Home Tools
Log in
Cart

Search Result

Search Results for " tryptophan "

Targets

80

Compounds

30

Natural Products

40

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T5489 Tryptophan, N-indol-3-ylacetyl- (6CI) N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan Glucosidase
Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) is involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses. It may also be used in th...
T9343 N-Cbz-DL-tryptophan cholecystokinin
N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8.
T7694 6-fluoro-DL-Tryptophan 5-HT Receptor
6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis.
TN7093 N-Caffeoyltryptophan trans-Caffeoyl-L-tryptophan Sirtuin
N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
T2038 RG108 N-Phthalyl-L-tryptophan DNA Methyltransferase
RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).
T38112 DL-Tryptophan octyl ester (hydrochloride)
Tryptophan is an amino acid precursor of serotonin and melatonin. DL-Tryptophan octyl ester is a tryptophan derivative with an octyl ester protected COOH group. This addition creates a stable, cell-permeable molecule cap...
T20540 N-Valyltryptophan Val-trp,L-Valyl-L-tryptophan Others
N-Valyltryptophan (Val-trp) is an incomplete breakdown product of protein catabolism or protein digestion.
T11449L Golotimod SCV 07,Gamma-D-glutamyl-L-tryptophan STAT
Golotimod is an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function.
T33801 O-Nitrophenylsulfenyl-lysyl-tryptophan
o-Nitrophenylsulfenyl-lysyl-tryptophan is a bioactive chemical.
T6543 Indoximod NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan Indoleamine 2,3-Dioxygenase (IDO)
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan...
T125055 N-Malonyl DL-tryptophan
N-Malonyl DL-tryptophan is a useful organic compound for research related to life sciences and the catalog number is T125055.
T33323 Methionyltryptophan Met-trp,Methionyl-tryptophan,Methionyl tryptophan
Methionyl-Tryptophan is a dipeptide composed of methionine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism.
T22251 680C91 Others
680C91 is a potent and selective inhibitor of TDO, and its Ki is 51 nM.
T21506 Telotristat Hydroxylase
Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential antiserotonergic activity.
T15796 LX-1031 Hydroxylase , LPA Receptor
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.
T4410 LM10 Others
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters....
T11449 Golotimod hydrochloride (229305-39-9 free base) Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride STAT
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts ...
T14119 ACT-678689 Compound Example 1.53.4 Hydroxylase
ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].
T11449L2 Golotimod (TFA) (229305-39-9 free base) SCV 07 (TFA),Gamma-D-glutamyl-L-tryptophan (TFA),Golotimod (TFA) STAT
Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and impr...
T10142L P-Ethynylphenylalanine hydrochloride 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base) Hydroxylase
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b...
T11897 Telotristat ethyl LX1606 Hydroxylase
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
T19889 L-5-BromoTryptophan 5-BrW,5 BrW Others
L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S.
T3119 JNJ-63533054 JNJ 63533054 GPR
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
T6044 Telotristat Etiprate LX1606 (Hippurate),LX 1606 Hippurate Hydroxylase
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
T1447 Fenclonine Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine Hydroxylase
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to dep...
T41143 PCPA methyl ester hydrochloride 4-Chloro-DL-phenylalanine methyl ester hydrochloride 5-HT Receptor , Hydroxylase
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood...
TP2359 FMOC-DL-7-AZATRYPTOPHAN 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid Others
FMOC-DL-7-AZATRYPTOPHAN (2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid) is a peptide
T76136 Tryptophanase
Tryptophanase, a bacterial enzyme, catalyzes the degradation of tryptophan into indole, pyruvate, and ammonia [1].
T20542 Chloroacetyltryptophan
Chloroacetyltryptophan is a bioactive chemical substance.
T26297 Tryptophanamide S-Tryptophanamide
Tryptophanamide is a chymotrypsin inhibitor.
T29466 5-Oxoprolyltryptophan 5-O-Pro-trp
5-Oxoprolyltryptophan is a bioactive chemical.
T125105 N-Malonyltryptophan
N-Malonyltryptophan is a useful organic compound for research related to life sciences. The catalog number is T125105 and the CAS number is 29399-11-9.
T31798 Flavinyltryptophan
Flavinyltryptophan is a flavinyl peptide.
T79189 1-Isopropyltryptophan 1-IsoPT Indoleamine 2,3-Dioxygenase (IDO)
1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].
T81910 L-Tryptophanylglycine
L-Tryptophanylglycine (Trp-gly), a dipeptide, inhibits Ceronapril uptake in Caco-2 cells with an inhibition constant (K i) of 7.19 mM [1].
TP1319 Indolicidin Antibacterial
Indolicidin is comprised of 13 amino acids, 5 of which are tryptophan residues, and the carboxylterminal arginine is carboxamidated. Indolicidin has the highest tryptophan content of any known protein.
T15779 LP-533401 hydrochloride Hydroxylase
LP-533401 hydrochloride is an inhibitor of tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.
T29842 Alclofenac W 7320,MY 101,BRN 2116510,W-7320,W7320 Others
Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.
T37683 3-Hydroxykynurenine 3-hydroxy-DL-Kynurenine,DL-3-Hydroxykynurenine Others
3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%.
T10142 P-Ethynylphenylalanine 4-Ethynyl-L-phenylalanine Others , Hydroxylase
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM.
T61202 TDO-IN-1 Others
TDO-IN-1 is an orally active, potent, and selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which inhibits indoleamine-2,3-dioxygenase.TDO-IN-1 has antitumor activity and is able to act by reversing local immune t...
T19888 6BrW 6-BrW,6 BrW
6BrW is an analog of tryptophan effector.
T26258 Telotristat besilate
Telotristat besilate is an inhibitor of tryptophan hydroxylase.
T16780 Rodatristat KAR5417 Others
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).
T15426 GSK180 Hydroxylase
GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.
T69135 AGN-2979
AGN-2979 is a tryptophan hydroxylase (TPH) activation inhibitor that shows antidepressant properties in rodent models of depression.
T71888 Fenclonine hydrochloride
Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.
T11623 IDO/TDO-IN-1 Others
IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).
T69944 NLG802 HCl
NLG802 is an orally bioavailable prodrug of indoximod, a methylated tryptophan, with immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, the indoximod prodrug NLG802 is converted to indo...
T34962 Tryptophyl-leucyl-glutamic acid Trp-leu-glu
Tryptophyl-leucyl-glutamic acid is a tryptophan used for fluorescence spectroscopy.

Compounds

Tryptophan, N-indol-3-ylacetyl- (6CI)
T5489
Synonym: N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan
Target: Glucosidase
N-Cbz-DL-tryptophan
T9343
Synonym:
Target: cholecystokinin
6-fluoro-DL-Tryptophan
T7694
Synonym:
Target: 5-HT Receptor
N-Caffeoyltryptophan
TN7093
Synonym: trans-Caffeoyl-L-tryptophan
Target: Sirtuin
RG108
T2038
Synonym: N-Phthalyl-L-tryptophan
Target: DNA Methyltransferase
DL-Tryptophan octyl ester (hydrochloride)
T38112
Synonym:
Target:
N-Valyltryptophan
T20540
Synonym: Val-trp,L-Valyl-L-tryptophan
Target: Others
Golotimod
T11449L
Synonym: SCV 07,Gamma-D-glutamyl-L-tryptophan
Target: STAT
o-Nitrophenylsulfenyl-lysyl-tryptophan
T33801
Synonym:
Target:
Indoximod
T6543
Synonym: NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan
Target: Indoleamine 2,3-Dioxygenase (IDO)
N-Malonyl DL-tryptophan
T125055
Synonym:
Target:
Methionyltryptophan
T33323
Synonym: Met-trp,Methionyl-tryptophan,Methionyl tryptophan
Target:
680C91
T22251
Synonym:
Target: Others
Telotristat
T21506
Synonym:
Target: Hydroxylase
LX-1031
T15796
Synonym:
Target: Hydroxylase, LPA Receptor
LM10
T4410
Synonym:
Target: Others
Golotimod hydrochloride (229305-39-9 free base)
T11449
Synonym: Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride
Target: STAT
ACT-678689
T14119
Synonym: Compound Example 1.53.4
Target: Hydroxylase
Golotimod (TFA) (229305-39-9 free base)
T11449L2
Synonym: SCV 07 (TFA),Gamma-D-glutamyl-L-tryptophan (TFA),Golotimod (TFA)
Target: STAT
p-Ethynylphenylalanine hydrochloride
T10142L
Synonym: 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)
Target: Hydroxylase
Telotristat ethyl
T11897
Synonym: LX1606
Target: Hydroxylase
L-5-BromoTryptophan
T19889
Synonym: 5-BrW,5 BrW
Target: Others
JNJ-63533054
T3119
Synonym: JNJ 63533054
Target: GPR
Telotristat Etiprate
T6044
Synonym: LX1606 (Hippurate),LX 1606 Hippurate
Target: Hydroxylase
Fenclonine
T1447
Synonym: Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine
Target: Hydroxylase
pCPA methyl ester hydrochloride
T41143
Synonym: 4-Chloro-DL-phenylalanine methyl ester hydrochloride
Target: 5-HT Receptor, Hydroxylase
FMOC-DL-7-AZATRYPTOPHAN
TP2359
Synonym: 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid
Target: Others
Tryptophanase
T76136
Synonym:
Target:
Chloroacetyltryptophan
T20542
Synonym:
Target:
Tryptophanamide
T26297
Synonym: S-Tryptophanamide
Target:
5-Oxoprolyltryptophan
T29466
Synonym: 5-O-Pro-trp
Target:
N-Malonyltryptophan
T125105
Synonym:
Target:
Flavinyltryptophan
T31798
Synonym:
Target:
1-Isopropyltryptophan
T79189
Synonym: 1-IsoPT
Target: Indoleamine 2,3-Dioxygenase (IDO)
L-Tryptophanylglycine
T81910
Synonym:
Target:
Indolicidin
TP1319
Synonym:
Target: Antibacterial
LP-533401 hydrochloride
T15779
Synonym:
Target: Hydroxylase
Alclofenac
T29842
Synonym: W 7320,MY 101,BRN 2116510,W-7320,W7320
Target: Others
3-Hydroxykynurenine
T37683
Synonym: 3-hydroxy-DL-Kynurenine,DL-3-Hydroxykynurenine
Target: Others
p-Ethynylphenylalanine
T10142
Synonym: 4-Ethynyl-L-phenylalanine
Target: Others, Hydroxylase
TDO-IN-1
T61202
Synonym:
Target: Others
6BrW
T19888
Synonym: 6-BrW,6 BrW
Target:
Telotristat besilate
T26258
Synonym:
Target:
Rodatristat
T16780
Synonym: KAR5417
Target: Others
GSK180
T15426
Synonym:
Target: Hydroxylase
AGN-2979
T69135
Synonym:
Target:
Fenclonine hydrochloride
T71888
Synonym:
Target:
IDO/TDO-IN-1
T11623
Synonym:
Target: Others
NLG802 HCl
T69944
Synonym:
Target:
Tryptophyl-leucyl-glutamic acid
T34962
Synonym: Trp-leu-glu
Target:
1 2
Cat No. Product Name Synonyms Targets
TN2285 DL-Tryptophan (±)-Tryptophan,Tryptophan Serotonin Transporter , Endogenous Metabolite
DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Lo...
T0439 L-Tryptophan (S)-Tryptophan,Tryptophan,L-Tryptophane,Tryptophane Amino Acids and Derivatives , Endogenous Metabolite
L-Tryptophan (Tryptophane), an essential amino acid, is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid) and of ...
T5235 5-Methoxy-DL-tryptophan Others , Endogenous Metabolite
5-Methoxy-DL-tryptophan is a molecule produced by endothelial cells to modulate inflammatory responses and protect against systemic inflammation.
T8789 N-Acetyl-L-tryptophan N-acetyltryptophan Endogenous Metabolite , Neurokinin receptor
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
T4806 H-D-Trp-OH D-Tryptophan Others , Endogenous Metabolite
H-D-Trp-OH (D-Tryptophan) is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the marine venom peptide).
T5S0273 Hypaphorine Lenticin,Glyyunnanenine,Tryptophan Betaine Others
1. Hypaphorine (Lenticin) is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.
T4833 Ac-DL-Trp-OH N-Acetyl-DL-tryptophan Others , Endogenous Metabolite
Ac-DL-Trp-OH (N-Acetyl-DL-tryptophan) was study for its possible anti- inflammatory and antinociceptive activities from the extraction of a Turkish plant, Salsola grandis.
T5718 L-(+)-Abrine L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE Others
L-(+)-Abrine (L-N-Methyltryptophan) is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.
T3S1967 (S)-Indoximod N-ME-Tryptophan,Abrine,L-Abrine Others , Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...
T7203 Oglufanide L-Glutamyl-L-tryptophan,H-Glu-Trp-OH VEGFR , HCV Protease , Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
T3003 5-hydroxytryptophan NSC-92523 Others , Endogenous Metabolite
5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
T1379 L-5-Hydroxytryptophan L-oxitriptan,Oxitriptan,L-5-HTP Amino Acids and Derivatives , Endogenous Metabolite
L-5-Hydroxytryptophan (L-5-HTP) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
T5262 Trans-3-Indoleacrylic acid trans-IAA Others , Endogenous Metabolite
trans-3-Indoleacrylic acid (trans-IAA) is a Tryptophan metabolite.
TQ0265 Indolelactic acid Endogenous Metabolite
Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.
T5984 Indole-3-carboxylic acid 3-Indoleformic acid Endogenous Metabolite
Indole-3-carboxylic acid (3-Indoleformic acid) is a normal urinary indolic tryptophan metabolite .
T20585 3-Acetylindole Acetyl-3-indole,3-Acetyl-1H-indole,3-Acetylindole Others
3-Acetylindole (3-Acetyl-1H-indole) can be used as a substituent and a probe to L-tryptophan for Sudlow site II.
T4096 Quinolinic acid pyridine-2,3-dicarboxylic acid,QUIN Endogenous Metabolite , NMDAR , iGluR
Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
T4794 Glutaric acid Endogenous Metabolite
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan
T7641 5-Hydroxytryptophol Endogenous Metabolite
5-Hydroxytryptophol is a metabolite of tryptophan. It is used as a biomarker for recent alcohol consumption and causes sleeping sickness
T4921 Oxoadipic acid 2-Oxoadipic acid Endogenous Metabolite
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab...
TJO2729 L-Alanine L-2-Aminopropionic acid,alanine Others , Endogenous Metabolite
L-Alanine (L-2-Aminopropionic acid) is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans, Alanine is one of the most widely used for protein const...
T67710 3-Indoleacrylic acid Endogenous Metabolite
3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by im...
T3010 Xanthurenic Acid 8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate Apoptosis , Endogenous Metabolite , GluR
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).
T65135 Kynurenic acid Fibrostop 2,Quinurenic acid GPR , GluR , NMDAR
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv...
T10938 D-Kynurenine (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 GPR , AhR , Endogenous Metabolite
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor...
T4928 L-Kynurenine (S)-Kynurenine AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...
T0647 Tryptamine Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r...
T4799 Indole Others , Endogenous Metabolite
Indole has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a degradation product of the amino acid tryptophan. ...
T4938 Potassium 1H-indol-3-yl sulfate Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate AhR , Endogenous Metabolite
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm...
T4707 3-Hydroxyanthranilic acid 3-HYDROXY-2-AMINOBENZOIC ACID Others , Endogenous Metabolite
3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthranilic acid...

Natural Products

DL-Tryptophan
TN2285
Synonym: (±)-Tryptophan,Tryptophan
Target: Serotonin Transporter, Endogenous Metabolite
L-Tryptophan
T0439
Synonym: (S)-Tryptophan,Tryptophan,L-Tryptophane,Tryptophane
Target: Amino Acids and Derivatives, Endogenous Metabolite
5-Methoxy-DL-tryptophan
T5235
Synonym:
Target: Others, Endogenous Metabolite
N-Acetyl-L-tryptophan
T8789
Synonym: N-acetyltryptophan
Target: Endogenous Metabolite, Neurokinin receptor
H-D-Trp-OH
T4806
Synonym: D-Tryptophan
Target: Others, Endogenous Metabolite
Hypaphorine
T5S0273
Synonym: Lenticin,Glyyunnanenine,Tryptophan Betaine
Target: Others
Ac-DL-Trp-OH
T4833
Synonym: N-Acetyl-DL-tryptophan
Target: Others, Endogenous Metabolite
L-(+)-Abrine
T5718
Synonym: L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE
Target: Others
(S)-Indoximod
T3S1967
Synonym: N-ME-Tryptophan,Abrine,L-Abrine
Target: Others, Indoleamine 2,3-Dioxygenase (IDO)
Oglufanide
T7203
Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH
Target: VEGFR, HCV Protease, Endogenous Metabolite
5-hydroxytryptophan
T3003
Synonym: NSC-92523
Target: Others, Endogenous Metabolite
L-5-Hydroxytryptophan
T1379
Synonym: L-oxitriptan,Oxitriptan,L-5-HTP
Target: Amino Acids and Derivatives, Endogenous Metabolite
trans-3-Indoleacrylic acid
T5262
Synonym: trans-IAA
Target: Others, Endogenous Metabolite
Indolelactic acid
TQ0265
Synonym:
Target: Endogenous Metabolite
Indole-3-carboxylic acid
T5984
Synonym: 3-Indoleformic acid
Target: Endogenous Metabolite
3-Acetylindole
T20585
Synonym: Acetyl-3-indole,3-Acetyl-1H-indole,3-Acetylindole
Target: Others
Quinolinic acid
T4096
Synonym: pyridine-2,3-dicarboxylic acid,QUIN
Target: Endogenous Metabolite, NMDAR, iGluR
Glutaric acid
T4794
Synonym:
Target: Endogenous Metabolite
5-Hydroxytryptophol
T7641
Synonym:
Target: Endogenous Metabolite
Oxoadipic acid
T4921
Synonym: 2-Oxoadipic acid
Target: Endogenous Metabolite
L-Alanine
TJO2729
Synonym: L-2-Aminopropionic acid,alanine
Target: Others, Endogenous Metabolite
3-Indoleacrylic acid
T67710
Synonym:
Target: Endogenous Metabolite
Xanthurenic Acid
T3010
Synonym: 8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate
Target: Apoptosis, Endogenous Metabolite, GluR
Kynurenic acid
T65135
Synonym: Fibrostop 2,Quinurenic acid
Target: GPR, GluR, NMDAR
D-Kynurenine
T10938
Synonym: (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103
Target: GPR, AhR, Endogenous Metabolite
L-Kynurenine
T4928
Synonym: (S)-Kynurenine
Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite
Tryptamine
T0647
Synonym:
Target: Dehydrogenase, 5-HT Receptor, Endogenous Metabolite, TRP/TRPV Channel
Indole
T4799
Synonym:
Target: Others, Endogenous Metabolite
Potassium 1H-indol-3-yl sulfate
T4938
Synonym: Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate
Target: AhR, Endogenous Metabolite
3-Hydroxyanthranilic acid
T4707
Synonym: 3-HYDROXY-2-AMINOBENZOIC ACID
Target: Others, Endogenous Metabolite

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01959 Tryptophan Hydroxylase 1/TPH-1 Protein, Human, Recombinant (His) Human E. coli
Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 cont...
TMPJ-00819 Trp A Protein, E. coli, Recombinant E.coli E. coli
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as ...
TMPJ-00820 Trp B Protein, E. coli, Recombinant (His) E.coli E. coli
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as ...
TMPH-02958 Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
TMPY-02584 14-3-3 beta Protein, Cynomolgus, Recombinant Cynomolgus E. coli
14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t...
TMPY-02179 14-3-3 epsilon Protein, Mouse, Recombinant (GST) Mouse E. coli
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co...
TMPY-02378 14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST) Human E. coli
The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp...
TMPY-02377 14-3-3 eta/YWHAH Protein, Human, Recombinant (GST) Human E. coli
YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on ...
TMPY-01267 14-3-3 epsilon Protein, Human, Recombinant (GST) Human E. coli
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co...
TMPY-01266 14-3-3 beta Protein, Human, Recombinant (GST) Human E. coli
14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t...
TMPY-01273 14-3-3 beta Protein, Human, Recombinant Human E. coli
14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t...
TMPY-01274 14-3-3 epsilon Protein, Human, Recombinant Human E. coli
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co...
TMPY-01938 CD98 Protein, Human, Recombinant (His) Human HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-02358 CD98 Protein, Mouse, Recombinant (His) Mouse HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-06772 IDO Protein, Mouse, Recombinant (His) Mouse E. coli
Indoleamine 2,3-dioxygenase-1, also known as Indoleamine-pyrrole 2,3-dioxygenase, IDO1, and IDO, is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degra...
TMPY-02928 IDO Protein, Human, Recombinant Human E. coli
Indoleamine 2,3-dioxygenase-1, also known as Indoleamine-pyrrole 2,3-dioxygenase, IDO1, and IDO, is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degra...
TMPH-01598 CCBL2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre...
TMPH-01597 KYAT1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre...
TMPY-01821 IDO Protein, Human, Recombinant (His) Human E. coli
Indoleamine 2,3-dioxygenase-1, also known as Indoleamine-pyrrole 2,3-dioxygenase, IDO1, and IDO, is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degra...
TMPH-02679 QPCT Protein, Mouse, Recombinant (His) Mouse Yeast
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue...
TMPH-02680 QPCT Protein, Mouse, Recombinant (His & Myc) Mouse HEK293
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue...
TMPH-00726 Ribokinase Protein, E. coli, Recombinant (His) E. coli E. coli
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a compone...
TMPY-02803 IDO2 Protein, Human, Recombinant (His) Human E. coli
IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of trypt...
TMPH-01596 AADAT Protein, Human, Recombinant (His & SUMO) Human E. coli
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a vari...
TMPJ-01110 IRF5 Protein, Human, Recombinant (His) Human E. coli
Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it ...
TMPY-00726 Carboxypeptidase A2 Protein, Human, Recombinant (His) Human HEK293
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was id...
TMPY-02664 Carboxypeptidase A2 Protein, Mouse, Recombinant (His) Mouse HEK293
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was id...
TMPJ-00813 QDPR Protein, Human, Recombinant (His) Human Human Cells
Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pa...
TMPJ-01197 CRELD2 Protein, Human, Recombinant (His) Human Human Cells
Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserve...
TMPJ-00473 QPRTase Protein, Human, Recombinant (His) Human E. coli
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ...
TMPY-00332 CPA2 Protein, Rat, Recombinant (His) Rat HEK293
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was id...
TMPY-03753 WARS Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochon...
TMPY-06815 SYAP1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the ...
TMPJ-00602 CPA2 Protein, Human, Recombinant (His) Human Human Cells
Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified...
TMPH-01604 SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptop...
TMPY-06611 CD98 Protein, Human, Recombinant (His), Biotinylated Human HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-04631 CD98 Protein, Rat, Recombinant (hFc) Rat HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-03307 CD98 Protein, Rat, Recombinant (His) Rat HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPH-01248 ADAR Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01249 ADAR Protein, Human, Recombinant (GST) Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
Tryptophan Hydroxylase 1/TPH-1 Protein, Human, Recombinant (His)
TMPY-01959
Species: Human
Expression System: E. coli
Trp A Protein, E. coli, Recombinant
TMPJ-00819
Species: E.coli
Expression System: E. coli
Trp B Protein, E. coli, Recombinant (His)
TMPJ-00820
Species: E.coli
Expression System: E. coli
Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02958
Species: Mouse
Expression System: E. coli
14-3-3 beta Protein, Cynomolgus, Recombinant
TMPY-02584
Species: Cynomolgus
Expression System: E. coli
14-3-3 epsilon Protein, Mouse, Recombinant (GST)
TMPY-02179
Species: Mouse
Expression System: E. coli
14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)
TMPY-02378
Species: Human
Expression System: E. coli
14-3-3 eta/YWHAH Protein, Human, Recombinant (GST)
TMPY-02377
Species: Human
Expression System: E. coli
14-3-3 epsilon Protein, Human, Recombinant (GST)
TMPY-01267
Species: Human
Expression System: E. coli
14-3-3 beta Protein, Human, Recombinant (GST)
TMPY-01266
Species: Human
Expression System: E. coli
14-3-3 beta Protein, Human, Recombinant
TMPY-01273
Species: Human
Expression System: E. coli
14-3-3 epsilon Protein, Human, Recombinant
TMPY-01274
Species: Human
Expression System: E. coli
CD98 Protein, Human, Recombinant (His)
TMPY-01938
Species: Human
Expression System: HEK293
CD98 Protein, Mouse, Recombinant (His)
TMPY-02358
Species: Mouse
Expression System: HEK293
IDO Protein, Mouse, Recombinant (His)
TMPY-06772
Species: Mouse
Expression System: E. coli
IDO Protein, Human, Recombinant
TMPY-02928
Species: Human
Expression System: E. coli
CCBL2 Protein, Human, Recombinant (His & SUMO)
TMPH-01598
Species: Human
Expression System: E. coli
KYAT1 Protein, Human, Recombinant (His & SUMO)
TMPH-01597
Species: Human
Expression System: E. coli
IDO Protein, Human, Recombinant (His)
TMPY-01821
Species: Human
Expression System: E. coli
QPCT Protein, Mouse, Recombinant (His)
TMPH-02679
Species: Mouse
Expression System: Yeast
QPCT Protein, Mouse, Recombinant (His & Myc)
TMPH-02680
Species: Mouse
Expression System: HEK293
Ribokinase Protein, E. coli, Recombinant (His)
TMPH-00726
Species: E. coli
Expression System: E. coli
IDO2 Protein, Human, Recombinant (His)
TMPY-02803
Species: Human
Expression System: E. coli
AADAT Protein, Human, Recombinant (His & SUMO)
TMPH-01596
Species: Human
Expression System: E. coli
IRF5 Protein, Human, Recombinant (His)
TMPJ-01110
Species: Human
Expression System: E. coli
Carboxypeptidase A2 Protein, Human, Recombinant (His)
TMPY-00726
Species: Human
Expression System: HEK293
Carboxypeptidase A2 Protein, Mouse, Recombinant (His)
TMPY-02664
Species: Mouse
Expression System: HEK293
QDPR Protein, Human, Recombinant (His)
TMPJ-00813
Species: Human
Expression System: Human Cells
CRELD2 Protein, Human, Recombinant (His)
TMPJ-01197
Species: Human
Expression System: Human Cells
QPRTase Protein, Human, Recombinant (His)
TMPJ-00473
Species: Human
Expression System: E. coli
CPA2 Protein, Rat, Recombinant (His)
TMPY-00332
Species: Rat
Expression System: HEK293
WARS Protein, Human, Recombinant (His)
TMPY-03753
Species: Human
Expression System: Baculovirus-Insect Cells
SYAP1 Protein, Human, Recombinant (His)
TMPY-06815
Species: Human
Expression System: Baculovirus-Insect Cells
CPA2 Protein, Human, Recombinant (His)
TMPJ-00602
Species: Human
Expression System: Human Cells
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)
TMPH-01604
Species: Human
Expression System: E. coli
CD98 Protein, Human, Recombinant (His), Biotinylated
TMPY-06611
Species: Human
Expression System: HEK293
CD98 Protein, Rat, Recombinant (hFc)
TMPY-04631
Species: Rat
Expression System: HEK293
CD98 Protein, Rat, Recombinant (His)
TMPY-03307
Species: Rat
Expression System: HEK293
ADAR Protein, Human, Recombinant (His & SUMO)
TMPH-01248
Species: Human
Expression System: E. coli
ADAR Protein, Human, Recombinant (GST)
TMPH-01249
Species: Human
Expression System: E. coli
Cat No. Product Name
L2800 Serotonin Receptor-Targeted Compound Library

275 compounds
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening;
TargetMol