sulfotransferase

Expression system: E. coli
Length: 1-102, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 40-556, Partial of Isoform 2
Activity: Not Tested

Expression system: E. coli
Length: 41-431, Lumenal Domain
Activity: Not Tested

Expression system: E. coli
Length: 1-291, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-291, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-299, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 38-411, Partial
Activity: Not Tested

Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cytoplasmic protein and exists as a homodimer. SULT1A2 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and might thus participate as a modulating factor of cancer risk.

Sulfotransferase 1C2 (SULT1C2) is a cytosolic enzyme member of the Sulfotransferase 1 family. Human SULT1C2 is primarily expressed in the adult stomach, kidney and thyroid gland, and in the fetal kidney and liver. SULT1C2 catalyzes the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. SULT1C2 may be involved in the activation of carcinogenic hyroxylamines. It shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).

Expression system: E. coli
Length: 1-284, Full Length
Activity: Not Tested

HS3ST1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36 kDa and the accession number is AAH57803.1.

Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.

Sulfotransferase family cytosolic 2B member 1, also known as Sulfotransferase 2B1, ST2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, SULT2B1 and HSST2, is a cytoplasm protein that belongs to the sulfotransferase 1 family. The human hydroxysteroid sulfotransferase (SULT) family is comprised of two subfamilies, SULT2A1 and SULT2B1. SULT2B1 is expressed highly in placenta, prostate and trachea. A lesser expression of SULT1B1 was observed in the small intestine and lung. SULT2B1 catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. SULT2B1 sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol. The two SULT2B1 isoforms, SULT2B1a and SULT2B1b, are encoded by a single gene as a result of alternative transcription initiation and alternative splicing. SULT2B1b catalyzes the sulfonation of 3beta-hydroxysteroid hormones and cholesterol, whereas SULT2B1a preferentially catalyzes pregnenolone sulfonation.

Expression system: E. coli
Length: 2-296, Partial
Activity: Enzyme Activity

Expression system: E. coli
Length: 2-294, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 99-561, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 26-370, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 39-472, Partial
Activity: Not Tested

Expression system: E. coli
Length: 2-295, Partial
Activity: Not Tested

Expression system: E. coli
Length: 2-295, Partial
Activity: Enzyme Activity

Expression system: Baculovirus Insect Cells
Length: 36-347, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 27-395, Lumenal Domain
Activity: Not Tested

CHST9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.66 kDa and the accession number is NP_113610.2.