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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8461 | SKI V | Apoptosis , PI3K , S1P Receptor | |
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity | |||
T13518 | 5α-Pregnane-3β,6α-diol-20-one | Others | |
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation. | |||
T20879 | Tacrolimus monohydrate | FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 | Phosphatase , Others , Antibacterial , Antibiotic , Autophagy |
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi... | |||
T73552 | BPDA2 | ||
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and ce... | |||
T71084 | Epiderstatin | ||
Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor. | |||
T80866 | VIP(Guinea pig) TFA | Vasoactive Intestinal Peptide, guinea pig TFA | |
Vasoactive Intestinal Peptide (VIP) Guinea pig TFA, a trophic and mitogenic factor, promotes growth in cultured whole embryos and acts as a gastrointestinal hormone, while also indicating potential neurotransmitter funct... | |||
T37423 | Reveromycin D | ||
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μ... | |||
T37052 | Tetranactin | ||
Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold g... | |||
T38044 | Reveromycin B | ||
Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50 = 6 μg/ml) and exhibits pH-dependent antifungal activity against... | |||
TP2018 | GIP, human | GIP (human) | |
Potent insulinotropic hormone synthesized by duodenal K-cells. High affinity GIP receptor agonist (EC50 = 0.81 nM) that inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. Al... | |||
T37008 | Reveromycin A | ||
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip... | |||
T76379 | Myelopeptide-2 | ||
Myelopeptide-2, a peptide isolated from the supernatant of porcine bone marrow cell cultures, can restore the mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. It ... |