antidote — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0130	Physostigmine Salicylate		AChR , AChE
	Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean.		AChR , AChE
T39477	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate	Ca-DTPA trisodium salt hydrate	Others
	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Ca-DTPA tris...		Others
T0765	Fomepizole	Antizol-Vet,4-Methylpyrazole,Antizol	P450 , CAT , AChR
	Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that cata...		P450 , CAT , AChR
T20608	3-Benzoylpyridine	3 Benzoylpyridine,Phenyl 3-pyridyl ketone,Pyridine, 3-benzoyl-	Others
	3-Benzoylpyridine (Phenyl 3-pyridyl ketone) is a decomposition product of HGG-12 which is the soman antidote.		Others
T0148	Folinic acid calcium	Wellcovorin,Calcium folinate,Leucovorin Calcium,Folinic acid calcium salt	DNA/RNA Synthesis , Endogenous Metabolite , Antifolate
	Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.		DNA/RNA Synthesis , Endogenous Metabolite , Antifolate
T1396	Bemegride	Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon	GABA Receptor
	Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.		GABA Receptor
T21447	Tolazoline	Priscol,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin	Adrenergic Receptor
	Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse th...		Adrenergic Receptor
T8034	Dimethyl Trisulfide		Others , Endogenous Metabolite
	Dimethyl trisulfide is the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote.		Others , Endogenous Metabolite
T9948	NecroX-7	LC-280126,LC28-0126,LC28 0126	NADPH-oxidase
	NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ...		NADPH-oxidase
T31370	Delparantag	PMX60056,PMX-60056,PMX 60056
	Delparantag( PMX-60056) is a heparins antidote designed to restore coagulation.
T22404	Pralidoxime Iodide	2-PAM	Others
	Pralidoxime Iodide, also named 2-PAM, is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.		Others
T24538	N-Monoacetylcystine	Parvolex,N-Acetylcystine
	N-Monoacetylcystine is a paracetamol poisoning antidote. It is used in the treatment of influenza A virus pandemic.
T69079	Trimedoxime bromide
	Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.
T16372	Obidoxime dichloride		Others
	Obidoxime dichloride, a selective oxime agent, effectively reactivates sarin-inhibited acetylcholinesterase (AChE) and mitigates the acute toxicity associated with sarin exposure. It is also utilized as an antidote for o...		Others
T69472	Edrophonium
	Edrophonium is a rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
T62857	K203
	K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.
T73060	Pralidoxime
	Pralidoxime is a potent antidote for organophosphate poisoning, effectively reactivating acetylcholinesterase (AChE) that has been inhibited by nerve agents. It achieves this reactivation through a direct nucleophilic at...
T61187	BRD4 Inhibitor-17
	BRD4 Inhibitor-17 (Compound 5i) is a highly potent inhibitor of BRD4, exhibiting an impressive IC50 value of 0.33 μM. It fulfills a crucial regulatory function in transcription by effectively modulating the expression of...
T72245	Fomepizole hydrochloride	4-Methylpyrazole hydrochloride
	Fomepizole hydrochloride (4-Methylpyrazole), a potent, orally active inhibitor of cytochrome P450 (CYP2E1) and a competitive inhibitor of alcohol dehydrogenase, prevents the conversion of methanol and ethylene glycol int...