solani

3-Methoxyphenylacetic acid belongs to the class of organic compounds known as anisoles. 3-Methoxyphenylacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa).3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot

4-Deacetylneosolaniol is a useful organic compound for research related to life sciences. The catalog number is T124276 and the CAS number is 74833-39-9.

Solanidine, a cholestane alkaloid isolated from potato species [Solanum spp.], exhibits antitumor effects by inhibiting cell proliferation.

Solanidiene (Solanthrene) is isolated from the leaves of S. tuberosum (potato plant).

Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.

α-Solanine (alpha-Solanine) is an alkaloid derived from potato with anticancer and antitumor activity, attenuating chondrocyte death by inhibiting the NF-κB pathway. α-Solanine inhibits the proliferation and migration of glioma cells but promotes apoptosis of glioma cells.

1. Isoeugenol acetate (Acetylisoeugenol) shows good antifungal activities against R. solani and F. oxysporum. 2. Isoeugenol acetate is a mild sensitizer in vivo.

Validamycin A is an antibiotic and fungicide that inhibits the alginate enzyme trehalase and thus protects crops from the fungus Rhizoctonia solani, as well as being a reversible inhibitor of tyrosinase.

Benzyl propionate exhibits broad-spectrum antifungal activity against pathogens such as Phyllosticta zingiberi, Fusarium solani, and Magnaporthe oryzae, and is a key inhibitory compound produced by the strain ETR-B22 against various fungal pathogens.

Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50= 1 μM) and protein levels of IL-2 in Jurkat cells (IC50= 5.2 μM).1 1.Rether, J., Serwe, A., Anke, T., et al.Inhibition of inducible tumor necrosis factor-α expression by the fungal epipolythiodiketopiperazine gliovirinBiol. Chem.388(6)627-637(2007) 2.Howell, C.R., and Stipanovic, R.D.Gliovirin, a new antibiotic from Gliocladium virens, and its role in the biological control of Pythium ultimumCan. J. Microbiol.29(3)321-324(1983) 3.Iwatsuki, M., Otoguro, K., Ishiyama, A., et al.In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationshipsJ. Antibiot. (Tokyo)63(10)619-622(2010)

Fumiquinazoline D is a fungal metabolite originally isolated from A. fumigatus that has activity against Gram-positive and Gram-negative bacteria (MICs = 8-16 μg/ml) as well as F. solani and C. albicans fungi (MICs = 32 and 64 μg/ml, respectively).

Globosuxanthone A, a dihydroxanthenone with anticancer activity, exhibits significant antifungal activity against Fusarium graminearum, Fusarium solani, and Botrytis cinerea, with MIC values of 4, 8, and 16 μg/mL, respectively [1] [2].

Kievitone, an isoflavanone, can be isolated from the hypocotyls of Phaseolus vulgaris L. (common bean) infected with Rhizoctonia solani Kühn. It exhibits both antifungal and antitumor activities [1] [2].

Cytosporone C, an antifungal metabolite produced by the Diaporthe eucalyptorum fungus associated with Melia azedarach, demonstrates antifungal efficacy against Alternaria solani [1].

Chaetosemin J, a metabolite with antifungal properties, effectively inhibits the growth of plant pathogenic fungi including Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, demonstrating minimum inhibitory concentration (MIC) values between 12.5-25 μM [1].

Monaschromone, a polyketide metabolite, effectively suppresses the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, demonstrating minimum inhibitory concentration (MIC) values between 6.25 and 12.5 μM [1].

Eugenitol (Compound 3), an antifungal metabolite extracted from Diaporthe eucalyptorum, exhibits inhibitory properties against four plant pathogenic fungi: Alternaria solani, Botrytis cinerea, Fusarium solani, and Gibberella saubinettii [1].

Validamycin A (Standard) is the standard substance of Validamycin A, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Validamycin A is an antibiotic and fungicide that inhibits the alginate enzyme trehalase and thus protects crops from the fungus Rhizoctonia solani, as well as being a reversible inhibitor of tyrosinase.

Cuevaene A can be isolated from the Streptomyces genus gdmAI-disrupted LZ35 strain. It exhibits moderate activity against Gram-positive bacteria, such as Bacillus subtilis (strain ATCC 11060), and demonstrates moderate activity against fungi, including Fusarium verticillioides (strain S68) and Rhizoctonia solani (strain GXE4).

Cuevaene B can be isolated from the Streptomyces genus gdmAI-disrupted LZ35 strain. This compound exhibits moderate activity against Gram-positive bacteria, such as Bacillus subtilis (strain ATCC 11060), and shows moderate activity against fungi, including Fusarium verticillioides (strain S68) and Rhizoctonia solani (strain GXE4).

Calycanthine is a natural alkaloid exhibiting central nervous system toxicity, capable of inducing convulsions and seizures.

Fusaproliferin is a diterpene mycotoxin identified in Fusarium solani. Fusaproliferin can reverse Lipopolysaccharides stimulation and the NF-κB and MAPKs signaling pathways, thus playing a role in anti-inflammatory processes. It has affinity for the TLR4 protein with a KD value of 28.6 μM. Fusaproliferin exhibits cytotoxicity against pancreatic cancer, showing rapid submicromolar IC50 effects.

Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug/ml concentration.

Harzianopyridone is an atpenin-like compound that functions as an inhibitor of mammalian and nematode mitochondrial complex II, also known as succinate:ubiquinone oxidoreductase (SQR), demonstrating IC50 values of 0.017, 0.2, and 2 μM against bovine, rat, and nematode complex II, respectively. Additionally, it inhibits nematode quinol-fumarate reductase (QFR) with an IC50 value of 0.36 μM. Significantly selective for complex II over complexes I and III in rats and cattle, as well as complex I in nematodes, with IC50 values exceeding 100 μM, it exhibits notable antibacterial and antifungal properties, with EC50 values of 35.9, 42.2, 60.4, and 50.2 μg/ml against R. solani, S. rolfsii, M. phaseolina, and F. oxysporum, respectively.