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Cat No. | Product Name | Synonyms | Targets |
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T21798L | Dynamin inhibitory peptide Acetate | Dynamin inhibitory peptide Acetate(251634-21-6 Free base) | GTPase |
Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin. | |||
T64369 | Dynamin IN-2 | Dynamin | |
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM). | |||
TP1907L1 | Dynamin inhibitory peptide, myristoylated acetate | Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base) | Dynamin |
Dynamin inhibitory peptide, myristoylated acetate is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, myristoylated TFA is a membrane-permeant form of the peptide... | |||
T1848 | Dynasore | Dynamin Inhibitor I | Dynamin , Virus Protease , Autophagy , HSV |
Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also inhibits the mitochondrial dynamin Drp1, ... | |||
TP1907 | DynaMin inhibitory peptide, myristoylated | ||
Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. | |||
TP2039 | Dynamin inhibitory peptide, myristoylated (control) | ||
Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibit... | |||
T72952 | Dynamin IN-1 | ||
Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM . | |||
T75796 | Dynamin inhibitory peptide TFA | ||
Dynamin inhibitory peptide TFA competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide TFA blocks the dopamine D 3 effect on GABA A receptors [1] . | |||
T6822 | Hydroxy-Dynasore | Dyngo-4a | Dynamin |
Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively. | |||
T1907 | Mdivi-1 | Mitochondrial division inhibitor 1 | Apoptosis , Mitophagy , Dynamin , Autophagy |
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondrial autophagy. | |||
T22445 | Trimethyloctadecylammonium bromide | Dynamin | |
Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ. | |||
T30479 | Bis-T-23 | Bis T-23,Bis-T 23,AG1717 | HIV Protease |
Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative. Bis-T-23 promotes actin-dependent dynamin oligomerization. Bis-T-23 can be used in studies of HIV... | |||
TP1947L | P110 TFA | Others | |
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. | |||
T22981 | Tetradecyltrimethylammonium bromide | MitMAB,Cetrimide,tetradecyl trimethyl ammonium bromide | Dynamin |
Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure. | |||
T35548 | Dynapyrazole A | Dynamin | |
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM. | |||
T77772 | MiTMAB | ||
MiTMAB, a selective dynamin inhibitor, targets the interaction between dynamin and phospholipids. This inhibitor can inhibit dynamin GTPase activity with a Ki value of 940 nM. | |||
T38407 | RTIL 13 | ||
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound e... | |||
T22754 | Dynole 34-2 | Others | |
Dynamin I inhibitor | |||
T37023 | MB 0223 | ||
Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fu... | |||
T83891 | Sulfonadyn-47 | ||
Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 µM in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 µM) an... | |||
TP1947 | P110 | ||
Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen... | |||
T61488 | Dynole 2-24 | ||
Dynole 2 24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 μM for dynamin I). Dynole 2 24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC (CME) =1.9 μM). Dynole 2 2... | |||
T68788 | Ellipticine quinone | ||
Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency tha... | |||
T73456 | DRP1i27 | ||
DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line... |
Cat No. | Product Name | Synonyms | Targets |
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T3898 | Schaftoside | APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside | Dynamin , Antioxidant , TLR , MyD88 , Mitochondrial Metabolism , Autophagy |
Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03439 | UBASH3A Protein, Human, Recombinant (aa 354-623, His) | Human | E. coli |
UBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apopto... | |||
TMPH-02835 | PDGFD Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry. This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, includi... | |||
TMPH-01621 | BRCC3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through... |