solubilizing

NSC-639829 is an anti-tumor compound that requires a solubilizing agent for dissolution.

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

Dicaprylyl carbonate (Dimethyl carbonate) is a solid fat derived from plants and a dry emollient. Dimethyl carbonate has good skin compatibility and comprehensive properties, such as a sunscreen filter with the ability to dissolve and disperse.

Sodium laureth sulfate (Sodium lauryl polyoxyethylene ether sulfate) is an anionic surfactant, with excellent decontamination, wetting, emulsification, dispersion, solubilizing performance and foaming property.

GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM). The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.

Gentisic acid ethanolamide serves as a complexing agent in pharmaceutical injectables. It is also utilized as a solubilizing agent in certain formulations and acts as a preservative.

Epothilone F is a derivative or analogue of Epothilone D. Epothilone F is also an active metabolite of Epothilone D. In molecule of Epothilone F, a hydroxymethyl group is on the thiazole ring. Like taxanes, Epothilone F prevents cancer cells from dividing

UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapidly hydrolysed under physiological c

Lauryl maltose neopentyl glycol (LMNG) is a detergent that solubilizes and stabilizes membrane proteins by extracting intact proteins from membranes, thereby enhancing the stability of entities such as G protein-coupled receptors and respiratory system complexes. LMNG exhibits a significant solubilizing effect.

1. Rubusoside is a natural sweetener . 2. Rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties.

RG33 Peptide, utilized in type 2 diabetes (T2D) research [1], enhances glucose clearance in insulin-resistant mice and facilitates cholesterol efflux in cultured macrophages by effectively solubilizing lipid vesicles.

Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide group. Serving as a building block in Solid Phase Peptide Synthesis (SPPS), it is utilized in the helping hand strategy for purifying highly insoluble peptides. The solubilizing residue is attached to the lysine side chain through click chemistry. The solubilization tag can be removed with a 1M solution of hydrazine or hydroxylamine.

Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent featuring an azide group. This SPPS building block is utilized in the helper strategy for purifying highly insoluble peptides. The solubilizing residue is attached to the lysine side chain through click chemistry. The solubility tag can be removed using a 1M solution of hydrazine or hydroxylamine.

Succinyl-β-cycloaltrin is a modified cyclodextrin distinguished by unique chemical properties, enhancing its role as an effective solubilizing and stabilizing agent in various compounds, particularly within the pharmaceutical sector. With its hydrophobic interior and hydrophilic exterior, Succinyl-β-cycloaltrin forms stable inclusion complexes with hydrophobic molecules like drugs and nutrients. This interaction improves their solubility and bioavailability, making them more effective for therapeutic or nutritional applications.

C7BzO (Dimethyl-2-hydroxyethylampropanepropanesulfonate) is a highly effective solubilizing detergent suitable for samples from bacteria, mammals, and plants. It is used for protein extraction and preparation of samples for two-dimensional gel electrophoresis.

Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is a chemically modified cyclodextrin with effective solubilizing properties. It is widely used in compound formulations to enhance solubility and bioavailability. Additionally, Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate aids in improving the release characteristics of compounds.

PEG10000 (Polyethylene glycol 10000) is utilized as a solubilizing agent and can be employed as a biomaterial or organic compound in life sciences research.

(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) (α‐HPCD (MW 1180)) is a cyclic oligosaccharide derivative that serves as a solubilizing agent in various experiments.

Polyethylene glycol tert-octylphenyl ether X-405 is a nonionic surfactant widely employed in both industrial and research settings. Belonging to the polyethylene glycol (PEG) ether family, this compound features a hydrophilic head and a lipophilic tail, making it suitable for use in emulsions, detergents, and solubilizers. Notably beneficial in membrane protein studies, it aids in dissolving and stabilizing proteins for structural analysis. Moreover, Polyethylene glycol tert-octylphenyl ether X-405 is utilized in various applications, such as drug delivery systems, nanotechnology, and diagnostic analysis. Due to its emulsifying and solubilizing properties, it is also used in the production of microemulsions, ointments, and lotions. It is important to note that ingestion or inhalation of this compound can be toxic, necessitating proper handling and safety precautions.

Octyl-POE is capable of solubilizing membrane proteins and has a critical micelle concentration (CMC) of 6.6 mM.