7 tfa ap 7 deaza ddg

7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1) is a nucleotide derivative used in producing thiotriphosphate nucleotide dye terminators for DNA sequencing reactions.

AkaLumine hydrochloride is a fluorescein analog with a Km value of 2.06 μM for recombinant fluorescent protein.

Thioflavine S (Direct Yellow 7) is a fluorescent histochemical marker.

Pyranine (Solvent Green 7) is reported as a new class of fluorescent chemosensor for the Cu+ ion.

7-Hydroxycoumarin-3-carboxylic acid (7-HC-3-CA) is a safe anti-browning agent that inhibits tyrosinase activity, used in food preservation and human pigmentation research.

2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the degree of overall oxidative stress.

3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) is a macrophage inhibitor of macrophage inhibitory factor (MIF) interconjugate isomerase with a Ki of 2.9 μM. 3-Cyano-7-hydroxycoumarin belongs to the group of coumarin derivatives, which can be used as molecular probes and fluorescent dyes.

Sudan II (Solvent Orange 7) is a dyes.

H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex Em=488 525 nm) with cell membrane permeability.

Sulfidefluor-7 AM (SF7-AM) is an effective and cell permeable fluorescent probe for hydrogen sulfide (h2s). Sulfidefluor-7 AM contains acetoxy-methyl ester, which is hydrolyzed intracellular to capture the probe.

6-Ethyl-7-hydroxy-4-methylchromen-2-one is a fluorescent dye.

CY7-SE Triethylamine is a fluorescence labeling agent (Ex=700-770 nm,Em=790 nm) used for labeling proteins, peptides, antibodies, and oligonucleotides.

3-Cyano-7-ethoxycoumarin is cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2 .

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65277 and the CAS number is 6950-82-9.

7-Dimethylaminocoumarin-4-acetic acid, catalog number T64950, CAS number 80883-54-1, is a valuable organic compound for life sciences research.

NBD-X acid, a fluorescent probe for studying fatty acids and sterols, offers higher labeling yields for biopolymers than NBD chloride and fluoride. Its fluorescence spectrum is highly sensitive to environmental changes, with fluorescence intensity significantly decreased in aqueous solutions [1].

7-Diethylamino-3-N-(4-maleimidopropyl)carbamoylcoumarin is a versatile dye utilized across various fields. This compound is primarily important in biological experiments for observing and analyzing cell structures, tracking biomolecules, evaluating cell functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications extend beyond basic scientific research into clinical diagnostics. Additionally, it is employed in traditional industries like textile dyeing and in innovative areas including functional textile processing, food pigments, and dye-sensitized solar cells.

2-(7-Methoxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T64951 and the CAS number is 62935-72-2.

Sulfo-Cy3-Methyltetrazine (figure 7 compound 5), a click chemistry reagent, comprises methyltetrazine linked to a water-soluble dye. This compound demonstrates good stability at physiological pH and can efficiently couple to trans-cyclooctene, showing high reactivity towards cyclooctene [1].

Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation emission maxima of 340-360 and 440-460 nm, respectively.

4-(1-Methylhydrazino)-7-nitrobenzofurazan serves as a versatile dye with applications extending from basic scientific research to clinical diagnostics. Dyes, crucial for various biological experiments, enable scientists to examine cell structures, track biomolecules, assess cell functionality, identify different cell types, detect biomolecules, explore tissue pathology, and observe microorganisms. Beyond scientific research, dyes are prevalent in traditional sectors like textile dyeing and emerging areas, including functional textile processing, food pigments, and dye-sensitized solar cells.

Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 is a fluorogenic substrate designed for the quantification of β-secretase (BACE) activity. When cleaved by BACE, it liberates 7-methoxycoumarin-4-acetyl (Mca), a compound whose fluorescence, with excitation and emission peaks at 328 nm and 420 nm respectively, serves as a measurable indicator of BACE enzymatic action.

L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation emission maxima of 340-360 440-460 nm, respectively. 1.Izquierdo, M., Lin, D., O'Neill, S., et al.Development of a high-throughput screening assay to identify inhibitors of the major M17-leucyl aminopeptidase from Trypanosoma cruzi using rapidfire mass spectrometrySLAS Discov.25(9)1064-1071(2020)

The cell-permeant pH indicator, carboxy SNARF-1, acetoxymethyl ester, acetate (CAS #126208-13-7) has a pKa of ~7.5 after de-esterification, thus is useful for measuring pH changes between pH 7 and pH 8. Carboxy-SNARF-1 exhibits a significant pH-dependent