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Search Results for " mechanism "

Targets

335

Compounds

89

Natural Products

279

Recombinant Proteins

30

Libraries

Cat No. Product Name Synonyms Targets
T5399 GeA-69 PARP
GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).
T14364 AZ-Dyrk1B-33 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine DYRK
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
T2320 Indacaterol Adrenergic Receptor
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.
T0990 Droperidol NSC 169874,Dehydrobenzperidol Dopamine Receptor
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.
T1096 Milrinone Win 47203 PDE
Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.
T1565 Deferiprone Deferidone,CP20 Others , HCV Protease , Ferroptosis , UGT
Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
T21017 5'-Amino-5'-deoxyadenosine 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo Apoptosis , Adenosine Receptor
5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ...
T2552 Succimer DMSA,Dimercaptosuccinic acid,meso-2,3-dimercaptosuccinic acid Others
Succimer (Dimercaptosuccinic acid) is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity.
T0692 Allopurinol Zyloric,Zyloprim,Lopurin ROS , Xanthine Oxidase
Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
T0142 Brinzolamide AL-4862 Carbonic Anhydrase
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
T3511 PF-1355 PF-06281355,PF 06281355,ZINC205721785 Glutathione Peroxidase
PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
T2411 Luliconazole NND 502 Antibiotic , Antifungal
Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.
T1570 Telmisartan BIBR 277 RAAS , Autophagy
Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
T9122 XL177A DUB
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
T4661 PKG drug G1 PKA
PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
T1463 Ramelteon TAK-375 Melatonin Receptor , MT Receptor
Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.
T3591 URB602 Lipase , Antibacterial
URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.
T5471 GUANABENZ Adrenergic Receptor
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.
T0462 Cilostazol OPC 21,OPC 13013 PDE , Autophagy
Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.
T1615 Irbesartan SR-47436,BMS-186295 Apoptosis , RAAS
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T0466 Celecoxib SC 58635 COX
Celecoxib (SC 58635) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as a Cyclooxygenase Inhibitor.
T0476 Spironolactone SC9420,Abbolactone Glucocorticoid Receptor , Androgen Receptor , Autophagy
Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.
TNU0022 6-Azauridine 6-Azuridine Apoptosis
6-Azauridine (6-Azuridine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.6-Azuridine's anticancer mechanism is ...
T68147 T-900607 Microtubule Associated
T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.
T10459 Banoxantrone dihydrochloride AQ4N dihydrochloride,AZD1689 2HCl NOS
Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.
T0826 Meloxicam Movalis,Mobic,Metacam Apoptosis , COX , Autophagy
Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxicam is Nonsteroidal Anti-inflammatory Compounds.
T0293 Metyrapone NSC-25265,Su-4885 Others , P450 , Dehydrogenase , Autophagy
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
T2550 Tolmetin Tolectin COX
Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification of tolmetin is Nonsteroidal Anti-inflammatory Compounds.
T1789 Obeticholic Acid INT-747,6-Ethylchenodeoxycholic acid,6-ECDCA FXR , Autophagy
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist.
T0686 Orlistat Ro-18-0647,Tetrahydrolipstatin Apoptosis , Others , Fatty Acid Synthase
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.
T8468 CIL62 Caspase
CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].
T1280 Nepafenac AL 6515,AHR 9434 COX
Nepafenac (AHR 9434) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of nepafenac is as a Cyclooxygenase Inhibitor. The chemical classification of nepafenac is Nonsteroidal Anti-inflammatory Compounds.
T1646 Famciclovir BRL 42810 DNA/RNA Synthesis , HSV
Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.
T1102 Mifepristone C-1073,RU486,RU 38486 Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T3158L Harman hydrochloride Harmane hydrochloride(486-84-0 Free base) P450
Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
T1469 Levocetirizine Levocetirizine HCl Histamine Receptor
Levocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist.
T2332 Elvitegravir GS-9137,EVG,D06677,JTK-303 HIV Protease
Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.
T1587 Exemestane EXE,FCE 24304,PNU155971 Aromatase
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
T40423 L48H37
L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio...
T12777 RTC-5 TRC-382 EGFR
RTC-5 (TRC-382) (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties. It exhibits considerable effectiveness against an EGFR-driven cancer xenograft model. The m...
T6200 Ledipasvir GS-5885 HCV Protease , SARS-CoV
Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor. The mechanism of action of ledipasvir is as a P-Glycoprotein Inhibitor, and Breast Cancer Resistance Protein Inhibitor.
TNU0977 4-Thiothymidine Apoptosis
4-Thiothymidine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.The anticancer mechanism of 4-Thiothymidine is de...
T0885 Sulfamethoxazole Ro 4-2130,STX 608 Antibacterial , Antibiotic , Autophagy
Sulfamethoxazole (STX 608) is a Sulfonamide Antimicrobial. The mechanism of action of sulfamethoxazole is as a Cytochrome P450 2C9 Inhibitor. The chemical classification of sulfamethoxazole is Sulfonamides.
T7108 Omberacetam SGS-111,Noopept,GVS-111 Others , iGluR
Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.
T13789 N-dodecanoyl-L-Homoserine lactone C12-HSL Others
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.
T7124 Dinotefuran MTI-446 Others , AChR , Parasite
Dinotefuran (MTI-446) is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves disruption of the insect's nerv...
T0708 Oxaprozin Oxaprozinum,Wy21743 NF-κB , COX
Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...
T21578 NSC 66811 Mdm2
NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53...
T1057 Azilsartan TAK-536 RAAS
Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect of azilsartan is by means of Decreased Blood Pres...
T19675 SM360320 CL-087,SM 360320,CL 087,1V136,SM-360320,CL087 TLR
SM360320 (CL-087) is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for ...

Compounds

GeA-69
T5399
Synonym:
Target: PARP
AZ-Dyrk1B-33
T14364
Synonym: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
Target: DYRK
Indacaterol
T2320
Synonym:
Target: Adrenergic Receptor
Droperidol
T0990
Synonym: NSC 169874,Dehydrobenzperidol
Target: Dopamine Receptor
Milrinone
T1096
Synonym: Win 47203
Target: PDE
Deferiprone
T1565
Synonym: Deferidone,CP20
Target: Others, HCV Protease, Ferroptosis, UGT
5'-Amino-5'-deoxyadenosine
T21017
Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo
Target: Apoptosis, Adenosine Receptor
Succimer
T2552
Synonym: DMSA,Dimercaptosuccinic acid,meso-2,3-dimercaptosuccinic acid
Target: Others
Allopurinol
T0692
Synonym: Zyloric,Zyloprim,Lopurin
Target: ROS, Xanthine Oxidase
Brinzolamide
T0142
Synonym: AL-4862
Target: Carbonic Anhydrase
PF-1355
T3511
Synonym: PF-06281355,PF 06281355,ZINC205721785
Target: Glutathione Peroxidase
Luliconazole
T2411
Synonym: NND 502
Target: Antibiotic, Antifungal
Telmisartan
T1570
Synonym: BIBR 277
Target: RAAS, Autophagy
XL177A
T9122
Synonym:
Target: DUB
PKG drug G1
T4661
Synonym:
Target: PKA
Ramelteon
T1463
Synonym: TAK-375
Target: Melatonin Receptor, MT Receptor
URB602
T3591
Synonym:
Target: Lipase, Antibacterial
GUANABENZ
T5471
Synonym:
Target: Adrenergic Receptor
Cilostazol
T0462
Synonym: OPC 21,OPC 13013
Target: PDE, Autophagy
Irbesartan
T1615
Synonym: SR-47436,BMS-186295
Target: Apoptosis, RAAS
Celecoxib
T0466
Synonym: SC 58635
Target: COX
Spironolactone
T0476
Synonym: SC9420,Abbolactone
Target: Glucocorticoid Receptor, Androgen Receptor, Autophagy
6-Azauridine
TNU0022
Synonym: 6-Azuridine
Target: Apoptosis
T-900607
T68147
Synonym:
Target: Microtubule Associated
Banoxantrone dihydrochloride
T10459
Synonym: AQ4N dihydrochloride,AZD1689 2HCl
Target: NOS
Meloxicam
T0826
Synonym: Movalis,Mobic,Metacam
Target: Apoptosis, COX, Autophagy
Metyrapone
T0293
Synonym: NSC-25265,Su-4885
Target: Others, P450, Dehydrogenase, Autophagy
Tolmetin
T2550
Synonym: Tolectin
Target: COX
Obeticholic Acid
T1789
Synonym: INT-747,6-Ethylchenodeoxycholic acid,6-ECDCA
Target: FXR, Autophagy
Orlistat
T0686
Synonym: Ro-18-0647,Tetrahydrolipstatin
Target: Apoptosis, Others, Fatty Acid Synthase
CIL62
T8468
Synonym:
Target: Caspase
Nepafenac
T1280
Synonym: AL 6515,AHR 9434
Target: COX
Famciclovir
T1646
Synonym: BRL 42810
Target: DNA/RNA Synthesis, HSV
Mifepristone
T1102
Synonym: C-1073,RU486,RU 38486
Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, NO Synthase, Autophagy
Harman hydrochloride
T3158L
Synonym: Harmane hydrochloride(486-84-0 Free base)
Target: P450
Levocetirizine
T1469
Synonym: Levocetirizine HCl
Target: Histamine Receptor
Elvitegravir
T2332
Synonym: GS-9137,EVG,D06677,JTK-303
Target: HIV Protease
Exemestane
T1587
Synonym: EXE,FCE 24304,PNU155971
Target: Aromatase
L48H37
T40423
Synonym:
Target:
RTC-5
T12777
Synonym: TRC-382
Target: EGFR
Ledipasvir
T6200
Synonym: GS-5885
Target: HCV Protease, SARS-CoV
4-Thiothymidine
TNU0977
Synonym:
Target: Apoptosis
Sulfamethoxazole
T0885
Synonym: Ro 4-2130,STX 608
Target: Antibacterial, Antibiotic, Autophagy
Omberacetam
T7108
Synonym: SGS-111,Noopept,GVS-111
Target: Others, iGluR
N-dodecanoyl-L-Homoserine lactone
T13789
Synonym: C12-HSL
Target: Others
Dinotefuran
T7124
Synonym: MTI-446
Target: Others, AChR, Parasite
Oxaprozin
T0708
Synonym: Oxaprozinum,Wy21743
Target: NF-κB, COX
NSC 66811
T21578
Synonym:
Target: Mdm2
Azilsartan
T1057
Synonym: TAK-536
Target: RAAS
SM360320
T19675
Synonym: CL-087,SM 360320,CL 087,1V136,SM-360320,CL087
Target: TLR
1 2 3 4 5 6 7
Cat No. Product Name Synonyms Targets
T3817 Darutigenol Others
Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.
T3S1319 (+)-Magnoflorine Escholin,Magnoflorine,Thalictrin,Escholine Others , Antifungal
(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...
TN7068 Sinomenine N-oxide Others
Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine.
T3S0289 Araloside X Calcium Channel
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox...
T6S1894 Linderane P450
1. Linderane was characterized as a mechanism-based inactivator of CYP2C9.
TN1295 5-O-Caffeoylshikimic acid IL Receptor , TNF , NO Synthase
5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.
T1080 2-Aminoethanethiol 2-Mercaptoethylamine,β-Mercaptoethylamine,β-MEA,Cysteamine Apoptosis , Others , Reactive Oxygen Species , Cysteine Protease , Somatostatin , Endogenous Metabolite , Autophagy
2-Aminoethanethiol (Cysteamine) is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T7924 8-Bromoguanosine Others
8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.
T6S0413 Pectolinarigenin Pectolinaringenin Others , Lipoxygenase , COX
1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in ...
TN6988 Pterine-6-carboxylic acid 6-Carboxypterin DNA , PDE
Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mechanism of UVA breaking DNA structure.
T0759 Monobenzone Benoquin Tyrosinase
Monobenzone (Benoquin) is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone is by means of Depigmenting Activity.
T1590 Letrozole CGS 20267 Aromatase , Autophagy
Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
T3806 Kaempferide Kaempferol 4'-O-methyl ether,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Influenza Virus , Antibacterial , Autophagy
kaempferide (4'-Methylkaempferol) inhibits the proliferation of native and estrogen receptor beta overexpressing colon cancer cells through a mechanism not mediated by ligand binding dependent estrogen receptor activatio...
T7468 (-​)​-​α-​Terpineol α-Terpineol Others
(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway
T0501 Mequinol 4-Hydroxyanisole,Leucobasal,4-Methoxyphenol Others
Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosina...
T3S1692 Octahydrocurcumin Anti-infection , NF-κB , Reactive Oxygen Species , ROS
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...
TN6891 1-Hexanol hexan-1-ol Others
1-Hexanol (hexan-1-ol) is a natural product.1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[1]. 1-Hexanol uncouples mitochondrial respiration b...
T5S0734 Desmethoxyyangonin Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain Others , Monoamine Oxidase
1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...
TN1006 Tirucallol NOS , NO Synthase , Prostaglandin Receptor
Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration.
T1153 Trimethoprim NIH 204,BW 56-72,NSC-106568 DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra...
T0983 Penicillamine d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine Antibiotic
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...
T3S1641 Esculentoside H TNF , NF-κB , JNK
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.
T1658 Selenomethionine DL-Selenomethionine,Seleno-DL-methionine Amino Acids and Derivatives , Endogenous Metabolite , Autophagy
DL-Selenomethionine (Seleno-DL-methionine) is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methion...
T3836 Eudesmin MAPK , S6 Kinase
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...
T3404 Cucurbitacin B Cuc B,DATISCACIN,Amarine Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh...
T5254 Glycodeoxycholate Sodium Sodium glycyldeoxycholate,Sodium glycodeoxycholate,Glycodeoxycholic acid sodium salt Others , Endogenous Metabolite
Glycodeoxycholate Sodium (Glycodeoxycholic acid sodium salt) induces Apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes ex...
TNU0052 Nebularine 9-(beta-D-Ribofuranosyl)-9H-purine Apoptosis
Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebulari...
T3717 Hinokitiol 4-Isopropyltropolone,β-thujaplicin DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
T3030 L-Sophoridine Sophoridine,Matridin-15-one Others
L-Sophoridine (Matridin-15-one) , a natural product obtained from medicinal plants, which has a variety of pharmacological effects, including anti-Y effects, and selectively induces apoptotic cell death in a variety of h...
TN1065 Hirsutine Apoptosis
Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti...
T0562 Protocatechuic acid 3, 4-Dihydroxybenzoic acid,Protocatechuate,3,4-Dihydroxybenzoic acid Others
Protocatechuic acid (3, 4-Dihydroxybenzoic acid) (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protective agent ...
T6S1665 Irisflorentin Others , NO Synthase
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan...
T1165 Ethionamide Bayer 5312,2-ethylthioisonicotinamide,Ethinamide Dehydrogenase , CAT , Antibacterial , Antibiotic
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthes...
T2S2043 Dracorhodin perchlorate Dracorhodin perochlorate,Dracohodin perochlorate Apoptosis , Others
Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate...
T6S2227 Spinosin Flavoayamenin Others
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...
T0884 1-Docosanol Behenic alcohol,Behenyl alcohol,n-Docosanol,Docosanol Antifection , HSV
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex viru...
T3776 Rhapontigenin Protigenin P450 , Antibacterial , Antifungal
Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. R...
TN3466 Atherosperminine cAMP , Calcium Channel , AChR , Parasite
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with t...
T4S0867 Pogostone DHELWANGIN Apoptosis , Antibacterial , Autophagy
1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by dire...
T4971 5'-DEOXYADENOSINE 5′-dAdo Endogenous Metabolite
5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long be...
T7032 Eupatorin Others , P450
Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is ...
T2A2498 L-Lysine Aminutrin,Lysine Acid,lysine Virus Protease , Endogenous Metabolite , Antifection
L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats, fish, and dairy products. Lysine seems to be active again...
T0186 Docetaxel trihydrate RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate Apoptosis , BCL , Microtubule Associated
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor i...
T3895 Polyphyllin I Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...
T2915 Bardoxolone RTA 401,CDDO Others , Nrf2
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...
T2966 Beta-Sitosterol Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost Apoptosis , Lipase , Endogenous Metabolite
Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol foun...
T3S1553 Trans-Cinnamaldehyde Cinnamaldehyde,Cinnamic aldehyde,Cinnamal,Phenylacrolein COX , Endogenous Metabolite
1. trans-Cinnamaldehyde (Phenylacrolein) exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. 2. Cinnamic aldehyde induces apoptosis of CML cells...
T5S0661 Koumine Others
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...
T1719 Bufalin ATPase
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
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Natural Products

Darutigenol
T3817
Synonym:
Target: Others
(+)-Magnoflorine
T3S1319
Synonym: Escholin,Magnoflorine,Thalictrin,Escholine
Target: Others, Antifungal
Sinomenine N-oxide
TN7068
Synonym:
Target: Others
Araloside X
T3S0289
Synonym:
Target: Calcium Channel
Linderane
T6S1894
Synonym:
Target: P450
5-O-Caffeoylshikimic acid
TN1295
Synonym:
Target: IL Receptor, TNF, NO Synthase
2-Aminoethanethiol
T1080
Synonym: 2-Mercaptoethylamine,β-Mercaptoethylamine,β-MEA,Cysteamine
Target: Apoptosis, Others, Reactive Oxygen Species, Cysteine Protease, Somatostatin, Endogenous Metabolite, Autophagy
8-Bromoguanosine
T7924
Synonym:
Target: Others
Pectolinarigenin
T6S0413
Synonym: Pectolinaringenin
Target: Others, Lipoxygenase, COX
Pterine-6-carboxylic acid
TN6988
Synonym: 6-Carboxypterin
Target: DNA, PDE
Monobenzone
T0759
Synonym: Benoquin
Target: Tyrosinase
Letrozole
T1590
Synonym: CGS 20267
Target: Aromatase, Autophagy
kaempferide
T3806
Synonym: Kaempferol 4'-O-methyl ether,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Influenza Virus, Antibacterial, Autophagy
(-​)​-​α-​Terpineol
T7468
Synonym: α-Terpineol
Target: Others
Mequinol
T0501
Synonym: 4-Hydroxyanisole,Leucobasal,4-Methoxyphenol
Target: Others
Octahydrocurcumin
T3S1692
Synonym:
Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS
1-Hexanol
TN6891
Synonym: hexan-1-ol
Target: Others
Desmethoxyyangonin
T5S0734
Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain
Target: Others, Monoamine Oxidase
Tirucallol
TN1006
Synonym:
Target: NOS, NO Synthase, Prostaglandin Receptor
Trimethoprim
T1153
Synonym: NIH 204,BW 56-72,NSC-106568
Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic
Penicillamine
T0983
Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine
Target: Antibiotic
Esculentoside H
T3S1641
Synonym:
Target: TNF, NF-κB, JNK
Selenomethionine
T1658
Synonym: DL-Selenomethionine,Seleno-DL-methionine
Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy
Eudesmin
T3836
Synonym:
Target: MAPK, S6 Kinase
Cucurbitacin B
T3404
Synonym: Cuc B,DATISCACIN,Amarine
Target: Apoptosis, PTEN, Integrin, Endogenous Metabolite, HIF, STAT, Autophagy
Glycodeoxycholate Sodium
T5254
Synonym: Sodium glycyldeoxycholate,Sodium glycodeoxycholate,Glycodeoxycholic acid sodium salt
Target: Others, Endogenous Metabolite
Nebularine
TNU0052
Synonym: 9-(beta-D-Ribofuranosyl)-9H-purine
Target: Apoptosis
Hinokitiol
T3717
Synonym: 4-Isopropyltropolone,β-thujaplicin
Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2
L-Sophoridine
T3030
Synonym: Sophoridine,Matridin-15-one
Target: Others
Hirsutine
TN1065
Synonym:
Target: Apoptosis
Protocatechuic acid
T0562
Synonym: 3, 4-Dihydroxybenzoic acid,Protocatechuate,3,4-Dihydroxybenzoic acid
Target: Others
Irisflorentin
T6S1665
Synonym:
Target: Others, NO Synthase
Ethionamide
T1165
Synonym: Bayer 5312,2-ethylthioisonicotinamide,Ethinamide
Target: Dehydrogenase, CAT, Antibacterial, Antibiotic
Dracorhodin perchlorate
T2S2043
Synonym: Dracorhodin perochlorate,Dracohodin perochlorate
Target: Apoptosis, Others
Spinosin
T6S2227
Synonym: Flavoayamenin
Target: Others
1-Docosanol
T0884
Synonym: Behenic alcohol,Behenyl alcohol,n-Docosanol,Docosanol
Target: Antifection, HSV
Rhapontigenin
T3776
Synonym: Protigenin
Target: P450, Antibacterial, Antifungal
Atherosperminine
TN3466
Synonym:
Target: cAMP, Calcium Channel, AChR, Parasite
Pogostone
T4S0867
Synonym: DHELWANGIN
Target: Apoptosis, Antibacterial, Autophagy
5'-DEOXYADENOSINE
T4971
Synonym: 5′-dAdo
Target: Endogenous Metabolite
Eupatorin
T7032
Synonym:
Target: Others, P450
L-Lysine
T2A2498
Synonym: Aminutrin,Lysine Acid,lysine
Target: Virus Protease, Endogenous Metabolite, Antifection
Docetaxel trihydrate
T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate
Target: Apoptosis, BCL, Microtubule Associated
Polyphyllin I
T3895
Synonym:
Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy
Bardoxolone
T2915
Synonym: RTA 401,CDDO
Target: Others, Nrf2
Beta-Sitosterol
T2966
Synonym: Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost
Target: Apoptosis, Lipase, Endogenous Metabolite
trans-Cinnamaldehyde
T3S1553
Synonym: Cinnamaldehyde,Cinnamic aldehyde,Cinnamal,Phenylacrolein
Target: COX, Endogenous Metabolite
Koumine
T5S0661
Synonym:
Target: Others
Bufalin
T1719
Synonym:
Target: ATPase
Prunetin
T4S0878
Synonym: Prunusetin
Target: ERK, Dehydrogenase, NF-κB

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00005 FGF-8a Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-06986 FGF-8b Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-01369 AGRP Protein, Human, Recombinant (His) Human HEK293
Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ...
TMPY-05717 Integrin alpha V beta 8 Protein, Human, Recombinant (His) Human HEK293
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto...
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His) Human HEK293
NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-00864 IL-6R Protein, Human, Recombinant (His) Human HEK293
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In...
TMPY-05278 IL-6R Protein, Human, Recombinant (hFc) Human HEK293
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In...
TMPY-01214 IL-6R Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In...
TMPY-01413 Cripto Protein, Human, Recombinant (His) Human HEK293
Cripto/TDGF1 is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hy...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPY-02443 HSP70 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. HSP are abundant and conserved proteins present in all cells. Upo...
TMPY-02030 CD82 Protein, Human, Recombinant (His) Human HEK293
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras...
TMPY-01081 SR-BI/SCARB1 Protein, Human, Recombinant (His) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-05345 TIGIT Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-02096 TACI Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF...
TMPY-01139 PDGFRA Protein, Human, Recombinant (His) Human HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-01477 MMP-2 Protein, Human, Recombinant Human HEK293
Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is de...
TMPY-02669 TIGIT Protein, Mouse, Recombinant (His) Mouse HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-00716 CD89 Protein, Human, Recombinant (His) Human HEK293
FCAR, also called FcαRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This recep...
TMPY-01601 AXL Protein, Human, Recombinant (His) Human HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPY-01483 SLAMF7 Protein, Human, Recombinant (His) Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-00835 IGFBP-3 Protein, Human, Recombinant (His) Human HEK293
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPY-02879 IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) Human E. coli
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-01608 Decorin Protein, Human, Recombinant (His) Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-01870 IL-9 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates...
TMPY-01725 Leptin Receptor Protein, Human, Recombinant (His) Human HEK293
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe...
TMPY-01032 CD299 Protein, Human, Recombinant (hFc) Human HEK293
C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene locate...
TMPY-01186 Argonaute-2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small...
TMPY-02130 Argonaute-2 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small...
TMPY-00731 Cathepsin B Protein, Human, Recombinant (His) Human HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-02591 SDF-1 Protein, Human, Recombinant Human E. coli
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-01474 PAI-1 Protein, Human, Recombinant (His) Human HEK293
Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SerpinE1 and PLANH1, is a secreted glycoprotein that belongs to the serpin family. SerpinE1 is the primary physiologica...
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a) Human E. coli
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-02358 CD98 Protein, Mouse, Recombinant (His) Mouse HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01938 CD98 Protein, Human, Recombinant (His) Human HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-00105 Recombinant Protein G E. coli
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate bindi...
TMPH-02307 Vinculin Protein, Human, Recombinant (GST) Human E. coli
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.
TMPH-00269 GPR52 Protein, Bovine, Recombinant (His & KSI) Bovine E. coli
Data support a completely novel mechanism in which miR-382 targets kallikrein 5 and contributes to the development of renal inner medullary interstitial fibrosis. PMID: 22202692
TMPH-02743 Klk1b5 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Data support a completely novel mechanism in which miR-382 targets kallikrein 5 and contributes to the development of renal inner medullary interstitial fibrosis. PMID: 22202692
TMPK-00958 BTN1A1 Protein, Human, Recombinant (His & Avi) Human HEK293
Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition.
TMPH-03144 SEY1 Protein, Plasmodium knowlesi, Recombinant (His) Plasmodium knowlesi in vitro E. coli expression system
Binds specifically to the neurotoxin saxitoxin. Its physiological role may be to transport or sequester an endogenous organic molecule other than Fe(3+). It may participate in a detoxification mechanism for neutralizing ...
TMPH-02863 LOX Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the ...
TMPK-00810 TPA Protein, Mouse, Recombinant (His) Mouse HEK293
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin...
TMPH-02034 Retinoschisin Protein, Human, Recombinant (His) Human E. coli
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decr...
TMPH-03451 NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) Saccharomyces cerevisiae E. coli
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPH-03483 Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His) Lithobates catesbeiana HEK293
Binds specifically to the neurotoxin saxitoxin. Its physiological role may be to transport or sequester an endogenous organic molecule other than Fe(3+). It may participate in a detoxification mechanism for neutralizing ...
TMPJ-01035 UBE2G2 Protein, Human, Recombinant (GST) Human E. coli
Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60% and 10...
TMPH-03116 IL-4R Protein, Pig, Recombinant (His) Sus scrofa (Pig) E. coli
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
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FGF-8a Protein, Human, Recombinant
TMPY-00005
Species: Human
Expression System: E. coli
FGF-8b Protein, Human, Recombinant
TMPY-06986
Species: Human
Expression System: E. coli
AGRP Protein, Human, Recombinant (His)
TMPY-01369
Species: Human
Expression System: HEK293
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
TMPY-05717
Species: Human
Expression System: HEK293
HNT/NTM Protein, Human, Recombinant (His)
TMPY-00357
Species: Human
Expression System: HEK293
IL-6R Protein, Human, Recombinant (His)
TMPY-00864
Species: Human
Expression System: HEK293
IL-6R Protein, Human, Recombinant (hFc)
TMPY-05278
Species: Human
Expression System: HEK293
IL-6R Protein, Mouse, Recombinant (His)
TMPY-01214
Species: Mouse
Expression System: HEK293
Cripto Protein, Human, Recombinant (His)
TMPY-01413
Species: Human
Expression System: HEK293
HtrA2/Omi Protein, Human, Recombinant (His)
TMPY-02078
Species: Human
Expression System: E. coli
HSP70 Protein, Human, Recombinant (His)
TMPY-02443
Species: Human
Expression System: Baculovirus-Insect Cells
CD82 Protein, Human, Recombinant (His)
TMPY-02030
Species: Human
Expression System: HEK293
SR-BI/SCARB1 Protein, Human, Recombinant (His)
TMPY-01081
Species: Human
Expression System: HEK293
TIGIT Protein, Cynomolgus, Recombinant (hFc)
TMPY-05345
Species: Cynomolgus
Expression System: HEK293
TACI Protein, Human, Recombinant (His)
TMPY-02096
Species: Human
Expression System: HEK293
PDGFRA Protein, Human, Recombinant (His)
TMPY-01139
Species: Human
Expression System: HEK293
MMP-2 Protein, Human, Recombinant
TMPY-01477
Species: Human
Expression System: HEK293
TIGIT Protein, Mouse, Recombinant (His)
TMPY-02669
Species: Mouse
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
CD89 Protein, Human, Recombinant (His)
TMPY-00716
Species: Human
Expression System: HEK293
AXL Protein, Human, Recombinant (His)
TMPY-01601
Species: Human
Expression System: HEK293
SLAMF7 Protein, Human, Recombinant (His)
TMPY-01483
Species: Human
Expression System: HEK293
IGFBP-3 Protein, Human, Recombinant (His)
TMPY-00835
Species: Human
Expression System: HEK293
IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)
TMPY-02879
Species: Human
Expression System: E. coli
Decorin Protein, Human, Recombinant (His)
TMPY-01608
Species: Human
Expression System: HEK293
IL-9 Protein, Human, Recombinant (His)
TMPY-01870
Species: Human
Expression System: Baculovirus-Insect Cells
Leptin Receptor Protein, Human, Recombinant (His)
TMPY-01725
Species: Human
Expression System: HEK293
CD299 Protein, Human, Recombinant (hFc)
TMPY-01032
Species: Human
Expression System: HEK293
Argonaute-2 Protein, Human, Recombinant (His)
TMPY-01186
Species: Human
Expression System: Baculovirus-Insect Cells
Argonaute-2 Protein, Mouse, Recombinant (His)
TMPY-02130
Species: Mouse
Expression System: Baculovirus-Insect Cells
Cathepsin B Protein, Human, Recombinant (His)
TMPY-00731
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant
TMPY-02591
Species: Human
Expression System: E. coli
PAI-1 Protein, Human, Recombinant (His)
TMPY-01474
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (isoform a)
TMPY-02820
Species: Human
Expression System: E. coli
CD98 Protein, Mouse, Recombinant (His)
TMPY-02358
Species: Mouse
Expression System: HEK293
CD98 Protein, Human, Recombinant (His)
TMPY-01938
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
Recombinant Protein G
TMPY-00105
Species:
Expression System: E. coli
Vinculin Protein, Human, Recombinant (GST)
TMPH-02307
Species: Human
Expression System: E. coli
GPR52 Protein, Bovine, Recombinant (His & KSI)
TMPH-00269
Species: Bovine
Expression System: E. coli
Klk1b5 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02743
Species: Mouse
Expression System: E. coli
BTN1A1 Protein, Human, Recombinant (His & Avi)
TMPK-00958
Species: Human
Expression System: HEK293
SEY1 Protein, Plasmodium knowlesi, Recombinant (His)
TMPH-03144
Species: Plasmodium knowlesi
Expression System: in vitro E. coli expression system
LOX Protein, Mouse, Recombinant (His & Myc)
TMPH-02863
Species: Mouse
Expression System: Baculovirus
tPA Protein, Mouse, Recombinant (His)
TMPK-00810
Species: Mouse
Expression System: HEK293
Retinoschisin Protein, Human, Recombinant (His)
TMPH-02034
Species: Human
Expression System: E. coli
NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)
TMPH-03451
Species: Saccharomyces cerevisiae
Expression System: E. coli
Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His)
TMPH-03483
Species: Lithobates catesbeiana
Expression System: HEK293
UBE2G2 Protein, Human, Recombinant (GST)
TMPJ-01035
Species: Human
Expression System: E. coli
IL-4R Protein, Pig, Recombinant (His)
TMPH-03116
Species: Sus scrofa (Pig)
Expression System: E. coli
Cat No. Product Name
L4200 FDA-Approved Drug Library

1729 compounds
A unique collection of 1729 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS);
L8710 Cuproptosis Compound Library

411 compounds
TargetMol’s Cuproptosis Compound Library is a collection of 411 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
L9500 Target-Focused Phenotypic Screening Library

1832 compounds
A unique collection of 1832 annotated bioactive compounds with clear targets, suitable for phenotypic screening;
L7500 Coagulation and Anticoagulation Compound Library

154 compounds
A unique collection of 154 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);
L5200 Anti-Metabolism Disease Compound Library

1558 compounds
A unique collection of 1558 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L2190 Anti-Lung Cancer Compound Library

1735 compounds
A unique collection of 1735 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study;
L3400 Clinical Compound Library

3480 compounds
A unique collection of 3480 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS);
L2151 Chemotherapy Drug Library

51 compounds
51 Chemotherapeutic drugs that can be used for high-throughput and high-content screening.
L3200 Autophagy Compound Library

1248 compounds
A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L9600 Peptide Compound Library

800 compounds
800 peptides can be used in peptide drug development and signaling transduction and mechanism study;
L6150 Covalent Natural Product Library

596 compounds
Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.
L7110 Anti-Hypertension Compound Library

719 compounds
719 hypertension-related small molecules for high-throughput and high-content screening.
L2570 Human Metabolite Library

4532 compounds
A unique collection of 4532 human metabolites for high-throughput, high-content screening.
L4000 Bioactive Compound Library

14590 compounds
A collection of 14590 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;
L6810 Traditional Chinese Medicine Monomer Library

2688 compounds
A unique collection of 2688 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism
L1110 Microtubule-Targeted Compound Library

155 compounds
A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS;
L2501 Human Endogenous Metabolite Compound Library Plus

1300 compounds
A unique collection of 1300 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.
L2610 Neurotransmitter Receptor Compound Library

1513 compounds
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;
L2510 Lipid Metabolism Compound Library

496 compounds
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L6120 Flavonoid Natural Product Library

477 compounds
A unique collection of 477 flavonoids can be used for high throughput and high content screening;
L7100 Anti-Obesity Compound Library

2286 compounds
A unique collection of 2286 anti-obesity compounds for high throughput and high content screening;
L6210 Tibetan medicine Compound Library

754 compounds
A collection of 754 natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening.
L6820 Tobacco Monomer Library

750 compounds
A unique collection of 750 tobacco monomer compounds for high throughput screening and high content screening;
L9300 Macrocyclic Compound Library

216 compounds
216 macrocyclic compounds of known activity for high-throughput, high-content screening;
L8700 Ferroptosis Compound Library

800 compounds
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study;
L6710 Anti-Inflammatory Traditional Chinese Medicine Compound Library

1260 compounds
A collection of 1260 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study;
L2191 Anti-Breast Cancer Compound Library

1965 compounds
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;
L8500 HIF-1 Signaling Pathway Compound Library

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
L9410 Covalent Inhibitor Library

1949 compounds
A unique collection of 1949 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.

Libraries

FDA-Approved Drug Library
L4200
Compounds: 1729
Cuproptosis Compound Library
L8710
Compounds: 411
Target-Focused Phenotypic Screening Library
L9500
Compounds: 1832
Coagulation and Anticoagulation Compound Library
L7500
Compounds: 154
Anti-Metabolism Disease Compound Library
L5200
Compounds: 1558
Pyroptosis Compound Library
L8720
Compounds: 1077
Anti-Lung Cancer Compound Library
L2190
Compounds: 1735
Clinical Compound Library
L3400
Compounds: 3480
Chemotherapy Drug Library
L2151
Compounds: 51
Autophagy Compound Library
L3200
Compounds: 1248
Peptide Compound Library
L9600
Compounds: 800
Covalent Natural Product Library
L6150
Compounds: 596
Anti-Hypertension Compound Library
L7110
Compounds: 719
Human Metabolite Library
L2570
Compounds: 4532
Bioactive Compound Library
L4000
Compounds: 14590
Traditional Chinese Medicine Monomer Library
L6810
Compounds: 2688
Microtubule-Targeted Compound Library
L1110
Compounds: 155
Human Endogenous Metabolite Compound Library Plus
L2501
Compounds: 1300
Neurotransmitter Receptor Compound Library
L2610
Compounds: 1513
Lipid Metabolism Compound Library
L2510
Compounds: 496
Flavonoid Natural Product Library
L6120
Compounds: 477
Anti-Obesity Compound Library
L7100
Compounds: 2286
Tibetan medicine Compound Library
L6210
Compounds: 754
Tobacco Monomer Library
L6820
Compounds: 750
Macrocyclic Compound Library
L9300
Compounds: 216
Ferroptosis Compound Library
L8700
Compounds: 800
Anti-Inflammatory Traditional Chinese Medicine Compound Library
L6710
Compounds: 1260
Anti-Breast Cancer Compound Library
L2191
Compounds: 1965
HIF-1 Signaling Pathway Compound Library
L8500
Compounds: 1352
Covalent Inhibitor Library
L9410
Compounds: 1949
TargetMol