synthetic analogue

4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects

Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, acting as a synthetic analogue of flavin mononucleotide (FMN). It suppresses ribB gene expression and inhibits bacterial cell growth.

Taltobulin trifluoroacetate is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

Dehydroemetine is an effective antigenic insecticide, which is a synthetic analogue of Emetine dihydrochloride. It can be used to prevent and treat amoeba infections and diseases. It has the effect of treating leishmania infection with skin damage and resistance to metronidazole amoebiosis.

Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).

Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.

KP-1212 is a synthetic nucleoside analogue that exerts antiviral activity by inducing lethal mutagenesis of the viral genome, thereby increasing mutation rates beyond viral viability thresholds, and has been shown to inhibit HIV growth, making it a valuable research compound for studying antiviral mechanisms, viral replication fidelity, and mutation-driven therapeutic strategies.

2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U.

Naspm is a synthetic analogue of Joro spider toxin and is a antagonist iscalcium permeable AMPA (CP-AMPA) receptors.

Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and acts as an antagonist of calcium-permeable AMPA (CP-AMPA) receptors.

SIBA (5'-Deoxy-5'-isobutylthioadenosine) is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)

Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

Calcipotriol (MC 903) is a synthetic vitamin D3 analogue with high affinity for the vitamin D receptor.

Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.

EC23 (AGN 190205) is a stable synthetic retinoid analogue that induces neuronal differentiation.

PF-06380101 is an auristatin microtubule inhibitor and is a cytotoxic Dolastatin 10 analogue. When compared to other synthetic auristatin analogues that are used in the preparation of ADCs, PF-06380101 displays excellent potencies in tumor cell proliferat

Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).

Arteflene is a synthetic structural analogue derived from artemisinin, exhibiting antimalarial activity.

Cloprostenol is a synthetic prostaglandin and PGF2α analogue used in animals to terminate pregnancy and induce corpus luteum dissolution.

Octaverine is a synthetic analogue of papaverine. In in vivo experiments with rabbits, Octaverine has been shown to reduce adrenaline-induced hypertension and increase ventilation.

Cephalosporin Canalog-1 is an analogue of Cephalosporin C, which exhibits relatively weak resistance to both Gram-positive and Gram-negative bacteria. Cephalosporin C is stable against penicillinase but can be decomposed by cephalosporinase. Through hydrolysis, its side chain can be removed to yield 7-amino-cefenoic acid (7-ACA), an essential raw material for producing semi-synthetic cephalosporins.

Apoptone is a synthetic analogue of 3β-androstanediol which is an orally bioavailable anticancer agent. Apoptone is active in rodent models of prostate and breast cancer [1].

Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic analogue of PGF2α with oxytocic properties, commonly used to restore uterine tone.

Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity,which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, deple