stereoisomer

Cebranopadol ((1α,4α) stereoisomer) is a stereoisomer of cebranopadol, a potent ORL-1 agonist.

NVP-CGM097 (stereoisomer) is a non-bioactive form of NVP-CGM097, a highly potent and selective MDM2 inhibitor.

ISA-2011B-P2 is a stereoisomer of ISA-2011B, a potent PIP5K1α inhibitor with antitumor activity.

(Iso)-WAY-260022 ((Iso)-NRI-022) is a stereoisomer of WAY-260022, a norepinephrine reuptake inhibitor and selective inhibitor of 5-hydroxytryptamine and dopamine transport proteins.

Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.

H-D-Trp-OH (D-Tryptophan) is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the marine venom peptide).

D-Glutamine is the D-type stereoisomer of cell-permeable glutamine, one of the 20 amino acids encoded by the standardized genetic code.

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.

Spirostan-3-ol (Sarsaponin) is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis.

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, a BET bromodomain inhibitor, which acts on BRD4(1 2) with IC50 values of 77 nM and 33 nM in a cell-free assay.

exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt β-catenin signaling pathway.

L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine, which is derived from L-isoleucine in vivo, can be used for the diagnosis of maple syrup urine disease (MSUD), a genetic disorder. Indeed, plasma L-alloisoleucine levels above 5 μmol L is the most specific and most sensitive diagnostic marker for all forms of MSUD.

S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensive animal models.

(2S,4S)-Sacubitril (Sacubitril Impurity C) is a stereoisomer derived from Sacubitril which is a potent NEP inhibitor.

D-Citrulline (H-D-Cit-OH), a stereoisomer of L-citrulline, effectively reduces cardiac contractile dysfunction caused by polymorphonuclear leukocyte (PMN) in isolated perfused rat hearts undergoing ischemia reperfusion. This protective effect is mediated through a non-NO-mediated mechanism.

2-Deoxy-L-ribose is the stereoisomer of 2-Deoxy-D-ribose and can inhibit the anti-apoptotic effects of 2-Deoxy-D-ribose. Additionally, 2-Deoxy-L-ribose is capable of suppressing tumor cell metastasis by downregulating thymidine phosphorylase overexpression.

(R)-CCG-1423 is a stereoisomer of CCG-1423. CCG-1423 is a Rho inhibitor involved in blocking signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF).

(S)-CCG-1423 is a stereoisomer of CCG-1423. CCG-1423 is a Rho inhibitor involved in blocking signaling through myocardin-related transcription factor A and serum response factor.

Dilevalol, the RR-stereoisomer of labetalol, is a non-cardioselective beta-adrenoceptor antagonist with substantial partial beta 2-agonist and negligible alpha 1-blocking activity.

Idonic acid is a stereoisomer of gluconic acid.

10(R)-PAHSA is a stereoisomer of 10-PAHSA , an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).

10(S)-PAHSA is a stereoisomer of 10-PAHSA , an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).

9(R)-PAHSA is a stereoisomer of 9-PAHSA , an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).