kanamycin a

Kanamycin A (KanamycinA) is an aminoglycoside antibiotic with antibacterial and antiviral activity that inhibits bacterial and viral replication.

Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.

Amikacin (Amikacina) is a broad-spectrum antibiotic derived from kanamycin.

Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Amikacin sulfate is a broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and ototoxic like the other aminoglycoside antibiotics.

5'-Guanylic acid disodium salt (GMP-5) is a purine ribonucleoside monophosphate. L-Glutamic acid and guanosine monophosphate are biosynthesized from xanthylic acid and L-glutamine via GMP synthase [glutamine-hydrolyzing]. Guanosine triphosphate and guanosine monophosphate are biosynthesized from diguanosine tetraphosphate via bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin, telithromycin, tobramycin, and erythromycin action pathways, and several metabolic disorders including AICA-ribosiduria, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and 2-hydroxyglutric aciduria (D and L form) pathways. Guanosine monophosphate is also found in foods like onion-family vegetables, millet, Chinese water chestnut, and red rice, serving as a potential biomarker for the consumption of these foods.

Amikacin disulfate (BAY-416651 sulfate) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A.

Kanamycin (Kanamycin A) is an orally administered aminoglycoside antibiotic with antibacterial activity, inhibiting bacterial and viral replication by targeting cellular RNA, used for research on tuberculosis and pneumonia.

Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic extracted from Streptomyces kanamyceticus, which inhibits a range of Gram-positive and Gram-negative bacteria.

KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.

CAY10711 is a substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria, including methicillin-resistant S. aureus (MRSA) and stationary-phase bacteria. It displays MIC99 values of 2.9, 11.5, 2.9, and 2.9 μM against S. aureus RN4220, P. aeruginosa PAO1, E. coli ANS1, and MRSA 10082B, respectively. CAY10711 reduces biofilm formation and promotes biofilm dispersal in P. aeruginosa. It is synergistic with kanamycin and has limited adverse effects against mammalian cells or C. elegans development, survival, or reproduction.

Poly(I:C):Kanamycin (1:1) is an equimolar mixture of Poly(I:C) and kanamycin. Poly(I:C) is a synthetic double-stranded RNA analogue and TLR3 agonist commonly used as a vaccine adjuvant; kanamycin enhances Poly(I:C) stability.

Poly(I:C):Kanamycin (1:1) sodium is a complex.Poly(I:C) is a synthetic double-stranded RNA analogue and a TLR3 and RIG-I/MDA5 agonist that enhances immunity and promotes apoptosis in cancer cells.Kanamycin is an antimicrobial agent that is effective against both Gram-negative and positive bacteria which is able to bind the 70S ribosomal subunit.

Kanamycin sulfate, a broad-spectrum antibiotic, is effective for treating severe staphylococcal or Gram-negative bacillary infections. This compound has been linked to ototoxicity [1] [2].

BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gram-positive bacteria, notably including methicillin-resistant S. aureus (MRSA; MICs = 4-64 µg/ml). Furthermore, BING enhances the effectiveness of antibiotics such as ampicillin, amoxicillin, and novobiocin against P. aeruginosa, and it prevents resistance development to kanamycin and ampicillin in E. coli. Notably, its administration in vivo significantly improves survival rates in O. laptipes challenged with E. tarda.

Amikacin-d5 is a deuterated compound of Amikacin. Amikacin has a CAS number of 37517-28-5. Amikacin is a broad-spectrum antibiotic derived from kanamycin.

5'-Guanylic acid disodium salt (Standard) is the standard substance of 5'-Guanylic acid disodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthylic acid and L-glutamine; which is catalyzed by the enzyme GMP synthase [glutamine-hydrolyzing]. In addition, Guanosine triphosphate and guanosine monophosphate can be biosynthesized from diguanosine tetraphosphate; which is catalyzed by the enzyme bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin action pathway, the telithromycin action pathway, the tobramycin action pathway, and the erythromycin action pathway. Guanosine monophosphate is also involved in several metabolic disorders, some of which include the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria (D and L form) pathway. Outside of the human body, guanosine monophosphate can be found in a number of food items such as onion-family vegetables, millet, chinese water chestnut, and red rice. This makes guanosine monophosphate a potential biomarker for the consumption of these food products.

Kasugamycin hydrochloride (Standard) is the standard substance of Kasugamycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Kanamycin disulfate is a reagent used in biochemical reactions.