Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic, antioxidant, hepatoprotective, anti-tumor and anti-inflammatory activities.
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy by inhibiting mTOR signaling.
Alphitolic acid, a terpenoid from Potentilla freyniana Bornm, is a selective 3-hydroxy-3-methylglutamic acid coenzyme-A synthase 2 (HMGCS2) inhibitor with anti-inflammatory and anticancer activity that inhibits T cell proliferation in a concentration-dependent manner. Alphitolic acid induces apoptosis and autophagy.
1. Homogentisic acid (2,5-dihydroxyphenylacetic acid) shows interesting antioxidant and antiradical activities, and protective effect against thermal-cholesterol degradation, comparable to those of well known antioxidants. 2. Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. 3. A derivative of homogentisic acid which inhibits Pfnek-1 with an IC(5) around 1.8 muM, this product is moderately active in vitro against a FcB1 P. falciparum strain (IC(5) = 12 muM).
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and a lead compound for developing novel anti-HIV-1 drugs. It scavenges DPPH free radicals with an IC50 value of 21.8 μM, inhibits aromatase activity with an IC50 value of 6.8 μM, and exhibits cytotoxic activity towards the MOLT-3 cell line with an IC50 value of 3.9 μM.
Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-κB and STAT3 signalling cascades. Myricanone shows in vitro testost
3,4-Secotirucalla-4(28,7,24-triene-3),26-dioic acid is a natural product of Morella, Myricaceae. The catalog number is TN2889 and the CAS number is 159623-48-0. 3,4-Secotirucalla-4(28,7,24-triene-3),26-dioic acid can be used as a reference standard.
Masticadienolic acid is a specific competitive inhibitor of secreted phospholipase A2, it not only protects the active site histidine from alkylation but also inhibits the action of secreted from pancreas, synovial fluid, and bee venom. Masticadienolic ac
Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN4607 and the CAS number is 142449-93-2.