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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

Search Result

Search Results for "stability"

Libraries

High Solubility Micro Fragment Library Cyclic Peptide Library Methylation Compound Library Fluorochemical Library Cytoskeletal Signaling Pathway Compound Library
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Compounds

Cat No. Product Name
T7879 TASP0415914 PI3K , Akt
TASP0415914 是一种具有口服活性的 PI3Kγ抑制剂，其 IC50=29 nM。它是一种 Akt 抑制剂，其 IC50=294 nM。它可用于研究炎症性疾病。
T4893 Spermidine N-(3-Aminopropyl)-1,4-diaminobutane,N-(4-Aminobutyl)-1,3-diaminopropane,亚精胺 Endogenous Metabolite
Spermidine 能够维持细胞膜稳定性，提高抗氧化酶活性，改善光系统 II 以及相关基因表达。它结合并激活 NMDA，并已显示以浓度依赖性方式增强 NMDA 诱导的电流。
T5080 Spermidine trihydrochloride 三盐酸亚精胺,亚精胺盐酸盐,4-Azaoctamethylenediamine trihydrochloride,Spermidine hydrochloride Autophagy , NMDAR
Spermidine hydrochloride 能够维持细胞膜稳定性，提高抗氧化酶特性，改善光系统 II (PSII) 以及相关基因表达，也能够显著抑制 H2O2和 O2.-含量。
T4925 Thiamine monophosphate chloride (dihydrate) 胺氯化亚磷酸酯,Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride Endogenous Metabolite , Others
Thiamine monophosphate chloride dihydrat 是内源性代谢产物的一种。
T6928 Pantoprazole SKF96022,BY1023,泮托拉唑 Autophagy , Proton pump , Apoptosis
Pantoprazole 是一种质子泵抑制剂，用于短期治疗由胃食管反流病引起的食管糜烂和溃疡。它联合阿霉素可显著增加肿瘤生长延迟。它是一种取代的苯并咪唑，是H+/K+-ATPase 抑制剂，可改善 pH 值稳定性，具有抗分泌和抗溃疡的作用。
T11717 JHU395 Apoptosis
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It...
T4S2014 5,15-Diacetyl-3-benzoyllathyrol Euphorbia factor L3,，大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇；千金二萜醇二乙酰苯甲酰酯 Others
5,15-Diacetyl-3-benzoyllathyrol 是一种具有抗癌作用的萜类化合物。
T10002 (E)-Crotylbarbital Kalypnon Others
(E)-Crotylbarbital 是Crotylbarbital 的异构体，是一种巴比妥酸衍生物，具有镇静、催眠和抗惊厥的作用。(E)-Crotylbarbital 可用于促进精神安定和睡眠的研究。
T4A2456 Gamabufotalin 日本蟾蜍毒苷元,Gamabufagin COX
Gamabufotalin 是一种蟾蜍甾烯，存在于蟾酥中。它稳定性高，毒性低，被广泛用于癌症的研究。
T6705 TIC10 Isomer ONC201 isomer,TIC10 Analogue Others
TIC10 isomer 是一种 TIC10 的异构体。它不能诱导 TRIAL 表达的生物学活性。
T19609 (2-Hydroxypropyl)-β-cyclodextrin 羟丙基-BETA-环糊精,羟丙基-β-环糊精,HP-β-CD,Hydroxypropyl-β-cyclodextrin,Hydroxypropyl betadex Others
(2-Hydroxypropyl)-β-cyclodextrin 是一种药物递送载体，可提高稳定性和利用度。
T9058 Bisphenoxyethanolfluorene Others
Bisphenoxyethanolfluorene 是一种高稳定性的新型有机化工原料，主要用于合成耐热、透明性和高折射率的高分子单体。
T15409 GNF179 Parasite
GNF179 是8,8-二甲基 IP 类似物。 它表现出对多药耐药菌株 W2 的效力，具有良好的体外代谢稳定性和体内口服生物相容性。
T1614 Hydrocortisone 氢化可的松,Cortisol Glucocorticoid Receptor , Endogenous Metabolite
Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
T19853 Dimethoxycurcumin Veratrylcurcuminoid,二甲氧基姜黄素 Others
Dimethoxycurcumin 是 curcumin 衍生物，拥有抗氧化及抗炎作用。
T21673 N-Isopropylnoratropine Others
N-Isopropylnoratropine 是一种去甲托品衍生物，是生产异丙托溴铵(ipratropium) 的中间体，异丙托溴铵是一种通过抗胆碱能途径产生的阿托品样支气管扩张药。 它用于检查异丙托溴铵的稳定性。
T8160 EGCG Octaacetate 乙酰化EGCG,乙酰化表没食子儿茶素没食子酸酯 Antibacterial , Others
EGCG Octaacetate 是表没食子儿茶素没食子酸酯的前药，对革兰氏阳性菌和革兰氏阴性菌有潜在抗菌可能。它可下调 PI3K/Akt/NFκB 磷酸化和 p65 乙酰化来降低促炎介质水平，减少小鼠结肠炎引起的结肠癌。
T9698 UC2288 p53 , Mdm2
UC2288 是新型的、细胞通透性、口服有效的p21衰减试剂，基于索拉非尼的结构合成。在不依赖 于p53的情况下，它可以下调 p21 mRNA 的表达，降低 p21 蛋白水平，对 p21 蛋白的稳定性影响很小。它对VEGFR2 和 Raf ...
TN1608 (-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-EGCG-3''-O-ME Antioxidant , Antibacterial
(-)-Epigallocatechin-3-(3''-O-methyl) gallate 是从茶叶中分离出的一种天然产物，具有很强的抗氧化、细胞毒性和抗菌活性，可增强蚀刻漂洗粘合剂与牙本质的粘合稳定性。
TN1275 P-Hydroxyphenethyl anisate 4-Hydroxyphenethylanisate Others
p-Hydroxyphenethyl anisate 是一种来自 Notopterygium forbe-siiBoiss 的天然产品，是一种新型聚合物缓释材料，与 AAPBA 嵌段共聚后， 制备的纳米颗粒具有良好的 Ph 敏感性、葡萄糖敏...
TASP0415914
T7879
synonym:
Target:
Spermidine
T4893
synonym: N-(3-Aminopropyl)-1,4-diaminobutane,N-(4-Aminobutyl)-1,3-diaminopropane,亚精胺
Target:
Spermidine trihydrochloride
T5080
synonym: 三盐酸亚精胺,亚精胺盐酸盐,4-Azaoctamethylenediamine trihydrochloride,Spermidine hydrochloride
Target:
Thiamine monophosphate chloride (dihydrate)
T4925
synonym: 胺氯化亚磷酸酯,Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride
Target:
Pantoprazole
T6928
synonym: SKF96022,BY1023,泮托拉唑
Target:
JHU395
T11717
synonym:
Target:
5,15-Diacetyl-3-benzoyllathyrol
T4S2014
synonym: Euphorbia factor L3,，大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇；千金二萜醇二乙酰苯甲酰酯
Target:
(E)-Crotylbarbital
T10002
synonym: Kalypnon
Target:
Gamabufotalin
T4A2456
synonym: 日本蟾蜍毒苷元,Gamabufagin
Target:
TIC10 Isomer
T6705
synonym: ONC201 isomer,TIC10 Analogue
Target:
(2-Hydroxypropyl)-β-cyclodextrin
T19609
synonym: 羟丙基-BETA-环糊精,羟丙基-β-环糊精,HP-β-CD,Hydroxypropyl-β-cyclodextrin,Hydroxypropyl betadex
Target:
Bisphenoxyethanolfluorene
T9058
synonym:
Target:
GNF179
T15409
synonym:
Target:
Hydrocortisone
T1614
synonym: 氢化可的松,Cortisol
Target:
Dimethoxycurcumin
T19853
synonym: Veratrylcurcuminoid,二甲氧基姜黄素
Target:
N-Isopropylnoratropine
T21673
synonym:
Target:
EGCG Octaacetate
T8160
synonym: 乙酰化EGCG,乙酰化表没食子儿茶素没食子酸酯
Target:
UC2288
T9698
synonym:
Target:
(-)-Epigallocatechin-3-(3''-O-methyl) gallate
TN1608
synonym: (-)-EGCG-3''-O-ME
Target:
p-Hydroxyphenethyl anisate
TN1275
synonym: 4-Hydroxyphenethylanisate
Target:
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