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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TWS1977 | Kamebakaurin | Kamebakaurine | NF-κB |
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression... | |||
T6995 | Ochromycinone | STA 21,STA21,STA-21 | Antibacterial , STAT |
Ochromycinone (STA 21) is a selective STAT3 inhibitor. | |||
T4050 | GSK2981278 | ROR gama modulator 1 | ROR |
GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma). | |||
T6823 | E3330 | HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis | |
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. | |||
T15486 | HLM006474 | Others | |
HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 µM in A375 cells). | |||
T13592 | Calf thymus DNA | DNA from calf thymus, Thymonucleic acid | DNA/RNA Synthesis |
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, which can be widely used in the study of DNA binding anticancer agents and ... | |||
T12019 | Methylproamine | Others | |
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA. | |||
T64372 | DB722 | Others | |
DB722 is a furamidine analogues with DNA binding activity. DB722 shows antiproliferative activity. | |||
T60051 | VPC-18005 | Others | |
VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA. | |||
T19827 | DAPI Dihydrochloride | FxCycle Violet,4',6-diamidino-2-phenylindole | Others |
DAPI Dihydrochloride (FxCycle Violet) is a cell-permeable fluorescent probe by binding in the minor grove of A-T rich sequences of DNA, used to stain DNA and chromosomes, with a preference for adenine and thymine rich DN... | |||
T7388 | GSK805 | ROR | |
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA bindi... | |||
T18883 | 2-Di-1-ASP | Others | |
2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA. | |||
T8334 | CADD522 | MFCD00167693 | Others |
CADD522 (MFCD00167693) is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity | |||
T10268 | AGX51 | Others | |
AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death. | |||
T9879 | Hydroxystilbamidine | Oxistilbamidinum,(E)-hydroxystilbamidine,2-Hydroxy-4,4'-diguanylstilbene,Bis(8-hydroxyquinolinium) sulphate | Others |
Hydroxystilbamidine ((E)-hydroxystilbamidine), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases. | |||
T11332 | FUBP1-IN-1 | FUBP1–IN-1 | Others |
FUBP1 - in-1, with an IC50 value of 11.0 M, is an effective FUSE binding protein 1 (FUBP1) inhibitor that can interfere with the binding of FUBP1 to its SINGLE-strand target DNA FUSE sequence. | |||
T6228 | Irinotecan | CPT-11,Topotecin,(+)-Irinotecan | Topoisomerase , Autophagy |
Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I). Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting... | |||
T23133 | Pentamidine | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal | |
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. | |||
T27613 | InS3-54-A26 | STAT | |
inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3. | |||
T8858 | DTHIB | HSP | |
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation. |