f33

Roxoperone is a bioactive chemical.

NVP-DFF332 is a HIF-2 inhibitor that can be used in ccRCC related research

8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.

Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders.

Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor.

UCCF-339 is a bioactive chemical.

PF-00337210 is an orally available ATP-competitive inhibitor of the vascular endothelial growth factor receptor type 2 (VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, the VEGFR2 tyrosine kinase inhibitor PF-00337210 selectively binds to VEGFR2 and prevents its phosphorylation which may result in an inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and may eventually cause tumor cell death. VEGFR2, a receptor tyrosine kinase, is frequently overexpressed by a variety of tumor types.

UCD74A HCl is a cell impermeant homolog of UCD38B, inhibitor of uPA (urokinase plasminogen activator).

Gαq/11 protein-IN-1 (compound F33) is a Gαq/11 protein inhibitor with an IC50 value of 9.4 μM, exhibiting anti-tumor activity.