solani

3-Methoxyphenylacetic acid belongs to the class of organic compounds known as anisoles. 3-Methoxyphenylacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa).3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot

4-Deacetylneosolaniol is a useful organic compound for research related to life sciences. The catalog number is T124276 and the CAS number is 74833-39-9.

Solanidine, a cholestane alkaloid isolated from potato species [Solanum spp.], exhibits antitumor effects by inhibiting cell proliferation.

Solanidiene (Solanthrene) is isolated from the leaves of S. tuberosum (potato plant).

Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.

α-Solanine (alpha-Solanine) is an alkaloid derived from potato with anticancer and antitumor activity, attenuating chondrocyte death by inhibiting the NF-κB pathway. α-Solanine inhibits the proliferation and migration of glioma cells but promotes apoptosis of glioma cells.

1. Isoeugenol acetate (Acetylisoeugenol) shows good antifungal activities against R. solani and F. oxysporum. 2. Isoeugenol acetate is a mild sensitizer in vivo.

Validamycin A is an antibiotic and fungicide that inhibits the alginate enzyme trehalase and thus protects crops from the fungus Rhizoctonia solani, as well as being a reversible inhibitor of tyrosinase.

Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50= 1 μM) and protein levels of IL-2 in Jurkat cells (IC50= 5.2 μM).1 1.Rether, J., Serwe, A., Anke, T., et al.Inhibition of inducible tumor necrosis factor-α expression by the fungal epipolythiodiketopiperazine gliovirinBiol. Chem.388(6)627-637(2007) 2.Howell, C.R., and Stipanovic, R.D.Gliovirin, a new antibiotic from Gliocladium virens, and its role in the biological control of Pythium ultimumCan. J. Microbiol.29(3)321-324(1983) 3.Iwatsuki, M., Otoguro, K., Ishiyama, A., et al.In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationshipsJ. Antibiot. (Tokyo)63(10)619-622(2010)

Fumiquinazoline D is a fungal metabolite originally isolated from A. fumigatus that has activity against Gram-positive and Gram-negative bacteria (MICs = 8-16 μg/ml) as well as F. solani and C. albicans fungi (MICs = 32 and 64 μg/ml, respectively).

Globosuxanthone A, a dihydroxanthenone with anticancer activity, exhibits significant antifungal activity against Fusarium graminearum, Fusarium solani, and Botrytis cinerea, with MIC values of 4, 8, and 16 μg mL, respectively [1] [2].

Kievitone, an isoflavanone, can be isolated from the hypocotyls of Phaseolus vulgaris L. (common bean) infected with Rhizoctonia solani Kühn. It exhibits both antifungal and antitumor activities [1] [2].

Cytosporone C, an antifungal metabolite produced by the Diaporthe eucalyptorum fungus associated with Melia azedarach, demonstrates antifungal efficacy against Alternaria solani [1].

Chaetosemin J, a metabolite with antifungal properties, effectively inhibits the growth of plant pathogenic fungi including Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, demonstrating minimum inhibitory concentration (MIC) values between 12.5-25 μM [1].

Monaschromone, a polyketide metabolite, effectively suppresses the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, demonstrating minimum inhibitory concentration (MIC) values between 6.25 and 12.5 μM [1].

Eugenitol (Compound 3), an antifungal metabolite extracted from Diaporthe eucalyptorum, exhibits inhibitory properties against four plant pathogenic fungi: Alternaria solani, Botrytis cinerea, Fusarium solani, and Gibberella saubinettii [1].

D-calycanthine has antifungal activity, it shows significant inhibitory activities against five plant pathogenic fungi Exserohilum turcicum, Bipolaris maydis, Alternaria solani, Sclerotinia sderotiorum, and Fusarium oxysportium.

Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug ml concentration.

Harzianopyridone is an atpenin-like compound that functions as an inhibitor of mammalian and nematode mitochondrial complex II, also known as succinate:ubiquinone oxidoreductase (SQR), demonstrating IC50 values of 0.017, 0.2, and 2 μM against bovine, rat, and nematode complex II, respectively. Additionally, it inhibits nematode quinol-fumarate reductase (QFR) with an IC50 value of 0.36 μM. Significantly selective for complex II over complexes I and III in rats and cattle, as well as complex I in nematodes, with IC50 values exceeding 100 μM, it exhibits notable antibacterial and antifungal properties, with EC50 values of 35.9, 42.2, 60.4, and 50.2 μg/ml against R. solani, S. rolfsii, M. phaseolina, and F. oxysporum, respectively.

Dihydroaeruginoic acid, an antibiotic sourced originally from P. fluorescens, exhibits antimicrobial efficacy in disc assays against diverse pathogens, including R. solani, P. ultimum, B. cinerea, S. rolfsii, C. gloeosporioides, F. oxysporum, and S. tritici fungi, along with B. subtilis, E. herbicola, and S. albus bacteria, at a concentration of 200 μg/disc.

Sporothriolide, a metabolite produced by Nodulisporium sp. A21, demonstrates potent antifungal activity against R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. It also inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo [1].

Cryptosporiopsin A is a polyketide that has been found in Cryptosporiopsis and has antifungal activity. It is active against the plant pathogenic fungus P. viticola and the plant pathogenic fungi A. cochliodes, P. ultimum, and R. solani (MICs = 20, 40, and 50 µg ml, respectively).