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Cat No. | Product Name | Synonyms | Targets |
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T5489 | Tryptophan, N-indol-3-ylacetyl- (6CI) | N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan | Glucosidase |
Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) is involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses. It may also be used in th... | |||
T9343 | N-Cbz-DL-tryptophan | cholecystokinin | |
N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8. | |||
T7694 | 6-fluoro-DL-Tryptophan | 5-HT Receptor | |
6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis. | |||
TN7093 | N-Caffeoyltryptophan | trans-Caffeoyl-L-tryptophan | Sirtuin |
N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM). | |||
T2038 | RG108 | N-Phthalyl-L-tryptophan | DNA Methyltransferase |
RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM). | |||
T38112 | DL-Tryptophan octyl ester (hydrochloride) | ||
Tryptophan is an amino acid precursor of serotonin and melatonin. DL-Tryptophan octyl ester is a tryptophan derivative with an octyl ester protected COOH group. This addition creates a stable, cell-permeable molecule cap... | |||
T20540 | N-Valyltryptophan | Val-trp,L-Valyl-L-tryptophan | Others |
N-Valyltryptophan (Val-trp) is an incomplete breakdown product of protein catabolism or protein digestion. | |||
T11449L | Golotimod | SCV 07,Gamma-D-glutamyl-L-tryptophan | STAT |
Golotimod is an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. | |||
T33801 | O-Nitrophenylsulfenyl-lysyl-tryptophan | ||
o-Nitrophenylsulfenyl-lysyl-tryptophan is a bioactive chemical. | |||
T6543 | Indoximod | NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan | Indoleamine 2,3-Dioxygenase (IDO) |
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan... | |||
T125055 | N-Malonyl DL-tryptophan | ||
N-Malonyl DL-tryptophan is a useful organic compound for research related to life sciences and the catalog number is T125055. | |||
T33323 | Methionyltryptophan | Met-trp,Methionyl-tryptophan,Methionyl tryptophan | |
Methionyl-Tryptophan is a dipeptide composed of methionine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. | |||
T22251 | 680C91 | Others | |
680C91 is a potent and selective inhibitor of TDO, and its Ki is 51 nM. | |||
T21506 | Telotristat | Hydroxylase | |
Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential antiserotonergic activity. | |||
T15796 | LX-1031 | Hydroxylase , LPA Receptor | |
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally. | |||
T4410 | LM10 | Others | |
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters.... | |||
T11449 | Golotimod hydrochloride (229305-39-9 free base) | Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride | STAT |
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts ... | |||
T14119 | ACT-678689 | Compound Example 1.53.4 | Hydroxylase |
ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1]. | |||
T11449L2 | Golotimod (TFA) (229305-39-9 free base) | SCV 07 (TFA),Gamma-D-glutamyl-L-tryptophan (TFA),Golotimod (TFA) | STAT |
Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and impr... | |||
T10142L | P-Ethynylphenylalanine hydrochloride | 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base) | Hydroxylase |
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b... | |||
T11897 | Telotristat ethyl | LX1606 | Hydroxylase |
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production. | |||
T19889 | L-5-BromoTryptophan | 5-BrW,5 BrW | Others |
L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S. | |||
T3119 | JNJ-63533054 | JNJ 63533054 | GPR |
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. | |||
T6044 | Telotristat Etiprate | LX1606 (Hippurate),LX 1606 Hippurate | Hydroxylase |
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. | |||
T1447 | Fenclonine | Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine | Hydroxylase |
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to dep... | |||
T41143 | PCPA methyl ester hydrochloride | 4-Chloro-DL-phenylalanine methyl ester hydrochloride | 5-HT Receptor , Hydroxylase |
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood... | |||
TP2359 | FMOC-DL-7-AZATRYPTOPHAN | 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid | Others |
FMOC-DL-7-AZATRYPTOPHAN (2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid) is a peptide | |||
T76136 | Tryptophanase | ||
Tryptophanase, a bacterial enzyme, catalyzes the degradation of tryptophan into indole, pyruvate, and ammonia [1]. | |||
T20542 | Chloroacetyltryptophan | ||
Chloroacetyltryptophan is a bioactive chemical substance. | |||
T26297 | Tryptophanamide | S-Tryptophanamide | |
Tryptophanamide is a chymotrypsin inhibitor. | |||
T29466 | 5-Oxoprolyltryptophan | 5-O-Pro-trp | |
5-Oxoprolyltryptophan is a bioactive chemical. | |||
T125105 | N-Malonyltryptophan | ||
N-Malonyltryptophan is a useful organic compound for research related to life sciences. The catalog number is T125105 and the CAS number is 29399-11-9. | |||
T31798 | Flavinyltryptophan | ||
Flavinyltryptophan is a flavinyl peptide. | |||
T79189 | 1-Isopropyltryptophan | 1-IsoPT | Indoleamine 2,3-Dioxygenase (IDO) |
1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1]. | |||
T81910 | L-Tryptophanylglycine | ||
L-Tryptophanylglycine (Trp-gly), a dipeptide, inhibits Ceronapril uptake in Caco-2 cells with an inhibition constant (K i) of 7.19 mM [1]. | |||
TP1319 | Indolicidin | Antibacterial | |
Indolicidin is comprised of 13 amino acids, 5 of which are tryptophan residues, and the carboxylterminal arginine is carboxamidated. Indolicidin has the highest tryptophan content of any known protein. | |||
T15779 | LP-533401 hydrochloride | Hydroxylase | |
LP-533401 hydrochloride is an inhibitor of tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut. | |||
T29842 | Alclofenac | W 7320,MY 101,BRN 2116510,W-7320,W7320 | Others |
Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism. | |||
T37683 | 3-Hydroxykynurenine | 3-hydroxy-DL-Kynurenine,DL-3-Hydroxykynurenine | Others |
3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%. | |||
T10142 | P-Ethynylphenylalanine | 4-Ethynyl-L-phenylalanine | Others , Hydroxylase |
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM. | |||
T61202 | TDO-IN-1 | Others | |
TDO-IN-1 is an orally active, potent, and selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which inhibits indoleamine-2,3-dioxygenase.TDO-IN-1 has antitumor activity and is able to act by reversing local immune t... | |||
T19888 | 6BrW | 6-BrW,6 BrW | |
6BrW is an analog of tryptophan effector. | |||
T26258 | Telotristat besilate | ||
Telotristat besilate is an inhibitor of tryptophan hydroxylase. | |||
T16780 | Rodatristat | KAR5417 | Others |
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively). | |||
T15426 | GSK180 | Hydroxylase | |
GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism. | |||
T69135 | AGN-2979 | ||
AGN-2979 is a tryptophan hydroxylase (TPH) activation inhibitor that shows antidepressant properties in rodent models of depression. | |||
T71888 | Fenclonine hydrochloride | ||
Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin. | |||
T11623 | IDO/TDO-IN-1 | Others | |
IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM). | |||
T69944 | NLG802 HCl | ||
NLG802 is an orally bioavailable prodrug of indoximod, a methylated tryptophan, with immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, the indoximod prodrug NLG802 is converted to indo... | |||
T34962 | Tryptophyl-leucyl-glutamic acid | Trp-leu-glu | |
Tryptophyl-leucyl-glutamic acid is a tryptophan used for fluorescence spectroscopy. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2285 | DL-Tryptophan | (±)-Tryptophan,Tryptophan | Serotonin Transporter , Endogenous Metabolite |
DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Lo... | |||
T0439 | L-Tryptophan | (S)-Tryptophan,Tryptophan,L-Tryptophane,Tryptophane | Amino Acids and Derivatives , Endogenous Metabolite |
L-Tryptophan (Tryptophane), an essential amino acid, is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid) and of ... | |||
T5235 | 5-Methoxy-DL-tryptophan | Others , Endogenous Metabolite | |
5-Methoxy-DL-tryptophan is a molecule produced by endothelial cells to modulate inflammatory responses and protect against systemic inflammation. | |||
T8789 | N-Acetyl-L-tryptophan | N-acetyltryptophan | Endogenous Metabolite , Neurokinin receptor |
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R). | |||
T4806 | H-D-Trp-OH | D-Tryptophan | Others , Endogenous Metabolite |
H-D-Trp-OH (D-Tryptophan) is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the marine venom peptide). | |||
T5S0273 | Hypaphorine | Lenticin,Glyyunnanenine,Tryptophan Betaine | Others |
1. Hypaphorine (Lenticin) is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases. | |||
T4833 | Ac-DL-Trp-OH | N-Acetyl-DL-tryptophan | Others , Endogenous Metabolite |
Ac-DL-Trp-OH (N-Acetyl-DL-tryptophan) was study for its possible anti- inflammatory and antinociceptive activities from the extraction of a Turkish plant, Salsola grandis. | |||
T5718 | L-(+)-Abrine | L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE | Others |
L-(+)-Abrine (L-N-Methyltryptophan) is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure. | |||
T3S1967 | (S)-Indoximod | N-ME-Tryptophan,Abrine,L-Abrine | Others , Indoleamine 2,3-Dioxygenase (IDO) |
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L... | |||
T7203 | Oglufanide | L-Glutamyl-L-tryptophan,H-Glu-Trp-OH | VEGFR , HCV Protease , Endogenous Metabolite |
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF). | |||
T3003 | 5-hydroxytryptophan | NSC-92523 | Others , Endogenous Metabolite |
5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. | |||
T1379 | L-5-Hydroxytryptophan | L-oxitriptan,Oxitriptan,L-5-HTP | Amino Acids and Derivatives , Endogenous Metabolite |
L-5-Hydroxytryptophan (L-5-HTP) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. | |||
T5262 | Trans-3-Indoleacrylic acid | trans-IAA | Others , Endogenous Metabolite |
trans-3-Indoleacrylic acid (trans-IAA) is a Tryptophan metabolite. | |||
TQ0265 | Indolelactic acid | Endogenous Metabolite | |
Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures. | |||
T5984 | Indole-3-carboxylic acid | 3-Indoleformic acid | Endogenous Metabolite |
Indole-3-carboxylic acid (3-Indoleformic acid) is a normal urinary indolic tryptophan metabolite . | |||
T20585 | 3-Acetylindole | Acetyl-3-indole,3-Acetyl-1H-indole,3-Acetylindole | Others |
3-Acetylindole (3-Acetyl-1H-indole) can be used as a substituent and a probe to L-tryptophan for Sudlow site II. | |||
T4096 | Quinolinic acid | pyridine-2,3-dicarboxylic acid,QUIN | Endogenous Metabolite , NMDAR , iGluR |
Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway. | |||
T4794 | Glutaric acid | Endogenous Metabolite | |
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan | |||
T7641 | 5-Hydroxytryptophol | Endogenous Metabolite | |
5-Hydroxytryptophol is a metabolite of tryptophan. It is used as a biomarker for recent alcohol consumption and causes sleeping sickness | |||
T4921 | Oxoadipic acid | 2-Oxoadipic acid | Endogenous Metabolite |
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab... | |||
TJO2729 | L-Alanine | L-2-Aminopropionic acid,alanine | Others , Endogenous Metabolite |
L-Alanine (L-2-Aminopropionic acid) is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans, Alanine is one of the most widely used for protein const... | |||
T67710 | 3-Indoleacrylic acid | Endogenous Metabolite | |
3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by im... | |||
T3010 | Xanthurenic Acid | 8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate | Apoptosis , Endogenous Metabolite , GluR |
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3). | |||
T65135 | Kynurenic acid | Fibrostop 2,Quinurenic acid | GPR , GluR , NMDAR |
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv... | |||
T10938 | D-Kynurenine | (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 | GPR , AhR , Endogenous Metabolite |
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor... | |||
T4928 | L-Kynurenine | (S)-Kynurenine | AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite |
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ... | |||
T0647 | Tryptamine | Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r... | |||
T4799 | Indole | Others , Endogenous Metabolite | |
Indole has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a degradation product of the amino acid tryptophan. ... | |||
T4938 | Potassium 1H-indol-3-yl sulfate | Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate | AhR , Endogenous Metabolite |
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm... | |||
T4707 | 3-Hydroxyanthranilic acid | 3-HYDROXY-2-AMINOBENZOIC ACID | Others , Endogenous Metabolite |
3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthranilic acid... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01959 | Tryptophan Hydroxylase 1/TPH-1 Protein, Human, Recombinant (His) | Human | E. coli |
Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 cont... | |||
TMPJ-00819 | Trp A Protein, E. coli, Recombinant | E.coli | E. coli |
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as ... | |||
TMPJ-00820 | Trp B Protein, E. coli, Recombinant (His) | E.coli | E. coli |
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as ... | |||
TMPH-02958 | Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. | |||
TMPY-02584 | 14-3-3 beta Protein, Cynomolgus, Recombinant | Cynomolgus | E. coli |
14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t... | |||
TMPY-02179 | 14-3-3 epsilon Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co... | |||
TMPY-02378 | 14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST) | Human | E. coli |
The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp... | |||
TMPY-02377 | 14-3-3 eta/YWHAH Protein, Human, Recombinant (GST) | Human | E. coli |
YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on ... | |||
TMPY-01267 | 14-3-3 epsilon Protein, Human, Recombinant (GST) | Human | E. coli |
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co... | |||
TMPY-01266 | 14-3-3 beta Protein, Human, Recombinant (GST) | Human | E. coli |
14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t... | |||
TMPY-01273 | 14-3-3 beta Protein, Human, Recombinant | Human | E. coli |
14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t... | |||
TMPY-01274 | 14-3-3 epsilon Protein, Human, Recombinant | Human | E. coli |
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-06772 | IDO Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Indoleamine 2,3-dioxygenase-1, also known as Indoleamine-pyrrole 2,3-dioxygenase, IDO1, and IDO, is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degra... | |||
TMPY-02928 | IDO Protein, Human, Recombinant | Human | E. coli |
Indoleamine 2,3-dioxygenase-1, also known as Indoleamine-pyrrole 2,3-dioxygenase, IDO1, and IDO, is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degra... | |||
TMPH-01598 | CCBL2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre... | |||
TMPH-01597 | KYAT1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre... | |||
TMPY-01821 | IDO Protein, Human, Recombinant (His) | Human | E. coli |
Indoleamine 2,3-dioxygenase-1, also known as Indoleamine-pyrrole 2,3-dioxygenase, IDO1, and IDO, is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degra... | |||
TMPH-02679 | QPCT Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue... | |||
TMPH-02680 | QPCT Protein, Mouse, Recombinant (His & Myc) | Mouse | HEK293 |
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue... | |||
TMPH-00726 | Ribokinase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a compone... | |||
TMPY-02803 | IDO2 Protein, Human, Recombinant (His) | Human | E. coli |
IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of trypt... | |||
TMPH-01596 | AADAT Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a vari... | |||
TMPJ-01110 | IRF5 Protein, Human, Recombinant (His) | Human | E. coli |
Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it ... | |||
TMPY-00726 | Carboxypeptidase A2 Protein, Human, Recombinant (His) | Human | HEK293 |
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was id... | |||
TMPY-02664 | Carboxypeptidase A2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was id... | |||
TMPJ-00813 | QDPR Protein, Human, Recombinant (His) | Human | Human Cells |
Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pa... | |||
TMPJ-01197 | CRELD2 Protein, Human, Recombinant (His) | Human | Human Cells |
Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserve... | |||
TMPJ-00473 | QPRTase Protein, Human, Recombinant (His) | Human | E. coli |
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ... | |||
TMPY-00332 | CPA2 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was id... | |||
TMPY-03753 | WARS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochon... | |||
TMPY-06815 | SYAP1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the ... | |||
TMPJ-00602 | CPA2 Protein, Human, Recombinant (His) | Human | Human Cells |
Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified... | |||
TMPH-01604 | SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptop... | |||
TMPY-06611 | CD98 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-04631 | CD98 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-03307 | CD98 Protein, Rat, Recombinant (His) | Rat | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPH-01248 | ADAR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPH-01249 | ADAR Protein, Human, Recombinant (GST) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... |
Cat No. | Product Name | ||
---|---|---|---|
L2800 | Serotonin Receptor-Targeted Compound Library | 275 compounds | |
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening; |