n acetylneuraminic acid

2,3-Dehydro-2-Deoxy-N-Acetylneuraminic Acid is a pan-sialidase (neuraminidase, NEU) inhibitor with inhibitory activity against sialidases 1–4, with an IC50 of 43–143 μM, and also exhibits inhibitory activity against various influenza viruses.

4,7,8,9-Tetra-O-acetyl-N-acetylneuraminic acid methyl ester is a biochemical reagent utilized in glycobiology research. Glycobiology examines sugar structures, synthesis, biology, and evolution, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the roles of glycans in biological systems. This field is closely linked to fundamental research, biomedicine, and biotechnology.

N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate is a pharmaceutical intermediate utilized in the synthesis of various active compounds.

N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies have shown that N-Acetylneuraminic acid is biologically useful for neurotransmission, leukocyte extravasation, viral or bacterial infections, and carbohydrate-protein recognition.

X-NeuNAc (5-Bromo-4-chloro-3-indolyl-alpha-D-N-acetylneuraminic acid sodium salt) is a new chromogenic assay substrate of neuraminidase activity in bacterial expression systems.

N-Acetylneuraminic acid-13C is the 13C-labeled form of N-Acetylneuraminic acid. This sialic acid monosaccharide is commonly found on glycoproteins of cell membranes and glycolipids of gangliosides in mammalian cells. It plays a biological role in processes such as neurotransmission, leukocyte vascular extravasation, and viral or bacterial infections.

N-Acetylneuraminic acid-13C-3 is the 13C-labeled form of N-Acetylneuraminic acid. This sialic acid monosaccharide is commonly found on glycoproteins of cell membranes and glycolipids of gangliosides in mammalian cells, playing a biological role in neurotransmission, leukocyte vascular extravasation, and viral or bacterial infection.

N-Acetylneuraminic acid (Standard) is a reference grade N-Acetylneuraminic acid suitable for quantitative analysis, quality control, and biochemical research. N-Acetylneuraminic acid is a naturally occurring nine-carbon sialic acid monosaccharide involved in neurotransmission, leukocyte extravasation, viral or bacterial infection, and carbohydrate-protein recognition.

N-Acetylneuraminic acid 2,4,7,8,9-pentaacetate is a reagent used in biochemical reactions.

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) acts as a sialic acid donor in enzyme-catalyzed sialic acid transfers.

Cyclic N-Acetyl-D-mannosamine is a monosaccharide used as a precursor in the chemical or enzymatic synthesis of neuraminic acid found in glycolipids and glycoproteins.N-Acetyl-D-mannosamine is a specific substrate for the synthesis of n -acetylneuraminic acid, an essential precursor for bacterial podoplanar polysialic acid (PA).N-Acetyl-D-mannosamine is used in the synthesis of sialic acid. mannosamine is used in the synthesis of sialic acid. It is also an intermediate in the synthesis of many carbohydrate-derived bioactive compound families and drug candidates.N-Acetyl-D-mannosamine is used in the study of cognitive disorders and aging.

NEU3-IN-2 (compound 963), a derivative of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) and a C9 biphenylcarbamate, functions as an inhibitor of NEU3, a human neuraminidase with four isozymes. This compound exhibits inhibitory activity with a Ki of 0.12 μM and an IC50 of 0.31 μM. It serves as a crucial tool in the exploration of NEU3 isozyme functionality. Additionally, its analogs, featuring an amide and a triazole linker, show selectivity towards NEU1 and NEU4 isozymes, respectively.

Colominic acid sodium salt is an N-acetylneuraminic acid homopolymer produced by Escherichia coli, used to study the process of protein polysialylation and exhibiting antibacterial activity.

N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)), a class I aldolase frequently utilized in biochemical research, catalyzes the reversible condensation of pyruvate and N-acetyl-d-mannosamine (ManNAc), producing N-acetylneuraminic acid (Neu5Ac) [1].

N-Acetyl-D-mannosamine-15N is the 15N-labeled version of N-Acetyl-D-mannosamine (ManNAc). This compound serves as an essential precursor for N-acetylneuraminic acid (NeuAc) and acts as a specific monomer in bacterial capsular poly(sialic acid) [PA]. N-Acetyl-D-mannosamine (ManNAc) is metabolized by GNE and GlcNAc 2-epimerase (renin-binding protein, RnBP) into ManNAc-6-phosphate and GlcN.

N-Acetyl-D-mannosamine-13C is the carbon-13 labeled version of N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is a critical precursor to N-acetylneuraminic acid (NeuAc) and plays a role as a specific monomer of bacterial capsular polysialic acid (PA). It is metabolized into ManNAc-6-phosphate and GlcN through the actions of GNE and GlcNAc 2-epimerase (renin-binding protein, RnBP).

Sialic acid aldolase (Pm NaNa) (EC 4.1.3.3) is a type I aldolase that catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) to produce pyruvate and N-acetyl-D-mannosamine (ManNAc), with the equilibrium favoring the cleavage of Neu5Ac.

ST3 beta-Gal alpha-2,3-Sialyltransferase 6 (EC:2.4.99., ST3GAL6; SIAT10, Type 2 lactosamine alpha-2,3-sialyltransferase) is responsible for transferring sialic acid from activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to N- or O-linked glycans on glycoproteins. This enzyme plays a significant role in cancer.

ST6Sialyltransferase1 (EC:2.4.3.3, ST6GALNAC1, SIAT7A, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1) connects salivary acid, N-acetylneuraminic acid (NeuAc) ST6Sialyltransferase1 plays a key role in the pathogenesis of cancer by transferring sialic acid, N-acetylneuraminic acid (NeuAc), to O-linked GalNAc residues via an alpha-2,6 linkage.