omeprazole

Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).

Omeprazole sulfone is a metabolite of Omeprazole that inhibits the proton pump.

Omeprazole magnesium, an orally active proton pump inhibitor (PPI), suppresses gastric acid and is utilized for managing symptoms related to acid reflux and frequent heartburn.

Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.

Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).

Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases

Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases

Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases

4-Desmethoxy Omeprazole, the active metabolite of Omeprazole, acts as a proton pump inhibitor (PPI) and demonstrates competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM.

Omeprazole-d3 is a stable deuterated derivative of omeprazole. Omeprazole is a selective proton pump inhibitor (PPI) used in research related to gastrointestinal diseases. Omeprazole inhibits the proliferation and adhesion of Helicobacter pylori and disrupts the stability of the bacterial cell membrane. Omeprazole inhibits the growth of both Gram-positive and Gram-negative bacteria.

Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.

5-hydroxy Omeprazole is one of the major metabolites of the proton pump inhibitor omeprazole in the body; it is formed by hydroxylation catalyzed by the CYP2C19 and CYP3A4 enzymes in the liver. 5-hydroxy Omeprazole can be used in pharmacokinetic studies.

Esomeprazole strontium is a gastric proton pump inhibitor.

GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 µM, respectively.GNE-900 enhances DNA damage and induces apoptosis. GNE-900 has antitumor activity.

(R)-Omeprazole is a useful organic compound for research related to life sciences. The catalog number is T66287 and the CAS number is 119141-89-8.

Omeprazole N-oxide, a metabolite of the gastric proton pump inhibitor omeprazole, serves as a potential impurity in commercial omeprazole preparations.

4-Hydroxy Omeprazole sulfide, a metabolite of the proton pump inhibitor omeprazole, has been detected in wastewater effluent.

Omeprazole impurity 13 is an impurity of Omeprazole.

(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).

Omeprazole (Standard) is the standard substance of Omeprazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).

Omeprazole-[13C,D3] (Standard) is a reference standard of Omeprazole-[13C,D3] intended for quantitative analysis, quality control, and related biochemical research applications.

Omeprazole-D3 (Benzimidazole-4,6,7-D3) (Standard) is a reference standard of Omeprazole-D3 (Benzimidazole-4,6,7-D3) intended for quantitative analysis, quality control, and related biochemical research applications.

Omeprazole-[D3] Sulfone (Benzimidazole-4,6,7-D3) (Standard) is a reference standard of Omeprazole-[D3] Sulfone (Benzimidazole-4,6,7-D3) intended for quantitative analysis, quality control, and related biochemical research applications.

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is an effective and orally active proton pump inhibitor that inhibits H+, K+-ATPase enzyme in gastric parietal cells, reducing acid secretion. It is a promising compound for investigating symptomatic gastroesophageal reflux disease [1] [2] [3].