t 4

T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.

T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA. It is utilized for the synthesis of enzymatic oligoribonucleotides and the 3′-terminal labeling of RNA [1] [2].

T4 UvsX Recombinase initiates DNA replication on double-stranded templates by catalyzing synapsis with a homologous primer single strand. It significantly enhances the snap-back (hairpin-primed) DNA synthesis catalyzed by the T4 DNA polymerase holoenzyme on linear, single-stranded templates [1].

T4 UvsY Protein is an accessory protein that catalyzes strand exchange in vitro. It enhances the strand exchange activity of the UvsX protein through specific interactions. Additionally, T4 UvsY Protein increases the rate of single-stranded DNA-dependent ATP hydrolysis by UvsX protein.

T4EndonucleaseV is a bifunctional DNA glycosylase that exhibits both DNA N-glycosylase and AP lyase activities. It is capable of repairing cyclobutane pyrimidine dimers induced by ultraviolet (UV) radiation in DNA.

T4 Phage β-glucosyltransferase is a DNA-modifying enzyme encoded by T4 phage, which facilitates the transfer of glucose from uridine diphosphate glucose to the 5-hydroxymethylcytosine bases in phage T4 DNA.

T4endonucleaseVII exhibits broad substrate specificity, enabling it to bind and cleave both DNA duplexes and single-base mismatches in three- and four-way branched DNA structures.

T4 lysozyme, derived from recombinant E.coli strains, is capable of lysing bacterial cell walls. It targets the peptidoglycan of bacterial cell walls, hydrolyzing the β-1,4 bond between N-acetylmuramic acid and N-acetylglucosamine.

Dextran T4 (MW 4,000) is a glucose polymer with an average molecular weight of 4000. It exhibits excellent biodegradability and biocompatibility, making it suitable for applications in food, pharmaceuticals, cosmetics, and research fields.

T4-BSA is a hapten-carrier protein conjugate formed by coupling T4 to bovine serum albumin (BSA). As a hapten, T4 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. T4-BSA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

T4-OVA is a hapten-carrier protein conjugate formed by coupling T4 to chicken ovalbumin (OVA). As a hapten, T4 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.T4-OVA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.

Thyroxine sulfate is a sulfoconjugated derivative of Thyroxine and is also a metabolite of Thyroxine.

(T-4)-Copper(1+), bis[2,9-bis(4-methoxyphenyl)-1,10-phenanthroline-κN1,κN10]-, chloride is a reagent used in biochemical reactions.

D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.

Dextrothyroxine sodium is the dextrorotary isomer of thyroxine.

L-Thyroxine sodium xhydrate is a synthetic thyroid hormone used in the treatment of hypothyroidism.

XUN49524 also known as Vezf1-IN-T4, is an inhibitor of the pro-angiogenic activity of the zinc finger transcription factor Vezf1. XUN49524 was first reported in Molecules (2018), 23(7), 1615/1-1615/15 . This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane, a PEG-derived PROTAC linker, is used for PROTAC synthesis[1].

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs).

N-Methyl-N-(t-Boc)-PEG4-acid, a polyethylene glycol (PEG) derivative, is used as a PROTAC linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2/FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].

Biotin-PEG4-amino-t-Bu-DADPS-C3-alkyne serves as a PEG-based linker for PROTAC synthesis [1].