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Expression system: HEK293 Cells<br>Length: 7-71, Partial<br>Activity: Not Tested

Expression system: HEK293 Cells<br>Length: 7-71, Partial<br>Activity: ELISA

BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI TNFRSF13B) and BAFF receptor (BAFF R BR3 TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.

Expression system: HEK293 Cells<br>Length: 6-71, Partial<br>Activity: ELISA

Expression system: HEK293 Cells<br>Length: 1-785, Partial<br>Activity: Not Tested

Expression system: Baculovirus Insect Cells<br>Length: 1-781, Partial<br>Activity: Not Tested

Expression system: E. coli<br>Length: 1-277, Full Length<br>Activity: Not Tested

Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.