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Carboxypeptidase

A carboxypeptidase is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of a protein or peptide. This is in contrast to aminopeptidases, which cleave peptide bonds at the N-terminus of proteins. Humans, animals, bacteria and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation.

  • 2-PMPA
    T3440173039-10-6
    2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).
    • $61
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  • GNE-375
    T274231926989-06-1In house
    GNE-375 is a selective and potent BRD9 inhibitor (IC50: 5 nM).GNE-375 inhibits BRD4, TAF1, and CECR2, and can be used to study epigenetic resistance.
    • $119
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  • CPA inhibitor
    T10876223532-02-3In house
    CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.
    • $52
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  • CeMMEC13
    T68011790895-25-8
    CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
    • $39
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  • Carboxypeptidase G2 (CPG2) Inhibitor
    T10678192203-60-4
    Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.
    • $48
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    TargetMol | Inhibitor Sale
  • 2-Benzylsuccinic acid
    T8093884-33-3
    2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a metabolite produced by bacteria as they process xenobiotic compounds.
    • $48
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  • BAY-299
    T145022080306-23-4
    BAY-299 is an effecitve inhibitor of the bromodomain and PHD finger family member BRPF2 and the TATA box binding protein-associated factors TAF1 and TAF1L with IC50s of 67 nM, 8 nM, and 106 nM, respectively.
    • $43
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    TargetMol | Inhibitor Sale
  • CeMMEC1
    T4345440662-09-9In house
    CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
    • $30
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    TargetMol | Inhibitor Sale
  • Mergetpa
    T7823977102-28-4
    Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].
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