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Cat No. | Product Name | Synonyms | Targets |
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T8452 | Dantrolene | Others | |
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. | |||
T1065 | Baclofen | Lioresal | GABA Receptor |
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp... | |||
T1308 | Orphenadrine hydrochloride | Mebedrol,Mephenamin | Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor |
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. | |||
T6618 | Orphenadrine Citrate | Flexon,Flexoject,Banflex | AChR , iGluR |
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. | |||
T1092 | Zolmitriptan | 311C90,BW-311C90 | 5-HT Receptor |
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and... | |||
T8630 | Baclofen hydrochloride | 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride | GABA Receptor |
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe... | |||
T6355 | (R)-baclofen | STX209,Arbaclofen | GABA Receptor |
(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity. | |||
T11986L | Mebeverine acid hydrochloride | ||
Mebeverine acid hydrochloride is an effective, oral compound to act directly on the smooth muscle of the gastrointestinal tract to relieve spasticity symptoms. | |||
T72023 | JB002 | Myosin | |
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy. | |||
T0077 | Dantrolene sodium | Lapatinib ditosylate monohydrate,Dantrolene sodium salt | Others , Calcium Channel |
Dantrolene sodium (Lapatinib ditosylate monohydrate) salt is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neu... | |||
T67952 | JB062 | Myosin | |
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se... | |||
T28657 | SAD-448 | ||
SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor. | |||
T21077 | Tolperisone free base | Mydeton,Atmosgen free base,Mideton,Menopatol,Besnoline free base,Mydocalm | |
Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm. | |||
T29117 | VSN-16 | VSN-16R,VSN 16R,VSN16R | |
VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis. | |||
T17306 | (R)-Baclofen hydrochloride | Arbaclofen hydrochloride | GABA Receptor |
Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to spinal cord damage. It acts at spinal and supraspinal site... | |||
T73439 | MPH-220 | ||
MPH-220 is a selective, orally active skeletal muscle myosin-2 inhibitor that facilitates muscle relaxation. As an anti-spastic agent, it holds potential for research into spasticity and muscle stiffness. |
Cat No. | Product Name | Synonyms | Targets |
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T5295 | 1-Hydroxyoctadecane | 1-Octadecanol,Stearyl alcohol,Octadecanol | Others , Endogenous Metabolite |
1-Hydroxyoctadecane (OctadecanolOctadecanol) is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardation, a... |
Cat No. | Product Name | Species | Expression System |
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TMPY-03282 | FUCA1 Protein, Human, Recombinant (His) | Human | HEK293 |
FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in FUCA1 gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal stor... | |||
TMPY-01876 | HSP60 Protein, Human, Recombinant (His & GST) | Human | E. coli |
HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins ... | |||
TMPY-02752 | SPG21 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
Spastic paraplegia 21 (SPG21), also known as acid Cluster Protein 33 (ACP33) and Mast syndrome protein, is a member of the AB hydrolase superfamily. Human SPG21 is a 38 amino acid residue protein widely expressed in all ... | |||
TMPY-01057 | SPG21 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Spastic paraplegia 21 (SPG21), also known as acid Cluster Protein 33 (ACP33) and Mast syndrome protein, is a member of the AB hydrolase superfamily. Human SPG21 is a 38 amino acid residue protein widely expressed in all ... | |||
TMPY-02091 | GAD67 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of thegroup II decarboxylase family. GAD1 is expressed in benign and malignant ... | |||
TMPY-01479 | SPG3A Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin... | |||
TMPY-01924 | HSP60 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins ... |