saussurea

Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.

Saussureamine C is an inhibitor of H274Y and N294S mutants.

Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.

Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.

(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plants of the Asteraceae, including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin.

4-Ethyloctanoic acid, a natural product isolated from Saussurea lappa Clarke, is used as a food additive and industrial perfume, among other applications.

2-Ethylphenol (Standard) is an analytical standard substance, typically employed as a reference sample for research and analysis involving 2-Ethylphenol.

Luteolin-7-rutinoside is a natural product that alleviates LPS-induced acute liver injury by inhibiting the PI3K/AKT/AMPK/NF-κB signaling pathways and suppressing TNF-α, IL-6, and IL-1β.

Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.

Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

Thunberginol C exhibits antimicrobial activity against oral bacteria. It shows antiallergic activity in the in vitro bioassay using the Schults-Dale reaction in sensitized guinea pig bronchial muscle.

Arctigenin (Standard) is a reference standard for research and analysis in studies involving Arctigenin. (-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plants of the Asteraceae, including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin.

29-Nor-20-oxolupeol(3 beta-Hydroxy-30-norlupan-20-one) has growth inhibitory effects on HL-60 cells.

8-Epicrepiside E is a natural product of Saussurea, Asteraceae. The catalog number is TN3275 and the CAS number is 93395-30-3. 8-Epicrepiside E can be used as a reference standard.

Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. They reduce Allium cepa cell

Matairesinoside is a lignan extracted from the stem bark of Styrax japonica S. et Z, which is known to exhibit antibacterial and antioxidant properties while also functioning as a virus–cell fusion inhibitor. Matairesinoside acts as a potent inhibitor of TMEM16A, a novel target implicated in lung cancer progression, confirmed through molecular simulation and site-directed mutagenesis. Matairesinoside significantly reduces lung cancer cell growth, migration, and invasion while inducing apoptosis, with gene knockdown and overexpression demonstrating TMEM16A as the direct target and Western blot analysis elucidating the associated signaling pathways involved in tumor suppression.

Sulfocostunolide A is a natural product of Saussurea, Asteraceae. The catalog number is TN5077 and the CAS number is 1016983-51-9. Sulfocostunolide A can be used as a reference standard.

Sulfocostunolide B is a natural product of Saussurea, Asteraceae. The catalog number is TN5078 and the CAS number is 1059671-65-6. Sulfocostunolide B can be used as a reference standard.

Isozaluzanin C (Dehydrozaluzanin C-derivative) is an anti-inflammatory compound isolated from Saussurea lappa with immunomodulatory properties. It mitigates tissue damage in the lungs, kidneys, and liver and reduces excessive inflammation in mice caused by LPS or CRKP infection. Isozaluzanin C is valuable for researching bacterial infections and sepsis [1] [2].