tetrahydroisoquinoline — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T50003	Debrisoquin hydriodide	1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide	Others
	Debrisoquin hydriodide (1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide) has antioxidant, anti-inflammatory and neuroprotective properties. It has also been found to modulate the activity of certain neurotra...		Others
T9970	MGluR3 modulator-1	1-ethyl-3-(morpholin-4-yl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile	GluR
	mGluR3 modulator-1 (1-ethyl-3-(morpholin-4-yl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile) is a positive allosteric modulator of mGluR3 and can be used in studies about the treatment of Parkinson's disease.		GluR
T66649	(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
	(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a useful organic compound for research related to life sciences. The catalog number is T66649 and the CAS number is 118864-75-8.
T60186	(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide		Discoidin Domain Receptor (DDR)
	MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cyto...		Discoidin Domain Receptor (DDR)
T70178	Sonidegib metabolite M25
	Sonidegib metabolite M25 is a smoothened (SMO) antagonist.
T17155	Trabectedin	Ecteinascidin 743,ET-743	Apoptosis , Reactive Oxygen Species
	Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...		Apoptosis , Reactive Oxygen Species
T67325	6,7-Dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
	6,7-Dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67325 and the CAS number is 204827...
T66594	2-(tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
	2-(tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66594 and the CAS number is 851784-82-2.
TN1519	(S)-Coclaurine	Coclaurine	AChR
	(S)-Coclaurine (Coclaurine) is an antagonist of nAChR isolated from Sarcopetalum harveyanum.		AChR
T0111	Solifenacin succinate	YM905	AChR
	Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.		AChR
T78556	Antidepressant agent 5		Others
	Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine in the study of depression and can be used for the prevention...		Others
T27436	GS 389	GS-389,GS389
	GS 389 is a novel tetrahydroisoquinoline analog with vasorelaxant properties. GS-389 significantly inhibited cGMP phosphodiesterase from the rabbit brain and increased cGMP levels in the rat aorta.
T11150	Ecteinascidin 770	Ecteinascidine 770,Et-770	Others
	Ecteinascidin 770 (ET-770) inhibits U373MG cells and is a 1,2,3, 4-tetrahydroisoquinoline alkaloid with strong anticancer activity.IC50 is 4.83 nM.		Others
T11151	Ecteinascidin-Analog-1		Others
	Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues.		Others
T11367	Gastrofensin AN 5 free base		Others
	Gastrofensin AN 5 free base, is an antiulcer agent. a 4-phenyl-tetrahydroisoquinoline derivative.		Others
T74146	Ecubectedin
	Ecubectedin (PM14), a derivative within the ecteinascidins family of tetrahydroisoquinoline alkaloids, exhibits a broad spectrum of antitumor and antimicrobial properties.
T39121	Odatroltide	DHDMIQK(KAP),Odatroltide
	Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus.
T36761	KRAS inhibitor-10
	KRAS inhibitor-10 (WO2021005165 A1, compound 11) is a potent and selective inhibitor of RAS proteins, with a specific focus on KRAS proteins. This orally active anti-cancer agent demonstrates strong efficacy in cancer re...
T72697	Nrf2 activator-6
	Nrf2 Activator-6, a tetrahydroisoquinoline compound, functions as an Nrf2 activator, demonstrating potency with an IC50 value of 5 nM in inhibiting the Kelch domain-Nrf2 interaction.