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Chlorin E6

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Chlorin E6
Ce6, Chlorin e6, CE6
T3646619660-77-6
Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg kg, i.v., 50-200 J cm2 irradiation) resulted in complete tumor disappearance after varying degrees of irradiation. Agents including Chlorin E6 were tested in a Phase I clinical study in patients with early superficial squamous cell carcinoma of bronchial origin with favorable results (40 mg m2, IV, 100 J cm2 laser irradiation). In a Phase II clinical trial in patients with early stage lung cancer, the same mode of administration resulted in a complete response in 82.9% of patients. Chlorin E6 has been investigated as a nanotechnology drug delivery tool.
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7-10 days
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RCK00826
RCK 00826, Monotyrosine amide of chlorin e6 trisodium salt, RCK-00826
TN8384
RCK00826, also known as Monotyrosine amide of chlorin e6 trisodium salt, is a naturally derived porphyrin compound.
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