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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T25748 | L-Nabe | N(w)-nitroarginine benzyl ester,H-Arg(NO2)-Obzl,N-Nitro-L-argininebenzyl ester,NABE,Benzyl Nw-nitro-L-argininate | Others |
L-Nabe (H-Arg(NO2)-Obzl) is a effective irreversible endothelium dependent relaxation inhibitor. | |||
TQ0238 | Lanabecestat | LY3314814,AZD3293 | BACE |
Lanabecestat (AZD3293) is a highly potent and highly permeable, orally active BACE1 inhibitor (Ki: 0.4 nM) that crosses the blood-brain barrier, Lanabecestat can be used for the study of neurological diseases like Alzhei... | |||
T21957 | Guanabenz hydrochloride | NE56490 | Adrenergic Receptor |
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects. | |||
T5471 | GUANABENZ | Adrenergic Receptor | |
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist. | |||
T6522 | Guanabenz Acetate | Wy8678 acetate,BR-750,Wytensin | Adrenergic Receptor |
Guanabenz Acetate (Wytensin) is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25, 7.01 and ~5, respectively. | |||
T38146 | Chloroguanabenz (acetate) | ||
Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz . It inhibits prion formation in yeast and mammalian cell-based assays. Chloroguanabenz reduces the levels of both so... | |||
T10014 | (1α,1'S,4β)-Lanabecestat | (1α,1'S,4β)-AZD3293 | Others |
(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively. | |||
T70807 | Lanabecestat HCl | ||
Lanabecestat, also known as AZD3293 and LY3314814, is a potent, highly permeable, orally active, blood-brain barrier (BBB) penetrating, BACE1 inhibitor with unique slow off-rate kinetics. AZD3293 displayed significant do... | |||
T60304 | (E)-Guanabenz | ||
(E)-Guanabenz ((E)-Wy-8678), an oral central α2-adrenoceptor agonist, exhibits antihypertensive and neuroprotective activities by stimulating central α2-adrenoceptors to reduce sympathetic outflow and directly inhibiting... | |||
TN4833 | Prostephanaberrine | Others | |
Prostephanaberrine is a natural product from Stephania japonica. | |||
T17116 | Tonabersat | SB-220453 | Others |
Tonabersat is a modulator of the gap-junction. | |||
TQ0149 | Prinaberel | ERB 041 | Estrogen/progestogen Receptor |
Prinaberel (ERB-041) is an effective and selective ERβ agonist and >200-fold selective for ERβ. | |||
T25610 | Lanabecestat camsylate | LY 3314814 camsylate,LY-3314814 camsylate,LY3314814 camsylate | |
Lanabecestat camsylate is used as a BACE1 Inhibitor. |