Search Result

Search Results for " damage "

Targets

AChR Parasite

352

Compounds

144

Natural Products

217

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T38272	Thiacloprid		AChR , Parasite
	Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 nM forDrosophilanAChRs and M10 mouse fibroblast cells expres...		AChR , Parasite
T5116	Iprodione		Others , Reactive Oxygen Species , Antifungal
	Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.		Others , Reactive Oxygen Species , Antifungal
T15130	Dilazep dihydrochloride		Others
	Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc...		Others
T8873	Bractoppin		Others , DNA/RNA Synthesis
	Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...		Others , DNA/RNA Synthesis
T9271	RAD51-IN-1		DNA/RNA Synthesis
	Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.		DNA/RNA Synthesis
T4470	Pyridostatin TFA		DNA/RNA Synthesis
	Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.		DNA/RNA Synthesis
T27029	Cjoc42	cjoc 42,cjoc-42
	Cjoc42 is an inhibitor of gankyrin, an ankyrin-repeat oncoprotein whose overexpression has been implicated in the development of many cancer types. cjoc42 prevents the decrease in p53 protein levels normally associated w...
T1767	BMH-21	BMH21	DNA/RNA Synthesis
	BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.		DNA/RNA Synthesis
T1564	Cisplatin	cis-Diaminodichloroplatinum,CDDP	DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy
	Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.
T8320	J14	J-14	Reactive Oxygen Species
	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death		Reactive Oxygen Species
T9232	Mitochondrial fusion promoter M1		Mitochondrial Metabolism
	Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...		Mitochondrial Metabolism
T9497	Niraparib tosylate monohyrate		PARP
	Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting...		PARP
T9849	HQ461		CDK , Molecular Glues
	HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.		CDK , Molecular Glues
T5399	GeA-69		PARP
	GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).		PARP
T21793	CGP 35348		GABA Receptor
	CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.		GABA Receptor
T8492	BO-264		Apoptosis , FGFR
	BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).		Apoptosis , FGFR
T6303	CCT128930		Akt , PKA , S6 Kinase , Autophagy
	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.		Akt , PKA , S6 Kinase , Autophagy
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T14042	4-P-PDOT	4-phenyl-2- propionamidotetralin	Melatonin Receptor , MT Receptor
	4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.		Melatonin Receptor , MT Receptor
T1899	Pyridostatin	RR82,Pyridostatin Trifluoroacetate Salt	DNA/RNA Synthesis
	Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or the telomeres.		DNA/RNA Synthesis
T1677	Montelukast	Singular	Leukotriene Receptor , Lipoxygenase , LTR
	Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury...		Leukotriene Receptor , Lipoxygenase , LTR
T3231	Niraparib	MK-4827	Apoptosis , Others , PARP
	Niraparib (MK-4827) is a PARP inhibitor that selectively inhibits PARP1 and PARP2 (IC50=3.8/2.1 nM). Niraparib has antitumor activity, inhibits DNA damage repair, and induces apoptosis.		Apoptosis , Others , PARP
T7318	Elimusertib	BAY-1895344	ATM/ATR
	Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the target...		ATM/ATR
T9024	OUL35	NSC39047	Others , PARP
	OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.		Others , PARP
T3103	L67	DNA Ligase Inhibitor	DNA , DNA/RNA Synthesis
	L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).		DNA , DNA/RNA Synthesis
T1677L	Montelukast sodium	MK0476	Leukotriene Receptor , LTR
	Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i...		Leukotriene Receptor , LTR
T40192	DGTP	2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
T9776	TRPM4 inhibitor 8		TRP/TRPV Channel
	TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.		TRP/TRPV Channel
T3289	Amifostine	Ethyol,WR2721,Gammaphos	Others , HIF/HIF Prolyl-Hydroxylase
	Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.		Others , HIF/HIF Prolyl-Hydroxylase
T1567	Olanzapine	LY170053	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR
	Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T1640	Ciprofloxacin	Ciproxan,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase , Antibacterial , Antibiotic
	Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.		Topoisomerase , Antibacterial , Antibiotic
T5994	KPT-6566		Others
	KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity.		Others
T6381	Amifostine trihydrate	Ethyol trihydrate,WR2721,Amifostine	Others , HIF/HIF Prolyl-Hydroxylase
	Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.		Others , HIF/HIF Prolyl-Hydroxylase
T0250	Ciprofloxacin monohydrochloride	Bay-09867 (hydrochloride),Ciprofloxacin HCl,Ciprofloxacin hydrochloride	DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
	Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.		DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
T6611	NSC697923	2-[(4-methylphenyl)sulfonyl]-5-nitrofuran	E1/E2/E3 Enzyme
	NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct me...		E1/E2/E3 Enzyme
T6303L	CCT128930 hydrochloride	CCT128930 hydrochloride(885499-61-6 Free base)	Apoptosis , Akt , PKA , mTOR , Autophagy
	CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28...		Apoptosis , Akt , PKA , mTOR , Autophagy
T5045	GSK4112	1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452	Autophagy
	GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.		Autophagy
T3353	Niraparib hydrochloride	MK-4827 hydrochloride,MK-4827 (hydrochloride)	Apoptosis , Others , PARP
	Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of...		Apoptosis , Others , PARP
T6892	Niraparib tosylate	MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate	Apoptosis , PARP
	Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.		Apoptosis , PARP
T14141	AGI-24512		Others , Methionine Adenosyltransferase (MAT)
	AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro.		Others , Methionine Adenosyltransferase (MAT)
T0095	Bendamustine hydrochloride	SDX-105,SDX-105 (Cytostasane) HCl,Bendamustine HCl,EP-3101	Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis
	Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.		Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis
T2410	Nedaplatin	NSC 375101D	DNA/RNA Synthesis
	Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand...		DNA/RNA Synthesis
T23974	DDRI-18	DDRI18,DDRI 18	DNA/RNA Synthesis
	DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joining (NHEJ) DNA repair and enhances the cytotoxicity of antica...		DNA/RNA Synthesis
T12682	Emzadirib	CYT-0851,RAD51-IN-2	DNA/RNA Synthesis
	Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.		DNA/RNA Synthesis
T20109	Cystamine dihydrochloride		Others
	Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.		Others
T31425	Dibenz[a,h]anthracene	CCRIS 208,NSC 22433,AI3-18996,DB(a,h)A	DNA
	Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures.		DNA
T10406	Tuvusertib	M1774,ATR inhibitor 1	Apoptosis , ATM/ATR , Others , Chk
	Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks...		Apoptosis , ATM/ATR , Others , Chk
T70470L	Isomer-CM 352	isomer-1542205-83-3	MMP
	isomer-CM 352 is a metalase inhibitor that can be used to slow brain damage.		MMP
T29071	UR13870	Org 48762-0,POLB 001,UR-13870,UR 13870	p38 MAPK
	UR-13870 (Org 48762-0) is an orally active and selective inhibitor of p38 mitogen-activated protein kinase (MAPK), which prevents bone damage in collagen-induced arthritis in mice.		p38 MAPK
T4575	Chromium picolinate		DNA , p38 MAPK
	Chromium picolinate causes DNA damage and mutation. It is an activator of p38.		DNA , p38 MAPK

Compounds

Thiacloprid

T38272

Synonym:

Target: AChR, Parasite

Iprodione

T5116

Synonym:

Target: Others, Reactive Oxygen Species, Antifungal

Dilazep dihydrochloride

Target: Others, DNA/RNA Synthesis

RAD51-IN-1

T9271

Synonym:

Target: DNA/RNA Synthesis

Pyridostatin TFA

T4470

Synonym:

Target: DNA/RNA Synthesis

cjoc42

T27029

Synonym: cjoc 42,cjoc-42

Target: DNA/RNA Synthesis

Cisplatin

T1564

Synonym: cis-Diaminodichloroplatinum,CDDP

Target: DNA Alkylator/Crosslinker, Ferroptosis, DNA/RNA Synthesis, Autophagy

J14

T8320

Synonym: J-14

Target: Reactive Oxygen Species

Mitochondrial fusion promoter M1

T9232

Synonym:

Target: Mitochondrial Metabolism

Niraparib tosylate monohyrate

Target: CDK, Molecular Glues

Target: GABA Receptor

BO-264

T8492

Synonym:

Target: Apoptosis, FGFR

CCT128930

T6303

Synonym:

Target: Akt, PKA, S6 Kinase, Autophagy

Synonym: 4-phenyl-2- propionamidotetralin

Target: Melatonin Receptor, MT Receptor

Pyridostatin

T1899

Synonym: RR82,Pyridostatin Trifluoroacetate Salt

Target: DNA/RNA Synthesis

Montelukast

T1677

Synonym: Singular

Target: Leukotriene Receptor, Lipoxygenase, LTR

Niraparib

T3231

Synonym: MK-4827

Target: Apoptosis, Others, PARP

Synonym: DNA Ligase Inhibitor

Target: DNA, DNA/RNA Synthesis

Montelukast sodium

T1677L

Synonym: MK0476

Target: Leukotriene Receptor, LTR

dGTP

T40192

Synonym: 2'-Deoxyguanosine-5'-triphosphate

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

TRPM4 inhibitor 8

T9776

Synonym:

Target: TRP/TRPV Channel

Amifostine

T3289

Synonym: Ethyol,WR2721,Gammaphos

Target: Others, HIF/HIF Prolyl-Hydroxylase

Olanzapine

T1567

Synonym: LY170053

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR

Ciprofloxacin

T1640

Synonym: Ciproxan,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

Amifostine trihydrate

T6381

Synonym: Ethyol trihydrate,WR2721,Amifostine

Target: Others, HIF/HIF Prolyl-Hydroxylase

Ciprofloxacin monohydrochloride

T0250

Synonym: Bay-09867 (hydrochloride),Ciprofloxacin HCl,Ciprofloxacin hydrochloride

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

NSC697923

T6611

Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

Target: E1/E2/E3 Enzyme

CCT128930 hydrochloride

T6303L

Synonym: CCT128930 hydrochloride(885499-61-6 Free base)

Target: Apoptosis, Akt, PKA, mTOR, Autophagy

GSK4112

T5045

Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452

Target: Autophagy

Niraparib hydrochloride

T3353

Synonym: MK-4827 hydrochloride,MK-4827 (hydrochloride)

Target: Apoptosis, Others, PARP

Niraparib tosylate

T6892

Synonym: MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate

Target: Apoptosis, PARP

AGI-24512

T14141

Synonym:

Target: Others, Methionine Adenosyltransferase (MAT)

Bendamustine hydrochloride

T0095

Synonym: SDX-105,SDX-105 (Cytostasane) HCl,Bendamustine HCl,EP-3101

Target: Apoptosis, DNA Alkylator/Crosslinker, DNA/RNA Synthesis

Nedaplatin

T2410

Synonym: NSC 375101D

Target: DNA/RNA Synthesis

DDRI-18

T23974

Synonym: DDRI18,DDRI 18

Target: DNA/RNA Synthesis

Emzadirib

T12682

Synonym: CYT-0851,RAD51-IN-2

Target: DNA/RNA Synthesis

Cystamine dihydrochloride

T20109

Synonym:

Target: Others

Dibenz[a,h]anthracene

T31425

Synonym: CCRIS 208,NSC 22433,AI3-18996,DB(a,h)A

Target: DNA

Tuvusertib

T10406

Synonym: M1774,ATR inhibitor 1

Target: Apoptosis, ATM/ATR, Others, Chk

isomer-CM 352

T70470L

Synonym: isomer-1542205-83-3

Target: MMP

UR13870

T29071

Synonym: Org 48762-0,POLB 001,UR-13870,UR 13870

Target: DNA, p38 MAPK

Cat No.	Product Name	Synonyms	Targets
T21498	Phleomycin		DNA/RNA Synthesis , Antibacterial , Antibiotic
	Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T5826	Eupalinolide A		HSP
	Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.		HSP
TN2100	Pratensein		Others , NF-κB
	Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.		Others , NF-κB
T5669	Citric acid monohydrate		Others
	Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...		Others
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T0956	Avermectin B1	Avermectin B1a-Avermectin B1b mixt.,Abamectin	Antibiotic , Parasite , Autophagy
	Avermectin B1 is served as anthelmintic and insecticide.		Antibiotic , Parasite , Autophagy
T20793	Magnesium Lithospermate B	Monomethyl lithospermate B,Lithospermate B	Others
	Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...		Others
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T8130	Ciprofloxacin hydrochloride monohydrate	Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan	Antibacterial , Antibiotic
	Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic,is an antibiotic used to treat a number of bacterial infections		Antibacterial , Antibiotic
T19165	8-Hydroxyguanine	8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine	Endogenous Metabolite
	8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...		Endogenous Metabolite
T8177	Galactinol		Others
	Galactinol Hydrate scavenges hydroxyl free radicals and protects plant cells from oxidative damage.		Others
T2S2003	Phlorizin dihydrate	Phloridzin dihydrate	Others
	1. Phlorizin dihydrate (Phloridzin dihydrate) can significantly inhibit oxidative DNA damage.		Others
T40370	2′-Deoxyadenosine 5′-monophosphate disodium		Endogenous Metabolite
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.		Endogenous Metabolite
TN1698	Glucotropaeolin potassium	Glucotropaeolin,Benzylglucosinolate potassium,Glucotropaeolin Potassium Salt	Others
	Glucotropaeolin potassium (Benzylglucosinolate potassium) is found in cruciferous vegetables and moderately decrease spontaneous DNA damage in animals.		Others
T4035	Khasianine		Others
	Khasianine has strong activity against liver damage induced by CCl4.		Others
T13669	(E)-Cinnamamide	trans-Cinnamamide	Others
	(E)-Cinnamamide (trans-Cinnamamide) is the less active isomer of Cinnamamide which is an effective non-lethal chemical repellent suitable for reducing avian pest damage.		Others
T24711	Ricinine	1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile,Ricinin,Ritsinin	Others
	Ricinine (1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile) is a major alkaloid in Ricinus communis plant with hepatoprotection in CCl4 -induced liver damage.		Others
T4S1725	Galanthamine	Galantamine	Apoptosis , AChE
	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.		Apoptosis , AChE
T3415	Secoisolariciresinol diglucoside	LGM2605	ROS
	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...		ROS
TN1911	Marein		transporter , Akt , HDAC , AMPK
	Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ...		transporter , Akt , HDAC , AMPK
TN1599	Eburicoic acid	Eburicoicacid,MFCD00238594,ZINC4655149	Antioxidant , TNF , NOS , NO Synthase , CCR , Immunology/Inflammation related
	Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in studies about anti-liver cancer.
TN1274	4-Allylcatechol	4-Allylpyrocatechol,Hydroxychavicol	Others
	4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ...		Others
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester	Hederagenin-28-beta-D-glucopyranoside	Others
	Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage.		Others
TQ0154	8-Hydroxyguanosine		Others , Endogenous Metabolite
	8-hydroxyguanosine (8-OHG) is a marker for measuring the rate of oxidative damage to nucleic acids and lipids.		Others , Endogenous Metabolite
T6S0659	Rhynchophylline	Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin	Calcium Channel , NF-κB
	1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in c...		Calcium Channel , NF-κB
T5S2195	Sibiricose A5		Dehydrogenase
	Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia.		Dehydrogenase
T4715	2'-Deoxyguanosine monohydrate	Guanine-2'-deoxyriboside	Others , Endogenous Metabolite
	2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of D...		Others , Endogenous Metabolite
T40834	5-Hydroxymethyl-2'-deoxycytidine	5hmdC	PARP
	5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxy...		PARP
TN6771	Malabaricone B		Others
	Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.		Others
TN2179	Saponarin	Petrocomoside,Saponaretin-7-O-glucoside,Isovitexin-7-O-glucoside	ERK , P450 , NF-κB , AMPK
	Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver damage.		ERK , P450 , NF-κB , AMPK
T3414	Morroniside		Apoptosis , MMP , Pyroptosis
	Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...		Apoptosis , MMP , Pyroptosis
TN1362	Afzelin	Kaempferol-3-O-rhamnoside	PTEN , p38 MAPK , TNF , Mitochondrial Metabolism , Antibacterial , Prostaglandin Receptor , Autophagy
	Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced d...
T0281	Meclocycline sulfosalicylate salt	Meclutin,Mecloderm,Meclan Cream	Antibacterial , Antibiotic
	Meclocycline sulfosalicylate salt (Mecloderm), a tetracycline antibiotic, is used topically (i.e. for skin infections) as it is totally insoluble in water and may damage kidney and liver if given systemically.		Antibacterial , Antibiotic
T4890	3-Nitro-L-tyrosine	3-Nitrotyrosine	Endogenous Metabolite
	3-Nitro-L-tyrosine (3-Nitrotyrosine) is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitric oxide (NO)-depend...		Endogenous Metabolite
TN1043	Keracyanin chloride	Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride	COX
	Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin compound, exhibits antioxidant properties. It effectively prevents the formation of malonaldehyde in oxidized calf thymus DNA, underlining its potentia...		COX
T6S0654	Isocorynoxeine	7-Isocorynoxeine	5-HT Receptor
	1. Isocorynoxeine (7-Isocorynoxeine) shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant neuroprotective effect ...		5-HT Receptor
T2778	(+)-Catechin Hydrate		Antioxidant , COX
	(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems.		Antioxidant , COX
T1695	DL-O-Tyrosine		Amino Acids and Derivatives
	DL-o-Tyrosine is a metabolite of Phenylalanine and is a precursor in the formation of catecholamines. It is used as biomarkers of protein oxidative damage in β-thalassemia.		Amino Acids and Derivatives
T3671	Vitexin-2"-O-rhamnoside	2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside	Others
	Vitexin-2"-O-rhamnoside (Apigenin-8-C-glucoside) is a compound contributes to the protection against H O -mediated oxidative stress damage.		Others
TN7040	Taxifolin 7-O-β-D-glucoside	Taxifolin 7-Glucoside	Others
	Taxifolin 7-O-β-D-glucoside is a flavonoid mainly found in endosperm and involved in defense against pathogens and UV damage.		Others
TN2259	Taurocholic acid	N-Choloyltaurine	TNF , PI3K
	Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathwa...		TNF , PI3K
TN7134	Magnoloside B		Glucosidase
	Magnoloside B, a phenylethanol glycoside from the fruit of Magnolia officinalis, is an α-glucosidase inhibitor with protective effects against free radical-induced oxidative damage and can be used in cancer research.		Glucosidase
T8264	3-Methyl-2-oxovaleric acid		Endogenous Metabolite
	3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin. A neurotoxin cause...		Endogenous Metabolite
T3785	11-oxo-mogroside V	11-oxo Mogroside V	Reactive Oxygen Species
	11-oxo-mogroside V (11-oxo Mogroside V) is a sweet tasting cucurbitane glycoside derivative of mogroside V. It has antioxidant effects against both O2- and OH- and prevents OH-induced DNA damage.		Reactive Oxygen Species
T3662	Eleutheroside E		NF-κB
	Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...		NF-κB
T3008	Lawsone methyl ether	2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone	Apoptosis , Antibacterial , Antifungal
	Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these s...		Apoptosis , Antibacterial , Antifungal
T5S0285	Cistanoside A		Others
	1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat...		Others
T77563	4-Ethylcatechol		DNA
	4-Ethylcatechol is present in red wine and can be extracted from Glechoma longituba (NaKai) Kupr.4-Ethylcatechol induces DNA damage in the presence of Cu(II).4-Ethylcatechol is a potent antiplatelet compound.		DNA
TN1461	(-)-Butin	Butin	Akt , PI3K , Nrf2
	(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...		Akt , PI3K , Nrf2
TN1831	Macranthoside A	Kalopanaxsaponin H	Antioxidant
	Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective...		Antioxidant
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Natural Products

Phleomycin

T21498

Synonym:

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Target: Others, NF-κB

Citric acid monohydrate

Synonym: Citro,Citretten

Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic

Avermectin B1

T0956

Synonym: Avermectin B1a-Avermectin B1b mixt.,Abamectin

Target: Antibiotic, Parasite, Autophagy

Magnesium Lithospermate B

T20793

Synonym: Monomethyl lithospermate B,Lithospermate B

Ciprofloxacin hydrochloride monohydrate

T8130

Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan

Target: Antibacterial, Antibiotic

8-Hydroxyguanine

T19165

Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine

Target: Endogenous Metabolite

Synonym: Phloridzin dihydrate

Target: Others

2′-Deoxyadenosine 5′-monophosphate disodium

T40370

Synonym:

Target: Endogenous Metabolite

Glucotropaeolin potassium

TN1698

Synonym: Glucotropaeolin,Benzylglucosinolate potassium,Glucotropaeolin Potassium Salt

Synonym: trans-Cinnamamide

Target: Others

Ricinine

T24711

Synonym: 1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile,Ricinin,Ritsinin

Target: Apoptosis, AChE

Secoisolariciresinol diglucoside

Target: transporter, Akt, HDAC, AMPK

Eburicoic acid

TN1599

Synonym: Eburicoicacid,MFCD00238594,ZINC4655149

Target: Antioxidant, TNF, NOS, NO Synthase, CCR, Immunology/Inflammation related

4-Allylcatechol

TN1274

Synonym: 4-Allylpyrocatechol,Hydroxychavicol

Target: Others

Hederagenin 28-O-beta-D-glucopyranosyl ester

T3S0208

Synonym: Hederagenin-28-beta-D-glucopyranoside

Target: Others, Endogenous Metabolite

Rhynchophylline

T6S0659

Synonym: Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin

Target: Calcium Channel, NF-κB

Sibiricose A5

T5S2195

Synonym:

Target: Dehydrogenase

2'-Deoxyguanosine monohydrate

T4715

Synonym: Guanine-2'-deoxyriboside

Target: Others, Endogenous Metabolite

5-Hydroxymethyl-2'-deoxycytidine

Synonym: Petrocomoside,Saponaretin-7-O-glucoside,Isovitexin-7-O-glucoside

Target: ERK, P450, NF-κB, AMPK

Morroniside

T3414

Synonym:

Target: Apoptosis, MMP, Pyroptosis

Afzelin

TN1362

Synonym: Kaempferol-3-O-rhamnoside

Target: PTEN, p38 MAPK, TNF, Mitochondrial Metabolism, Antibacterial, Prostaglandin Receptor, Autophagy

Meclocycline sulfosalicylate salt

T0281

Synonym: Meclutin,Mecloderm,Meclan Cream

Target: Antibacterial, Antibiotic

3-Nitro-L-tyrosine

T4890

Synonym: 3-Nitrotyrosine

Target: Endogenous Metabolite

Keracyanin chloride

TN1043

Synonym: Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride

Target: COX

Isocorynoxeine

T6S0654

Synonym: 7-Isocorynoxeine

Target: 5-HT Receptor

(+)-Catechin Hydrate

T2778

Synonym:

Target: Antioxidant, COX

DL-O-Tyrosine

T1695

Synonym:

Target: Amino Acids and Derivatives

Vitexin-2"-O-rhamnoside

T3671

Synonym: 2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside

Target: Others

Taxifolin 7-O-β-D-glucoside

TN7040

Synonym: Taxifolin 7-Glucoside

Target: Others

Taurocholic acid

TN2259

Synonym: N-Choloyltaurine

3-Methyl-2-oxovaleric acid

T8264

Synonym:

Target: Endogenous Metabolite

11-oxo-mogroside V

T3785

Synonym: 11-oxo Mogroside V

Target: Reactive Oxygen Species

Synonym: 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone

Target: Apoptosis, Antibacterial, Antifungal

Target: Akt, PI3K, Nrf2

Macranthoside A

TN1831

Synonym: Kalopanaxsaponin H

Target: Antioxidant

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02150	GADD45A Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulatio...
TMPY-03601	PDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chapero...
TMPJ-00711	GADD45G Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript...
TMPJ-00907	GADD45A Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some ...
TMPY-03655	GADD45G Protein, Human, Recombinant	Human	E. coli
	GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...
TMPH-02641	ECEL1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
TMPJ-00700	GADD45B Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc)	Human	HEK293
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPY-02521	HIST3H2A Protein, Human, Recombinant	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident ...
TMPJ-00090	FGF-9 Protein, Human, Recombinant	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPY-04376	PLK1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase PLK1 / PLK-1, also known as polo-like kinase 1 (PLK-1) or serine / threonine-protein kinase 13 (STPK13), Polo-like kinases (PLKs), is a family of four serine / threonine protein kinases ...
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-01848	HMGB1 Protein, Human, Recombinant (aa 1-215, His)	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-03532	LIF Protein, Human, Recombinant (His)	Human	HEK293
	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04104	LIF Protein, Human, Recombinant	Human	HEK293
	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04278	LIF Protein, Mouse, Recombinant	Mouse	HEK293
	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-03577	Pleiotrophin/PTN Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
TMPJ-01011	FGF-9 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine a...
TMPY-00804	FGF-9 Protein, Human, Recombinant (hFc)	Human	HEK293
	Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell sur...
TMPY-02848	Adiponectin Protein, Human, Recombinant (hFc)	Human	HEK293
	Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t...
TMPY-01188	PARP Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Poly (ADP-ribose) polymerase 1(PRAP1), also known as NAD(+) ADP-ribosyltransferase 1(ADPRT), is a chromatin-associated enzyme that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The ADP-D-ribosyl group of N...
TMPY-05556	Adiponectin Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t...
TMPY-05593	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane ...
TMPY-04580	IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane ...
TMPY-05840	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane ...
TMPY-03290	HGF Protein, Mouse, Recombinant	Mouse	HEK293
	Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ...
TMPY-02327	HGF Protein, Human, Recombinant	Human	CHO
	Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ...
TMPY-00915	Serpin A1 Protein, Human, Recombinant (His)	Human	HEK293
	SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit...
TMPY-01919	MMP-9 Protein, Mouse, Recombinant	Mouse	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-00888	MMP-9 Protein, Human, Recombinant (His)	Human	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-01248	MMP-9 Protein, Human, Recombinant	Human	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-00653	Complement C5 Protein, Human, Recombinant (Complement C5a)	Human	E. coli
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-04902	Complement C5a Protein, Mouse, Recombinant	Mouse	E. coli
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-05057	Complement C5 Protein, Human, Recombinant (His & FLAG)	Human	HEK293
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPH-01296	GPX5 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective syste...
TMPH-00605	CDTB Protein, E. coli, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arres...
TMPH-01091	CHD1L Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catal...
TMPH-02659	FPR2 Protein, Mouse, Recombinant (GST & His & Myc)	Mouse	E. coli
	High affinity receptor for N-formyl-methionyl peptides (FMLP), which are powerful neutrophil chemotactic factors. Stimulates chemotaxis in immune cells to site of infection or tissue damage upon recognition of several li...
TMPY-04681	CHEK2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by CHEK2 gene is a cell cycle checkpoint regulator and putativ...
TMPH-01882	PARP9 Protein, Human, Recombinant (His)	Human	E. coli
	ADP-ribosyltransferase which, in association with E3 ligase DTX3L, plays a role in DNA damage repair and in immune responses including interferon-mediated antiviral defenses. Within the complex, enhances DTX3L E3 ligase ...
TMPH-03100	PMAP-23 Protein, Pig, Recombinant (His & SUMO)	Sus scrofa (Pig)	E. coli
	Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes.
TMPH-02681	GPX7 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
TMPY-04435	CHEK2 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by CHEK2 gene is a cell cycle checkpoint regulator and putativ...
TMPJ-00870	NCK1 Protein, Human, Recombinant (His)	Human	E. coli
	Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, ...
TMPH-01351	FOxM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in t...
TMPH-01350	FOxM1 Protein, Human, Recombinant (GST)	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in t...
TMPH-03452	NDPK Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	Yeast
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPH-03451	NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)	Saccharomyces cerevisiae	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPJ-00990	S100B Protein, Mouse, Recombinant (His)	Mouse	E. coli
	S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an i...
TMPH-01267	RNF13 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair protein...
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GADD45A Protein, Human, Recombinant (His & GST)

TMPY-02150

Species: Human

Expression System: Baculovirus-Insect Cells

PDRG1 Protein, Human, Recombinant (His)

TMPY-03601

Species: Human

Expression System: E. coli

GADD45G Protein, Human, Recombinant (His)

TMPJ-00711

Species: Human

Expression System: E. coli

GADD45A Protein, Human, Recombinant (His)

TMPJ-00907

Species: Human

Expression System: E. coli

GADD45G Protein, Human, Recombinant

TMPY-03655

Species: Human

Expression System: E. coli

ECEL1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02641

Species: Mouse

Expression System: E. coli

GADD45B Protein, Human, Recombinant (His)

TMPJ-00700

Species: Human

Expression System: E. coli

TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

TMPY-02953

Species: Human

Expression System: HEK293

HIST3H2A Protein, Human, Recombinant

TMPY-02521

Species: Human

Expression System: E. coli

FGF-9 Protein, Human, Recombinant

TMPJ-00090

Species: Human

Expression System: E. coli

PLK1 Protein, Human, Recombinant (His)

TMPY-04376

Species: Human

Expression System: Baculovirus-Insect Cells

HMGB1 Protein, Mouse, Recombinant (hFc)

TMPY-02590

Species: Mouse

Expression System: HEK293

HMGB1 Protein, Human, Recombinant (aa 1-215, His)

TMPY-01848

Species: Human

Expression System: HEK293

LIF Protein, Human, Recombinant (His)

TMPY-03532

Species: Human

Expression System: HEK293

LIF Protein, Human, Recombinant

TMPY-04104

Species: Human

Expression System: HEK293

LIF Protein, Mouse, Recombinant

TMPY-04278

Species: Mouse

Expression System: HEK293

Pleiotrophin/PTN Protein, Mouse, Recombinant

TMPY-03577

Species: Mouse

Expression System: Baculovirus-Insect Cells

FGF-9 Protein, Mouse, Recombinant (His)

TMPJ-01011

Species: Mouse

Expression System: E. coli

FGF-9 Protein, Human, Recombinant (hFc)

TMPY-00804

Species: Human

Expression System: HEK293

Adiponectin Protein, Human, Recombinant (hFc)

TMPY-02848

Species: Human

Expression System: HEK293

PARP Protein, Human, Recombinant (His)

TMPY-01188

Species: Human

Expression System: Baculovirus-Insect Cells

Adiponectin Protein, Human, Recombinant (His)

TMPY-05556

Species: Human

Expression System: Baculovirus-Insect Cells

IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05593

Species: Human

Expression System: HEK293

IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)

TMPY-04580

Species: Mouse

Expression System: HEK293

IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)

TMPY-05840

Species: Cynomolgus

Expression System: HEK293

HGF Protein, Mouse, Recombinant

TMPY-03290

Species: Mouse

Expression System: HEK293

HGF Protein, Human, Recombinant

TMPY-02327

Species: Human

Expression System: CHO

Serpin A1 Protein, Human, Recombinant (His)

TMPY-00915

Species: Human

Expression System: HEK293

MMP-9 Protein, Mouse, Recombinant

TMPY-01919

Species: Mouse

Expression System: HEK293

MMP-9 Protein, Human, Recombinant (His)

TMPY-00888

Species: Human

Expression System: HEK293

MMP-9 Protein, Human, Recombinant

TMPY-01248

Species: Human

Expression System: HEK293

Complement C5 Protein, Human, Recombinant (Complement C5a)

TMPY-00653

Species: Human

Expression System: E. coli

Complement C5a Protein, Mouse, Recombinant

TMPY-04902

Species: Mouse

Expression System: E. coli

Complement C5 Protein, Human, Recombinant (His & FLAG)

TMPY-05057

Species: Human

Expression System: HEK293

GPX5 Protein, Human, Recombinant (GST & His)

TMPH-01296

Species: Human

Expression System: E. coli

CDTB Protein, E. coli, Recombinant (His & Myc & SUMO)

TMPH-00605

Species: E. coli

Expression System: E. coli

CHD1L Protein, Human, Recombinant (His & SUMO)

TMPH-01091

Species: Human

Expression System: E. coli

FPR2 Protein, Mouse, Recombinant (GST & His & Myc)

TMPH-02659

Species: Mouse

Expression System: E. coli

CHEK2 Protein, Human, Recombinant (GST)

TMPY-04681

Species: Human

Expression System: Baculovirus-Insect Cells

PARP9 Protein, Human, Recombinant (His)

TMPH-01882

Species: Human

Expression System: E. coli

PMAP-23 Protein, Pig, Recombinant (His & SUMO)

TMPH-03100

Species: Sus scrofa (Pig)

Expression System: E. coli

GPX7 Protein, Mouse, Recombinant (His & Myc)

TMPH-02681

Species: Mouse

Expression System: E. coli

CHEK2 Protein, Mouse, Recombinant (His & GST)

TMPY-04435

Species: Mouse

Expression System: Baculovirus-Insect Cells

NCK1 Protein, Human, Recombinant (His)

TMPJ-00870

Species: Human

Expression System: E. coli

FOxM1 Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01351

Species: Human

Expression System: E. coli

FOxM1 Protein, Human, Recombinant (GST)

TMPH-01350

Species: Human

Expression System: E. coli

NDPK Protein, S. cerevisiae, Recombinant (His)

TMPH-03452

Species: Saccharomyces cerevisiae

Expression System: Yeast

NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)

TMPH-03451

Species: Saccharomyces cerevisiae

Expression System: E. coli

S100B Protein, Mouse, Recombinant (His)

TMPJ-00990

Species: Mouse

Expression System: E. coli

RNF13 Protein, Human, Recombinant (His & Myc)

TMPH-01267

Species: Human

Expression System: E. coli

--------- More ---------

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L3900	DNA Damage & Repair Compound Library	937 compounds
	A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
L3980	DNA Damage and Repair Compound Library Plus	667 compounds
	Well-chosen 667 compounds with unique structures targeting DNA damage & repair;
L2910	Antioxidant Compound Library	1330 compounds
	Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L8200	Anti-Aging Compound Library	3324 compounds
	A unique collection of 3324 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);
L1700	Anti-Viral Compound Library	1040 compounds
	A unique collection of 1040 anti-virus compounds effective for new anti-virus drugs high throughput screening and high content screening;
L3500	Histone Modification Compound Library	480 compounds
	A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
L3200	Autophagy Compound Library	1248 compounds
	A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2150	Anti-Cancer Drug Library	3159 compounds
	A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
L2160	Anti-Cancer Active Compound Library	3250 compounds
	A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L6730	Anti-virus Traditional Chinese Medicine Monomer Library	270 compounds
	A collection of 270 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies.
L2100	Anti-Cancer Compound Library	7360 compounds
	A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L8600	Ubiquitination Compound Library	214 compounds
	A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；
L2120	Anti-Cancer Clinical Compound Library	2614 compounds
	A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L2110	Anti-Cancer Approved Drug Library	1825 compounds
	A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180	Anti-Cancer Compound Library Plus	1468 compounds
	Well-chosen 1468 anti-tumor compounds with unique structures;
L7700	Neural Regeneration Compound Library	529 compounds
	A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;
L2190	Anti-Lung Cancer Compound Library	1735 compounds
	A unique collection of 1735 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study；