rhythms

Drobuline hydrochloride, an anti-arrhythmic agent with cardiac depressant activity, is used to manage abnormal heart rhythms.

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

(E Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.

1A-116 is a specific inhibitor of Rac1 .

Stirocainide is an antiarrhythmic compound utilized in the treatment of irregular heart rhythms.

Gallopamil HCl, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.

Gallopamil, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.

GR 196429, a melatonin receptor agonist, exhibits selectivity for the MT1 subtype. This compound not only promotes sleep and alters circadian rhythms but also stimulates melatonin release in mice.

KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP PKA CREB pathway.

FT709 is a selective and potent inhibitor of USP9X (IC50: 82 nM), a protein associated with centrosome function, EGF receptor degradation, chromosome alignment during mitosis, chemosensitization, and circadian rhythms.

PF-05236216 hydrochloride is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta epsilon (CK1δ ε) that modulates circadian rhythms in mice.

Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormally fast heart rhythms).

VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening.

KL201, a circadian clock modulator, is an isoform-selective cryptochrome 1 (CRY1) stabilizer that lengthens the period of circadian rhythms in cells and tissues [1].

Flecainide-d4 Acetate is a deuterated compound of Flecainide Acetate. Flecainide Acetate has a CAS number of 54143-56-5. Flecainide (acetate) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).

Quinidine-d3 is a deuterated compound of Quinidine. Quinidine has a CAS number of 56-54-2. Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.