinone, a potent P-gp (P-glycoprotein) inhibitor, effectively reduces the viability of cancer cells and increases the sensitivity of multidrug-resistant cancer cells to Doxorubicin [1].
T13922	Thevetiaflavone	2-Genistein-5-methyl ether,Apigenin-5-methyl ether	BCL , Caspase
	Thevetiaflavone (2-Genistein-5-methyl ether) is a natural flavonoid from Wikstroemia indica that inhibits the leakage of lactate dehydrogenase from the cytoplasm and increases cell viability.		BCL , Caspase
T79982	2'-epi-2'-O-Acetylthevetin B	GHSC-74	Apoptosis
	2'-Epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside extractable from Cerbera manghas L. seeds, diminishes cell viability, triggers apoptosis, and disrupts mitochondrial membrane potential in HepG2 cells [1].		Apoptosis
T72459	3-Oxo-hop-22(29)-ene
	3-Oxo-hop-22(29)-ene, a compound acting as a yeast α-glucosidase inhibitor, demonstrates moderate efficacy against T. cruzi and L. mexicana viability, and exhibits marginal anti-inflammatory activity.
TN1009	Epimagnolin B		NF-κB , NO Synthase , Prostaglandin Receptor
	Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear transl...		NF-κB , NO Synthase , Prostaglandin Receptor
TN4592	Murrangatin		IL Receptor , TNF , COX , Prostaglandin Receptor
	Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity ag...		IL Receptor , TNF , COX , Prostaglandin Receptor
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re...
T35770	Cylindrospermopsin
	Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of ...
T66078	Cardamonin
	Cardamonin, a chalcone extracted from cardamom spice with anti-inflammatory and anti-tumor activities. Cardamonin decreased viability of NPC(Nasopharyngeal carcinoma ) cells in a concentration-dependent manner. The IC50 ...
TN3323	Monomethyl lithospermate	Lithospermic acid monomethyl ester	Akt , PI3K
	Monomethyl lithospermate (Lithospermic acid monomethyl ester) has potential antiviral activity, alleviating ischemic stroke injury in vivo in middle cerebral artery occlusion mice by activating PI5K/Akt signaling and pro...		Akt , PI3K
T37291	Lyso-Globotriaosylceramide (d18:1)	Lyso-Globotriaosylceramide (d18:1)
	Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also ...

Natural Products

Target: NOS, 5-HT Receptor, ROS

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Coniferaldehyde

TN3694

Synonym:

Target: NOS, COX, Nrf2, PKC, Autophagy

Bacoside A3

TN1425

Synonym:

Target: ATPase, ROS, P-gp

3-O-Acetyloleanolic acid

Synonym: Citro,Citretten

Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic

Talatisamine

T3S1873

Synonym:

Target: Potassium Channel

D-tetrahydropalmatine

T4S0779

Synonym:

Target: Others, Dopamine Receptor

Protosappanin B

T6S1780

Synonym: Q-100961,FT-0689654

Target: Apoptosis

(Rac)-Shikonin

T2897

Synonym: (±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid

Propane-1,2,3-triyl tripalmitate

TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate

Target: Others, Endogenous Metabolite

Vanillyl Alcohol

T2860

Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol

Target: Apoptosis, Others

Albiflorin

T6S1653

Synonym: Alibiflorin

Target: Reactive Oxygen Species

Arnicolide D

TN1405

Synonym:

Target: Akt, Caspase, PI3K, STAT, mTOR

Synonym: Alkannin,Shikonin

Target: Apoptosis, PI3K

Bergenin

T0122

Synonym: Cuscutin,Bengenin

Target: Apoptosis, IL Receptor, Virus Protease, TNF, NF-κB, Antibacterial, NOD, Autophagy, Antifungal

5-Hydroxymethyl-2'-deoxycytidine

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid

Target: Others, HIV Protease

Sanggenon C

T4S1615

Synonym: Sanggenone C

Target: Indoleamine 2,3-Dioxygenase (IDO)

Chrysosplenol D

TN1493

Synonym:

Target: IL Receptor, NF-κB, JNK

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Target: IL Receptor, TNF, COX

Cycloartane-3,24,25-triol

1,5,6-Trihydroxy-3-methoxyxanthone

Synonym: 2-Genistein-5-methyl ether,Apigenin-5-methyl ether

Target: BCL, Caspase

2'-epi-2'-O-Acetylthevetin B

Target: NF-κB, NO Synthase, Prostaglandin Receptor

Murrangatin

TN4592

Synonym:

Target: IL Receptor, TNF, COX, Prostaglandin Receptor

Monomethyl lithospermate

TN3323

Synonym: Lithospermic acid monomethyl ester

Target: Akt, PI3K

Lyso-Globotriaosylceramide (d18:1)

T37291

Synonym: Lyso-Globotriaosylceramide (d18:1)

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-00986	IL-34 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocyt...
TMPY-05296	IL-34 Protein, Human, Recombinant (His)	Human	CHO
	IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocyt...
TMPY-03662	GM-CSF/CSF2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-00750	GM-CSF/CSF2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-03858	GM-CSF/CSF2 Protein, Human, Recombinant	Human	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-03713	GM-CSF/CSF2 Protein, Rat, Recombinant (His)	Rat	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-04114	GM-CSF/CSF2 Protein, Mouse, Recombinant	Mouse	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPH-01656	MAGEA12 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines.
TMPK-00306	TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated	Human	HEK293
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPH-03123	Rhodopsin Protein, Pig, Recombinant (GST & His)	Sus scrofa (Pig)	E. coli
	Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t...
TMPH-00299	Rhodopsin Protein, Bovine, Recombinant (His)	Bovine	in vitro E. coli expression system
	Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t...
TMPH-03124	Rhodopsin Protein, Pig, Recombinant (GST)	Sus scrofa (Pig)	E. coli
	Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t...
TMPH-03445	GSP1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	Yeast
	GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Essential for cell viability. By analogy with Ras, Ran may be activated when GTP i...
TMPH-00300	Rhodopsin Protein, Bovine, Recombinant (His & KSI)	Bovine	E. coli
	Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t...
TMPH-03728	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc)	ZEBOV	Baculovirus
	Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD...
TMPK-00030	LAIR2 Protein, Human, Recombinant (Avi & His)	Human	HEK293
	The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human...
TMPH-03727	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His)	ZEBOV	E. coli
	Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD...
TMPY-00607	PSMB6 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	PSMB6 subunit belongs to the 20S proteasomal subunit family, which plays an importance role in the antigen presentation by MHC class I molecular. Proteasome subunit beta type 6 (PSMB6) is a member of 20S proteasomal subu...
TMPH-01657	MAGEA3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a as repressor of autophagy. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubi...
TMPY-03047	Stathmin 1 Protein, Human, Recombinant (His)	Human	E. coli
	Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and ...
TMPY-00261	Meprin beta Protein, Human, Recombinant (His)	Human	HEK293
	MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the me...
TMPY-01593	Cyclophilin A Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein that belongs to the cyclophilin-type PPIase family and PPIase...
TMPY-06821	THRB Protein, Human, Recombinant (His)	Human	E. coli
	Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
TMPH-02910	Somatostatin Protein, Mouse, Recombinant (His & KSI)	Mouse	E. coli
	Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhib...
TMPY-04446	AKT3 Protein, Mouse, Recombinant (aa 106-479)	Mouse	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
TMPY-04023	BCCIP Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	BCCIP was originally identified as a BRCA2 and CDKN1A interacting protein that has been implicated in maintenance of genomic stability, cell cycle regulation, and microtubule dynamics. The secondary genetic alternations ...
TMPY-00578	BCCIP Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	BCCIP was originally identified as a BRCA2 and CDKN1A interacting protein that has been implicated in maintenance of genomic stability, cell cycle regulation, and microtubule dynamics. The secondary genetic alternations ...
TMPY-02177	Cyclophilin A Protein, Human, Recombinant (His)	Human	E. coli
	Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein that belongs to the cyclophilin-type PPIase family and PPIase...
TMPY-04430	P38 gamma/MAPK12 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04429	P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04553	AKT3 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
TMPY-04574	AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)	Mouse	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-01000	BVES Protein, Human, Recombinant (GST)	Human	E. coli
	Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protecti...
TMPJ-00395	SEMA4D Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous t...
TMPY-00585	Annexin A8 Protein, Human, Recombinant (His)	Human	E. coli
	We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA...
TMPY-04036	GM-CSF/CSF2 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-05236	GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated	Human	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-02466	GM-CSF/CSF2 Protein, Human, Recombinant (His)	Human	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPY-03631	GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio...
TMPH-01786	NCBP1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay,...
TMPH-01785	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay,...
TMPH-03281	PRKN Protein, Rat, Recombinant (His & Myc)	Rat	Baculovirus
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-00617	MazF Protein, E. coli, Recombinant (His)	E. coli	Yeast
	Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific endoribonuclease it inhibits protein synthesis by cleaving mRNA and inducing bacterial stasis. It is stable, single-strand specific with mRNA ...
TMPH-01262	PRKN Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, an...
TMPH-01263	PRKN Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-02631	PRKN Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...