26
1
5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9833 | Opiranserin hydrochloride | P2X Receptor , GlyT , 5-HT Receptor | |
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50... | |||
T1242 | Alvimopan | Opioid Receptor | |
Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid... | |||
T1780 | Parecoxib | SC 69124,Vorth-P,Valus-P | COX |
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor. | |||
T21412 | Ketorolac | Toradol,Sprix,Acuvail,Macril,Acular | COX |
Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins. | |||
T3126 | Bethanechol chloride | (±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride | AChR |
Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab... | |||
T16399 | Opiranserin | P2X Receptor , GlyT , 5-HT Receptor | |
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) an... | |||
T1406 | Amantadine hydrochloride | 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride | Dopamine Receptor , Influenza Virus |
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease. | |||
T68057 | Doxpicomine | Others | |
Doxpicomine has analgesic activity and can be used to treat postoperative pain. | |||
T8157 | Centhaquin | PMZ-2010,Centhaquine | Others |
Centhaquin (Centhaquine)e is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock | |||
T6236 | Ozagrel | OKY-046,Domenan | Thrombin , Prostaglandin Receptor |
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch... | |||
T6625 | Ozagrel hydrochloride | Ozagrel HCl,OKY-046 HCl | Thrombin , Prostaglandin Receptor |
Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. | |||
T31759 | Felbinac Trometamol | L141,Felbinac,L-141,L 141 | |
Felbinac Trometamol is an intravenous preparation used to treat severe postoperative pain. | |||
T27079 | CR-665 Acetate | FE200665,CR-665,JNJ-38488502,CR665,FE-200665,JNJ38488502 | |
CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain. | |||
T28703 | SC-75416 | SC75416 | |
SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation. | |||
T80501 | Myr-TAT-CBD3 | Calcium Channel | |
Myr-TAT-CBD3, a CRMP2-CaV2.2 interaction inhibitor, has been shown to significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity in a rat model of postoperative pain, making... | |||
T71551 | KAI-1678 | ||
KAI-1678 is an inhibitor of epsilon protein kinase C (εPKC). KAI-1678 is effective in the treatment of postoperative pain following total hip or total knee replacement. | |||
T71601 | CU-2010 | ||
CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a... | |||
T68563 | Piroxicam olamine | ||
Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmeno... | |||
T73233 | Ciramadol | WY 15705 | |
Ciramadol (WY 15705) is a potent and orally active analgesic agent with both narcotic agonist and antagonist properties . Ciramadol (WY 15705) can be used for postoperative pain treatment research. | |||
T60435 | Propacetamol | ||
Propacetamol is an analgesic agent and a prodrug that is metabolized to paracetamol. It can be used for postoperative pain, acute trauma, and gastrointestinal disorders[1]. | |||
T1780L | Parecoxib sodium | SC 69124A,SC-69124A,SC69124A,Dynastat | |
Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in t... | |||
T68211 | Piroxicam betadex | ||
Piroxicam betadex is a nonsteroidal anti-inflammatory drug. The mechanism of action of piroxicam is as a cyclooxygenase Inhibitor. It is well established in treating rheumatoid arthritis and osteoarthritis and used for ... | |||
T22238 | Alvimopan dihydrate (LY246736 dihydrate) | ||
Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan dihydrate is highly selective for μ-opioid receptor ( Ki =0... | |||
T60496 | Ketorolac hemicalcium | ||
Ketorolac (RS37619) hemicalcium is a nonselective COX inhibitor with IC50s of 20 nM and 120 nM for COX-1 and COX-2, respectively. Ketorolac hemicalcium is a non-steroidal anti-inflammatory drug (NSAID) that is used as 0.... | |||
T71212 | Lornoxicam-d4 | ||
Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and an... | |||
T35593 | Semapimod tetrahydrochloride | ||
Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6. Semapimod tetrahydrochloride inhibits TLR4 signaling (IC50≈0.3 μM). Semapimod tetrahydroch... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00669 | SFRP2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in t... | |||
TMPK-01142 | SFRP2 Protein, Human, Recombinant (His) | Human | HEK293 |
As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in t... | |||
TMPY-00010 | LDHA Protein, Mouse, Recombinant (His) | Mouse | E. coli |
LDHA (Lactate Dehydrogenase A) is a Protein Coding gene. The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA, a key enzyme r... | |||
TMPY-04241 | LDHA Protein, Rat, Recombinant (His) | Rat | E. coli |
LDHA (Lactate Dehydrogenase A) is a Protein Coding gene. The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA, a key enzyme r... | |||
TMPY-01742 | Acetylcholinesterase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role... |