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Results for "target/Ras/1" in TargetMol Product Catalog
  • Inhibitor Products
    3
    TargetMol | Activity
  • Recombinant Protein
    1
    TargetMol | inventory
(2Z,3Z)-U0126
T69826218601-62-8
(2Z,3Z)-U0126 is a highly selective inhibitor of both MEK1 and MEK2, a type of MAPK/ERK kinase. It was found to functionally antagonize AP-1 transcriptional activity via noncompetitive inhibition of the dual specificity kinase MEK with IC50 of 72 nM for MEK1 and 58 nM for MEK2. U0126 inhibited anchorage-independent growth of Ki-ras-transformed rat fibroblasts by simultaneously blocking both extracellular signal-regulated kinase and mammalian target of rapamycin pathways.
  • $1,520
6-8 weeks
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QTY
U0126-EtOH
T62231173097-76-1
U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).
  • $30
In Stock
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TargetMol | Citations Cited
U0126
T21332109511-58-2
U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively. U0126 inhibits autophagy and mitophagy.
  • $110
35 days
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TargetMol | Citations Cited