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stability

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    384
    TargetMol | Inhibitors_Agonists
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    6
    TargetMol | Compound_Libraries
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    25
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    TargetMol | Isotope_Products
Pantoprazole Sodium Hydrate
SKF96022 sodium hydrate, SKF96022 (sodium hydrate), BY1023 (sodium hydrate)
T0161164579-32-2
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
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TargetMol | Inhibitor Sale
Spermidine
N-(4-Aminobutyl)-1,3-diaminopropane, N-(3-Aminopropyl)-1,4-diaminobutane
T4893124-20-9
Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). Spermidine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner.
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TargetMol | Citations Cited
TIC10
ONC-201
T70011616632-77-9
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1 2.
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TargetMol | Inhibitor Hot
HIF-2α agonist 2
T678312750141-15-0In house
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reha-Luc cells. HIF-2α agonist 2 can be used in the study of oxygen metabolism and is closely related to the occurrence of cancer.
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8-10weeks
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Vutiglabridin
HSG4112
T612681800188-47-9In house
Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stability. vutiglabridin ameliorates mptp-induced neurodegeneration in Parkinson's disease mice by targeting mitochondrial paraoxonase-2. Vutiglabridin is a clinical phase 2 drug for the treatment of obesity and has therapeutic effects on p-mitochondrial PON2 in a PD model. vutiglabridin penetrates the brain, binds PON2, and restores 1-methyl-4-phenylpyridine (MPP*)-induced neuroblastoma in SH-SY5Y Vutiglabridin significantly attenuated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dyskinesia and dopaminergic neuronal damage in mice modeled with PD in mouse experiments.
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6-8weeks
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JHU395
T117172079938-92-2In house
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo, resulting in significant antitumor activity in MPNST. Additionally, JHU395 exhibits plasma stability.
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8-10weeks
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(E)-Crotylbarbital
Kalypnon
T1000228360-89-6In house
(E)-Crotylbarbital (Kalypnon), an isomer of Crotylbarbital, is a barbiturate derivative that has sedative, hypnotic, and anticonvulsant effects. (E)-Crotylbarbital can be used in studies to promote mental stability and sleep.
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6-8weeks
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6-Chloromelatonin
T2253063762-74-3In house
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for presynaptic melatonin receptor sites in the rabbit retina, inhibiting the calcium-dependent release of [3H]dopamine with higher metabolic stability than melatonin. Chloromelatonin competitively binds to [3H]melatonin at MT2 receptors (pKi=9.77) and may be used to study insomnia and sleep disorders associated with depression.
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6-8weeks
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10-(Phosphonooxy)decyl methacrylate
T8421685590-00-7
10-(Phosphonooxy)decyl methacrylate (10-methacryloyloxydecyl dihydrogen phosphate) is an adhesive that can modify the surface of dentin and improve the stability of dentin bonding.
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Cefuroxime sodium
Cefuroxime sodium salt, Biociclin, Anaptivan
T122456238-63-2
Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime sodium salt) inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.
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Citric acid monohydrate
T56695949-29-1
Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative.
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Spermidine trihydrochloride
Spermidine hydrochloride, 4-Azaoctamethylenediamine trihydrochloride
T5080334-50-9
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).
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Propyl dodecanoate
Propyl laurate
T841513681-78-5
Propyl dodecanoate (Propyl laurate) is often added to skin care products to improve the touch of the product and increase the stability of the product.
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Sodium dodecyl sulfate
Sodium lauryl sulfate, Sodium dodecylsulfate, SDS, NSC-402488, NSC402488, NSC 402488, Natrium laurylsulfuricum, Laurylsulfuric acid sodium salt, Anticerumen
T20075151-21-3
Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations.
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2,2'-Bipyridine
Fr14395366-18-7
2,2'-Bipyridine is a unique bioactive natural product molecular scaffold commonly used in the core structure of many chelating ligands. 2,2'-Bipyridine acts as a bridge in the arrangement of the catalytic center. 2,2'-Bipyridine has good redox stability and glycemic activity.
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7-10 days
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trans-Urocanic Acid
trans-UCA, (E)-Urocanic acid
T375473465-72-3
trans-Urocanic Acid ((E)-Urocanic acid), a compound predominantly distributed in the hippocampus and prefrontal cortex, is an isomer of cis-UCA, an epidermal UV-protectant, which enhances the stability of tenofovir eplerenomide in long-acting HIV applications. trans-Urocanic acid potently modulates immune trans-urocanic acid effectively modulates immune function, inhibits human natural killer cell activity in vitro, and can be used in Alzheimer's disease research.
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6-8 weeks
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Boc-His-OH
N-Boc-L-Histidine, Boc-L-Histidine
T6752017791-52-5
Boc-His-OH is a protected amino acid derivative widely used in peptide synthesis and biochemical studies.N-Boc-L-Histidine is used as an intermediate in peptide synthesis for the construction of polypeptide chains with good chemical stability and solubility.
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7-10 days
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Thiamine monophosphate chloride (dihydrate)
Thiamine monophosphate chloride dihydrat, Aneurine monophosphate chloride
T4925273724-21-3
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability
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Pantoprazole sodium
Pantecta, SKF96022 sodium, SKF96022 (sodium), BY1023 (sodium), BY-1023 sodium, Pantoloc
T6929138786-67-1
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+ K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.
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Chlorobutanol
YM-57158, Chlortran, Chloretone, Chloreton, Chlorbutol
T090157-15-8
Chlorobutanol (Chlortran) is a chemical preservative, sedative hypnotic and weak local anaesthetic. It has Antibacterial and Antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lends long-term stability to multi-ingredient formulations.
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Rebaudioside D
T2S184063279-13-0
Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected from the cecum.
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HP-β-CD
Hydroxypropyl-β-cyclodextrin, Hydroxypropyl betadex
T19609128446-35-5
HP-β-CD (HP-β-CD) is a widely used drug delivery vehicle to improve stability and bioavailability.
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Pantoprazole
SKF96022, BY1023
T6928102625-70-7
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
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L-Alanyl-L-glutamine
Ala-Gln
T559339537-23-0
L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).
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