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Search Results for " mitogenic "

12

Compounds

Cat No. Product Name Synonyms Targets
T8461 SKI V Apoptosis , PI3K , S1P Receptor
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity
T13518 5α-Pregnane-3β,6α-diol-20-one Others
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation.
T20879 Tacrolimus monohydrate FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T73552 BPDA2
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and ce...
T71084 Epiderstatin
Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.
T80866 VIP(Guinea pig) TFA Vasoactive Intestinal Peptide, guinea pig TFA
Vasoactive Intestinal Peptide (VIP) Guinea pig TFA, a trophic and mitogenic factor, promotes growth in cultured whole embryos and acts as a gastrointestinal hormone, while also indicating potential neurotransmitter funct...
T37423 Reveromycin D
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μ...
T37052 Tetranactin
Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold g...
T38044 Reveromycin B
Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50 = 6 μg/ml) and exhibits pH-dependent antifungal activity against...
TP2018 GIP, human GIP (human)
Potent insulinotropic hormone synthesized by duodenal K-cells. High affinity GIP receptor agonist (EC50 = 0.81 nM) that inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. Al...
T37008 Reveromycin A
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip...
T76379 Myelopeptide-2
Myelopeptide-2, a peptide isolated from the supernatant of porcine bone marrow cell cultures, can restore the mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. It ...
TargetMol