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RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53 Mdm2 interaction.

Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.

Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist with an IC50 of 0.9 nM.

Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.

Neobritannilactone B is a useful organic compound for research related to life sciences and the catalog number is T123996.

Aceritannin is a useful organic compound for research related to life sciences. The catalog number is T124250 and the CAS number is 76746-56-0.

1-O-Acetyl-6beta-O-Isobutyrylbritannilactone is a valuable organic compound for life sciences research, with catalog number [T126430].

N'-Phenacylpiperazinebritanin is a useful organic compound for research related to life sciences and the catalog number is T131471.

Neritaloside is a natural product from Nerium oleander.

Paritaprevir (ABT450) is an inhibitor of non-structural protein 3 4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.

Eritadenine (Lentinacin) is a mushroom-derived compound that acts on the adenosine P-site in adipocyte plasma membranes, lowering cholesterol levels and altering phospholipid composition in rat models of hyperhomocysteinemia, used in anxiety disorder studies.

Oritavancin diphosphate (LY333328 diphosphate) is a novel semisynthetic glycopeptide antibiotic developed for treating serious Gram-positive bacterial infections.

Deferitazole magnesium is a potential chelator for iron overload treatment.

Paritaprevir free base(ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3 NS4A), with potential activity against HCV genotype 1. Upon administration, paritaprevir reversibly binds to the active center and binding site of the HCV NS3 NS4A protease and prevents NS3 NS4A protease-mediated polyprotein maturation. This disrupts both the processing of viral proteins and the formation of the viral replication complex, which inhibits viral replication in HCV genotype 1-infected host cells. NS3, a serine protease, is essential for the proteolytic cleavage of multiple sites within the HCV polyprotein and plays a key role during HCV ribonucleic acid (RNA) replication. NS4A is an activating factor for NS3. HCV is a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family, and infection is associated with the development of hepatocellular carcinoma (HCC).

Oritavancin is a novel semisynthetic glycopeptide antibiotics. On August 6, 2014, the FDA approved oritavancin for treatment of skin infections. Oritavancin possesses potent and rapid bactericidal activity in vitro against a broad spectrum of both resistant and susceptible Gram-positive bacteria, including Staphylococcus aureus, MRSA, enterococci, and streptococci.

Peritassine A, an alkaloid derived from Tripterygium wilfordii Hook. f., exhibits anti-HIV properties.

Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.

Ritanserin tartrateis is a selective and potent serotonin-2 antagonist.

Paritaprevir dihydrate (ABT-450), a highly effective and orally administered antiviral, acts as a non-structural protein 3 4A (NS3 4A) protease inhibitor, displaying EC50 values of 1 and 0.21 nM against HCV genotypes 1a and 1b, respectively. Additionally, it functions as a SARS-CoV 3CL pro inhibitor with an IC50 of 1.31 μM. Primarily metabolized by cytochrome P450 (CYP) 3A, its plasma concentration and half-life are significantly increased when administered with Ritonavir, a CYP450 inhibitor [1] [2] [3] [4].

6-O-Isobutyrylbritannilactone, a sesquiterpene natural melanogenesis inhibitor, can be extracted from Inula britannica flowers. It effectively suppresses IBMX-induced melanin production in B16F10 cells and exerts antimelanogenic effects in zebrafish embryo models by modulating ERK, PI3K AKT, and CREB pathways [1].

Zuberitamab (HS006) is a monoclonal antibody targeting CD20, utilized in cancer research, notably in diffuse large B-cell lymphoma [1].

Epcoritamab (GEN3013) is a novel subcutaneous CD3xCD20 bispecific T-cell binding antibody that activates T-cells and directs them to kill malignant CD20(+) B-cells for the study of relapsed or refractory large B-cell lymphoma.

Inubritannolide A exhibits moderate to robust neuroprotective effects across various neuronal cell types against inducers such as H2O2, 6-hydroxydopamine (6-OHDA), and lipopolysaccharide (LPS).

Epcoritamab-CD20 Specific Antibody is an inhibitory antibody that can be used in life science related research.