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Dynamin

Dynamin is a GTPase responsible for exocytosis in the eukaryotic cell. Dynamin is part of the "dynamin superfamily", which includes classical dynamins, dynamin-like proteins, Mx proteins, OPA, mitofusins, and GBPs. Members of the dynamin family are principally involved in the scission of newly formed vesicles from the membrane of one cellular compartment and their targeting to, and fusion with, another compartment, both at the cell surface (particularly caveolae internalization) as well as at the Golgi apparatus. Dynamin family members also play a role in many processes including division of organelles, cytokinesis and microbial pathogen resistance.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T1848 Dynasore 304448-55-3 99.89%
Dynasore
Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-fre...
T22445 Trimethyloctadecylammonium bromide 1120-02-1 99.85%
Trimethyloctadecylammonium bromide
Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.
TP1907L1 Dynamin inhibitory peptide, myristoylated acetate TP1907L1 99.42%
Dynamin inhibitory peptide, myristoylated acetate
Dynamin inhibitory peptide, myristoylated acetate is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, m...
T64369 Dynamin IN-2 1345853-49-7 98.81%
Dynamin IN-2
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin m...
T1907 Mdivi-1 338967-87-6 98.79%
Mdivi-1
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondria...
T35548 Dynapyrazole A 2226517-75-3 98.01%
Dynapyrazole A
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole ...
T6822 Hydroxy-Dynasore 1256493-34-1 98%
Hydroxy-Dynasore
Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respe...
T22981 Tetradecyltrimethylammonium bromide 1119-97-7 100%
Tetradecyltrimethylammonium bromide
Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.
T3898 Schaftoside 51938-32-0 100%
Schaftoside
Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.
Dynasore
T1848
Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-fre...
Trimethyloctadecylammonium bromide
T22445
Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.
Dynamin inhibitory peptide, myristoylated acetate
TP1907L1
Dynamin inhibitory peptide, myristoylated acetate is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, m...
Dynamin IN-2
T64369
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin m...
Mdivi-1
T1907
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondria...
Dynapyrazole A
T35548
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole ...
Hydroxy-Dynasore
T6822
Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respe...
Tetradecyltrimethylammonium bromide
T22981
Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.
Schaftoside
T3898
Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.
TargetMol