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Search Result

Search Results for " sulfonylurea "

Targets

Others

38

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8345 Carbutamide Others
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.
T21246 Metsulfuron-methyl Others
Metsulfuron-methyl is a systemic selective wheat field high-efficiency sulfonylurea herbicide, which mainly controls most broadleaf weeds and grass weeds in wheat fields.
T19859 Nicosulfuron Milagro,Accent,Motivell Others
Nicosulfuron (Milagro) is a pesticide that works by inhibiting the acetolactate synthase enzyme. Nicosulfuron has not been found to induce mutagenic or carcinogenic effects. Nicosulfuron is a herbicide to protect corn cr...
T9222 Emlenoflast MCC7840 NOD-like Receptor (NLR) , NOD
Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.
T20623 Thifensulfuron-methyl Harmony GT,Refine,Pinnacle Others
Thifensulfuron-methyl (Pinnacle) is a sulfonylurea (SU) herbicide, has an important role in the removal of broadleaf weeds.
T20804 Bensulfuron-methyl F-5384,DPX 84,F5384,F 5384 Others
Bensulfuron-methyl (F 5384) is a broad-spectrum herbicide for broadleaf weeds in paddy fields.
T1603 Glipizide CP 28720,K 4024 Potassium Channel , PPAR , ABC
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
T0816 Acetohexamide Acetohexamid,Dymelor,Gamadiabet Potassium Channel , NADPH
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) wi...
T0127 Glimepiride Glimperide,HOE-490 Potassium Channel
Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.
T0490 Chlorpropamide Diabinese ATPase , ABC
Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.
T16420 P-1075 Potassium Channel
P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of sulfonylurea receptor 2-associated ATP-sensitive potassium c...
T1527 Gliclazide S1702,SE1702 Potassium Channel
Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the pancreas to release insulin.
T1410 Torsemide AC-4464,JDL-464,Torasemide Na-K-Cl cotransporter
Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...
T0371 Gliquidone AR-DF 26,Glurenorm Potassium Channel
Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding affinity to SUR1 and increased potency compared...
T1634 Glibenclamide Glyburide Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T20722 Flucetosulfuron LGC-42153,LGC 42153,LGC42153
Flucetosulfuron is a sulfonylurea herbicide
T38456 Tribenuron
Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.
T0371L Gliquidone sodium
Gliquidone sodium is a hypoglycemic sulfonylurea which may protect the liver from injury from diabetes.
T31966 Glycyclamide TOLCYCLAMIDE,Tolhexamide,Cyclamide,Glycyclamid,Gliciclamide
Glycolamide is a sulfonylurea compound containing cyclohexyl groups.
T27883 LY 181984 LY181984,LY-181984,MPCU
LY 181984 is an sulfonylurea with antitumor properties.
T13712 Glyparamide Others
Glyparamide is a chlorophenyl-containing sulfonylurea with hypoglycemic activity.
TP2383 Glipentide Staticum,UR661,UR-661,UR 661,Glisentide
Glieptide, a second-generation sulfonylurea, promotes the accumulation of fructose 2, 6-diphosphate in liver cells.
T35641 Trans-hydroxy Glimepiride
trans-hydroxy Glimepiride is an active metabolite of the sulfonylurea glimepiride .1It is formed from glimepiride primarily in the liver by the cytochrome P450 (CYP) isoform CYP2C9. 1.Langtry, H.D., and Balfour, J.A.Glim...
T38615 Rimsulfuron DPX-E9636,Rimsulfuron
Rimsulfuron (DPX-E9636) is a sulfonylurea herbicide specifically designed for postemergence application in maize crops. This compound effectively targets and manages grasses as well as certain types of broadleaf weeds.
T61461 Anticancer agent 37
Anticancer agent 37 (compound 18) is a sulfonylurea derivative known for its potent anticancer activity. It efficiently inhibits the growth of HePG2 cells, displaying an IC 50 value of 17.2 μg/mL [1].
T14040 4-Hydroxytolbutamide Hydroxytolbutamide Potassium Channel
4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic[1][2].
T35640 Trans-carboxy Glimepiride
trans-carboxy Glimepiride is a metabolite of the sulfonylurea glimepiride .1It is formed from glimepiride in a two-step process mediated by the cytochrome P450 (CYP) isoform CYP2C9 and cytosolic enzymes. 1.Noh, K., Kim, ...
T9222L Emlenoflast sodium MCC7840 sodium NOD
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in the study of inflammatory diseases.
T61602 Anticancer agent 35
Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 35 inhibits A549, A431, PACA2 cell growth with IC 50 s of 18.1 μg/mL, 4.0 μg/mL, 18.9 μg/mL, respectively [1].
T36740 Guanosine 5’-diphosphate (sodium salt hydrate)
Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR...
T71284 Glimepiride urethane
Glimepiride urethane is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Gli...
T80642 Foramsulfuron
Foramsulfuron, a postemergence sulfonylurea herbicide, selectively controls grass and certain broadleaved weeds in maize (Zea mays L.). It targets acetolactate synthase (ALS), an essential enzyme in the biosynthesis of b...
T35635 Rac-trans-4-hydroxy Glyburide
rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide .1,2It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9.1rac-trans-4-hydroxy Glybu...
T62278 Anticancer agent 36
Anticancer agent 36 (compound 11) is a potent anti-microbial and anti-cancer agent, a sulfonylurea derivative. anticancer agent 36 inhibits the microbial growth of Bacillus mycoides, Escherichia coli and Candida albicans...
T62754 Anticancer agent 34
Anticancer agent 34 (compound 9) is a sulfonylurea derivative and a potent anti-microbial and anti-cancer agent. anticancer agent 34 showed inhibition of microbial growth of Mycobacterium, Escherichia coli and Candida al...
T71402 Nicorandil-d4
Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir...
T71981 Gliclazide-d4
Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. ...
T79446 INF200 NOD-like Receptor (NLR)
INF200 (compound 5), a sulfonylurea-based inhibitor of NLRP3 and associated pyroptosis, exhibits cardiometabolic benefits in a rat model of high-fat diet (HFD)-induced metaflammation and demonstrates anti-inflammatory ef...

Compounds

Carbutamide
T8345
Synonym:
Target: Others
Metsulfuron-methyl
T21246
Synonym:
Target: Others
Nicosulfuron
T19859
Synonym: Milagro,Accent,Motivell
Target: Others
Emlenoflast
T9222
Synonym: MCC7840
Target: NOD-like Receptor (NLR), NOD
Thifensulfuron-methyl
T20623
Synonym: Harmony GT,Refine,Pinnacle
Target: Others
Bensulfuron-methyl
T20804
Synonym: F-5384,DPX 84,F5384,F 5384
Target: Others
Glipizide
T1603
Synonym: CP 28720,K 4024
Target: Potassium Channel, PPAR, ABC
Acetohexamide
T0816
Synonym: Acetohexamid,Dymelor,Gamadiabet
Target: Potassium Channel, NADPH
Glimepiride
T0127
Synonym: Glimperide,HOE-490
Target: Potassium Channel
Chlorpropamide
T0490
Synonym: Diabinese
Target: ATPase, ABC
P-1075
T16420
Synonym:
Target: Potassium Channel
Gliclazide
T1527
Synonym: S1702,SE1702
Target: Potassium Channel
Torsemide
T1410
Synonym: AC-4464,JDL-464,Torasemide
Target: Na-K-Cl cotransporter
Gliquidone
T0371
Synonym: AR-DF 26,Glurenorm
Target: Potassium Channel
Glibenclamide
T1634
Synonym: Glyburide
Target: Potassium Channel, Mitochondrial Metabolism, CFTR, P-gp, Autophagy
Flucetosulfuron
T20722
Synonym: LGC-42153,LGC 42153,LGC42153
Target:
Tribenuron
T38456
Synonym:
Target:
Gliquidone sodium
T0371L
Synonym:
Target:
Glycyclamide
T31966
Synonym: TOLCYCLAMIDE,Tolhexamide,Cyclamide,Glycyclamid,Gliciclamide
Target:
LY 181984
T27883
Synonym: LY181984,LY-181984,MPCU
Target:
Glyparamide
T13712
Synonym:
Target: Others
Glipentide
TP2383
Synonym: Staticum,UR661,UR-661,UR 661,Glisentide
Target:
trans-hydroxy Glimepiride
T35641
Synonym:
Target:
Rimsulfuron
T38615
Synonym: DPX-E9636,Rimsulfuron
Target:
Anticancer agent 37
T61461
Synonym:
Target:
4-Hydroxytolbutamide
T14040
Synonym: Hydroxytolbutamide
Target: Potassium Channel
trans-carboxy Glimepiride
T35640
Synonym:
Target:
Emlenoflast sodium
T9222L
Synonym: MCC7840 sodium
Target: NOD
Anticancer agent 35
T61602
Synonym:
Target:
Guanosine 5’-diphosphate (sodium salt hydrate)
T36740
Synonym:
Target:
Glimepiride urethane
T71284
Synonym:
Target:
Foramsulfuron
T80642
Synonym:
Target:
rac-trans-4-hydroxy Glyburide
T35635
Synonym:
Target:
Anticancer agent 36
T62278
Synonym:
Target:
Anticancer agent 34
T62754
Synonym:
Target:
Nicorandil-d4
T71402
Synonym:
Target:
Gliclazide-d4
T71981
Synonym:
Target:
INF200
T79446
Synonym:
Target: NOD-like Receptor (NLR)

Recombinant Proteins

Species：
Human (2)
Expression System：
E. coli (2)
Tag：
His (2)
Cat No. Product Name Species Expression System
TMPY-05654 ENSA Protein, Human, Recombinant (His), Biotinylated Human E. coli
Endosulfine alpha, also known as ENSA, belongs to the endosulfine family. It is a highly conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine alpha is widely expressed with high levels in skeletal muscle ...
TMPY-03411 ENSA Protein, Human, Recombinant (His) Human E. coli
Endosulfine alpha, also known as ENSA, belongs to the endosulfine family. It is a highly conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine alpha is widely expressed with high levels in skeletal muscle ...
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