d-alanine

Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. D-Alanine ((R)-Alanine) is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

D-Alanine ethyl ester hydrochloride (T66104, CAS 6331-09-5) is a valuable organic compound for life sciences research.

3-Azido-D-alanine hydrochloride, an azido-modified derivative of D-alanine hydrochloride, serves as a reagent in click chemistry labeling research [1].

N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine inhibits the PAICS protein, reducing the accumulation of SAICAR and SAICAr.

3-Azido-D-alanine, a derivative of azido D-alanine (D-alanine), is utilized in click chemistry for labeling purposes.

FMOC-3-azido-D-alanine is a click chemistry reagent containing an azido group.

Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine-CoA (Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine-coenzyme A) is a derivative of coenzyme A.

Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine-CoA (Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine-coenzyme A) is a derivative of coenzyme A.

Meropenem (SM 7338) is a broad-spectrum carbapenem antibiotic administered intravenously for severe bacterial infections caused by sensitive agents. It commonly causes mild, transient aminotransferase elevations and can rarely lead to clinically apparent cholestatic liver injury.

D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.

Fludalanine (MK641), an analogue of D-alanine, irreversiably inactivates racemase and also inhibits synthase. When used in combination with cycloserine, it has been found to be more active against a variety of non-mycobacterium organisms than fludalanine

DL-Alanine (DL-2-Aminopropionic acid) is an amino acid that is a racemic compound of L- and D-alanine.DL-Alanine is often used as a reducing and capping agent in conjunction with aqueous silver nitrate for nanoparticle generation.DL-Alanine is a sweetening agent, and can be grouped with glycine and sodium saccharin.DL-Alanine plays an important role in glucose-alanine cycling between tissues and liver.DL-Alanine can be used to study the chelation of transition metals such as Cu, Zn, and Cd. DL-Alanine plays an important role in the glucose-alanine cycle between tissues and the liver.DL-Alanine can be used to study the chelation of transition metals such as Cu, Zn, and Cd.

Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is a derivative of an amino acid featuring a Boc protecting group. It is utilized in the synthesis of a powerful NMDA receptor glycine site agonist that exhibits specific activity towards the GluN2 subunit.

D-Histidine hydrochloride hydrate is an agent that targets bacterial quorum sensing systems, such as the RhlI/RhlR pathway, to inhibit biofilm formation with antibacterial properties. It acts by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. Additionally, D-Histidine hydrochloride hydrate downregulates quorum sensing-related gene expression, reduces synthesis of virulence factors (such as alginate and protease), and disrupts bacterial membrane stability. This results in inhibiting biofilm formation, promoting the disassembly of mature biofilms, and increasing antibiotic sensitivity. Furthermore, it serves as an efficient catalyst for the salt-induced peptide formation (SIPF) reaction by forming complexes with copper ions (Cu2+), which facilitates the condensation of amino acids to form dipeptides, such as di-alanine and di-lysine.

D-Alanyl-L-alanine is a bioactive chemical.