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Results for "

carcinogenic

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    68
    TargetMol | Inhibitors_Agonists
  • Dye Reagents
    3
    TargetMol | Dye_Reagents
  • Natural Products
    28
    TargetMol | Natural_Products
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    TargetMol | Recombinant_Protein
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    TargetMol | Inhibitors_Agonists
Erastin
T1765571203-78-6
Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations.
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Cytembena
T2711221739-91-3In house
Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.
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6-8 weeks
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Indecainide
Ricainide, Ricainid, Indecainidum, Indecainida, Decabid
T3215574517-78-5In house
Indecainide (Ricainid) is a novel antiarrhythmic compound that is carcinogenic and can be used to study chronic stable ventricular arrhythmias secondary to coronary artery disease or cardiomyopathy.
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6-8 weeks
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MTOB
α-keto-γ-Methylthiobutyric acid sodium salt, MTOB sodium salt, KMBA, 4-methylthio 2-oxobutyric acid sodium salt
T3351951828-97-8In house
MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, leading to cancer stem cell (CSC) growth and self-renewal.
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Cyclamic acid
NSC 220327, Cyclohexylsulfamic acid, Cyclamate
T0941100-88-9
Cyclamic acid (NSC-220327) is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogenic activity (disputed).
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Propoxur
Aprocarb, Propoxure, Baygon
T0976114-26-1
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red blood cells, with mild cholinergic symptoms including blurred vision, nausea, vomiting, sweating, and tachycardia; however, the effects are transient. Chronic (long-term) inhalation exposure has resulted in depressed cholinesterase levels, headaches, vomiting, and nausea in humans. Chronic ingestion studies in animals have reported depressed cholinesterase levels, depressed body weight, effects to the liver and bladder, and a slight increase in neuropathy. No information is available on the reproductive, developmental, or carcinogenic effects of propoxur in humans. Mixed results are available from cancer studies of propoxur in animals. EPA has not classified propoxur for carcinogenicity.
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4-6 weeks
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Hesperidin
Hesperetin 7-rutinoside, Cirantin
T1035520-26-3
Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
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Nicosulfuron
Milagro, Accent, Motivell
T19859111991-09-4
Nicosulfuron (Milagro) is a pesticide that works by inhibiting the acetolactate synthase enzyme. Nicosulfuron has not been found to induce mutagenic or carcinogenic effects. Nicosulfuron is a herbicide to protect corn crops from weeds.
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2,5-Dimethyl-3(2H)-furanone
2,5-Dimethyl-2,3-dihydrofuran-3-one
T2230914400-67-0
2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a non-genotoxic flavoring substance [1].
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Daidzin
NPI-031D, Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside
T2901552-66-9
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
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1-Hydroxyanthraquinone
T37101129-43-1
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
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Dimethyl phthalate
Solvanom, Fermine, Avolin
T3746131-11-3
Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irritation of the eyes, nose, and throat. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of dimethyl phthalate in humans. Animal studies have reported slight effects on growth and on the kidney from chronic oral exposure to the chemical. EPA has classified dimethyl phthalate as a Group D, not classifiable as to human carcinogenicity.
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Hydroxy Dimetridazole
T37514936-05-0
Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected to be carcinogenic and mutagenic to humans. Hydroxy dimetridazole is a metabolite of dimetridazole that may be useful for identifying this nitroimidazole in various agricultural samples through liquid chromatography-tandem mass spectrometry and other methods.
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Methyl eugenol
O-methyleugenol, eugenyl methyl ether, Eugenol Methyl ether, 4-allylveratrole
T3S225993-15-2
1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. 2. Methyleugenol has insecticidal properties. 3. Methyleugenol can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells; indicates that methyleugenol could be useful for the treatment of ischemia inflammation-related diseases. 4. Methyleugenol has cytotoxicity and genotoxicity. 5. Intravenous (i.v.) treatment with methyleugenol (ME) in either anesthetized or conscious rats elicits hypotension, an effect that seems related to an active vascular relaxation rather than withdrawal of sympathetic tone. 6. Methyleugenol has antinociceptive effect on the second phase of formalin-induced pain, may be due to the inhibition of N-methyl-d-aspartic acid (NMDA) receptor-mediated hyperalgesia via GABA(A) receptors. 7. Methyleugenol has elaxant and antispasmodic actions on guinea-pig isolated ileum.
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Auraptene
7-geranyloxycoumarin
T4115495-02-3
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phas
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N-Nitroso-N-methylurea
N-Methyl-N-nitrosourea, Methylnitrosourea, 1-Methyl-1-nitrosourea
T4169684-93-5
N-Nitroso-N-methylurea is a nitrosourea compound with alkylating, carcinogenic and mutagenic properties. It targets a variety of animal organs, causes various cancers and degenerative diseases, and can be used in diazomethane synthesis.
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Ethylmalonic acid
T5279601-75-2
Ethylmalonic acid is potentially toxic, non-carcinogenic, and has been associated with anorexia nervosa and methoxy decarboxylase deficiency.
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AGI-026
AGI-12026, AGI12026, AGI026, AGI 026
T265751446501-77-4
AGI-026 (AGI-12026) is a novel and potent dual inhibitor of the mutant isocitrate dehydrogenase mIDH1 2 with the advantages of oral administration and penetration of the blood-brain barrier, with a drug concentration to plasma concentration ratio (brain plasma ratio) of 1.5 in brain tissue, and the ability to reduce the accumulation of the carcinogenic metabolite d-2-hydroxyglutarate (2-HG), which is used in the study of mIDH gliomas.
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6-8 weeks
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Pirinixic Acid
Wy-14643, NSC 310038
T226950892-23-4
Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, carcinogenic Pirinixic acid is a peroxisome proliferator that activates specific peroxisome proliferator-activated receptors (PPAR).
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8-Hydroxyguanine
8 Hydroxyguanine, 7,8-dihydro-8-oxoguanine, 2-Amino-6,8-dihydroxypurine
T191655614-64-2
8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-Hydroxyguanine is mutagenic and carcinogenic and is commonly used in cancer experiments.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.
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6-8 weeks
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7-Methyladenine
NSC-7857, NSC7857, NSC 7857
T20039935-69-3
7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents.
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4-6 weeks
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Benzidine orange
Polymo Orange GR, Oralith Orange PG, DCC-1802, DCC1802, DCC 1802
T207603520-72-7
Benzidine orange (DCC-1802) shows mutagenic and carcinogenic activity.
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Aflatoxicol
Aflatoxin R0
T1353129611-03-8
Aflatoxin (Aflatoxin R0) is a mutagenic and carcinogenic mycotoxin that is derived from aflatoxin B1 through metabolic processes facilitated by Rhizopus spp.
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Musk tibetene
Musk tibetine
T16160145-39-1
Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell lines. Musk tibetene is a nitro musk compound with carcinogenic activity.
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6-8 weeks
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