signaling lymphocytic activation molecule

Expression system: HEK293 Cells
Length: 21-237, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 25-242, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 22-220, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 22-220, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 48-454, Extracellular Domain
Activity: Not Tested

CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. CD84 expression has been documented on several hematopoietic cell types, including monocytes, macrophages, dendritic cells, B lymphocytes, and platelets. Activation of cell surface CD84 initiates a signaling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation, which in turn enhances cell survival. Either immunoneutralization or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.

Mouse SLAM family member 9(Slamf9) is a single-pass type I membrane protein. The SLAMF9 gene encodes a member of the signaling lymphocytic activation molecule family. The encoded protein is a cell surface molecule that consists of two extracellular immunoglobulin domains, a transmembrane domain and a short cytoplasmic tail that lacks the signal transduction motifs found in other family members. The slamf9 protein may play a role in the immune response.

Expression system: HEK293 Cells
Length: 20-221, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 48-454, Partial
Activity: Not Tested

SLAM CD150 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.3 kDa and the accession number is A6JG08.

Expression system: HEK293 Cells
Length: 1-258, Partial
Activity: ELISA

Expression system: E. coli
Length: 2-97, Partial
Activity: ELISA

SLAM CD150 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is D3ZAD7.