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Cat No. | Product Name | Synonyms | Targets |
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T35606 | 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium | 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) | |
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors. 1,2-Dioleoyl-sn-glycero-3-ph... | |||
T32902 | L-Serine-1-13C | L-(1-13C)Serine,L-(l-13C)Serine | |
L-Serine-1-13C is an amino acid. | |||
T33097 | Lysyl-serine | ||
Lysyl-serine is a bioactive chemical. | |||
T40889 | DMNB-caged-Serine | ||
DMNB-caged-Serine is a photocaged amino acid . DMNB is a caging group which is sensitive to blue light. DMNB-caged-Serine can be incorporated into proteins in Saccharomyces cerevisiae in response to the amber nonsense co... | |||
T36065 | N-Oleoyl-L-Serine | ||
Bone mass and shape is continuously remodeled by the concerted and balanced action of osteoblasts (bone forming cells) and osteoclasts (bone-resorbing cells). The endocannabinoid system plays an essential role in the mai... | |||
T33098 | Lysyl-tyrosyl-serine acetate | ||
Lysyl-tyrosyl-serine acetate is a bioactive chemical. | |||
T66681 | Glycyl-l-serine | ||
Glycyl-l-serine is a useful organic compound for research related to life sciences. The catalog number is T66681 and the CAS number is 7361-43-5. | |||
T65211 | N-Cbz-DL-serine | ||
N-Cbz-DL-serine is a useful organic compound for research related to life sciences. The catalog number is T65211 and the CAS number is 2768-56-1. | |||
T66044 | DL-Serine Hydrazide Hydrochloride | ||
DL-Serine Hydrazide Hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66044 and the CAS number is 55819-71-1. | |||
T78174 | Serine Hydrolase inhibitor-21 | Others | |
Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for Alzheimer's disease research [1]. | |||
T66377 | N-Cbz-D-serine Methyl Ester | ||
N-Cbz-D-serine Methyl Ester is a useful organic compound for research related to life sciences. The catalog number is T66377 and the CAS number is 93204-36-5. | |||
T8350 | TPCK | Proteasome | |
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis | |||
T78617 | N-Acetylserine | N-Acetyl-L-serine | Endogenous Metabolite |
N-Acetylserine (N-Acetyl-L-serine) serves as the physiological inducer of cysteine biosynthesis by binding to the CysB apoprotein and stimulating cysJIH transcription in vitro [1] [2]. | |||
TP1277 | Bradykinin | Endogenous Metabolite , Bradykinin Receptor | |
Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol... | |||
T63847 | 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium | ||
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product obtained through NADPH oxidase activation and Lyso-PS signal transduction. Oleoyl-2-hydroxy-sn-glycero-3phospho-L-serine sodiu... | |||
T11666 | IPR-803 | Serine/threonin kinase | |
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM. | |||
T13408 | ZK824190 | Others , Serine Protease | |
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively). | |||
T11885 | LSP-249 | Others | |
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. | |||
T10547 | BioE-1115 | Serine/threonin kinase , Casein Kinase | |
BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM). | |||
T4058 | R-IMPP | Others , Serine/threonin kinase | |
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. | |||
T7017 | WNK463 | Serine/threonin kinase | |
WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4). | |||
T13257 | Upamostat | PAI-1 , Serine/threonin kinase , Serine Protease | |
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor. | |||
T25495 | Hexadecylphosphoserine | Hexadecylphospho-L-serine,Hexadecyl phosphoserine,Hexadecyl-phosphoserine | |
Hexadecylphosphoserine is a representative growth inhibitor. | |||
T4524 | SBC-110736 | SBC110736 | Others , Serine/threonin kinase |
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor | |||
T8362 | Benzamidine hydrochloride | Benzamidine HCl | Serine/threonin kinase , Serine Protease |
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively). | |||
T9920 | Evolocumab | Others | |
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9). | |||
T8645 | PF-06446846 | Others | |
PF 06446846 is a potent and selective PCSK9 inhibitor | |||
T14358 | Avoralstat | BCX4161 | Others |
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. | |||
T9276 | SBC-115337 | Others , Serine/threonin kinase | |
SBC-115337 is a PCSK9 inhibitor. | |||
T2626 | SBC-115076 | SBC115076 | Others , Serine/threonin kinase |
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. | |||
T21761 | HNMPA | IGF-1R | |
HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote... | |||
T5456 | WNK-IN-11 | Allosteric WNK Kinase Inhibitor | Serine/threonin kinase |
WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM) | |||
T6370 | AEBSF hydrochloride | AEBSF HCl,Pefabloc SC | Thrombin , Serine Protease , Influenza Virus |
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin. | |||
T8676 | FOY 251 | Others , Serine/threonin kinase , SARS-CoV | |
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate. | |||
T31206 | Darexaban | YM 150,Darexaban, Tanexaban,YM150 | Factor Xa |
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati... | |||
T3359 | Aprotinin | Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin | Others , Serine Protease , Influenza Virus , Proteasome |
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat... | |||
T2392 | Nafamostat mesylate | FUT-175 | Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease |
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | |||
T3990 | AA26-9 | Phospholipase , Serine Protease | |
AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase. | |||
T8574 | SPHINX | Others | |
SPHINX is a new generation inhibitor of SPRK1 | |||
T8866 | GW779439X | Apoptosis , Antibacterial , CDK , Aurora Kinase | |
GW779439X is an inhibitor of CDK. | |||
T19763 | Cetraxate hydrochloride | DV-1006,DV 1006,Cetraxate HCl,DV1006 | Serine/threonin kinase |
Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect. | |||
T8936 | Proteinase K | proteinase K for tritirachium album,Protease K | Others |
Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c... | |||
T15802 | LY2183240 | FAAH , Autophagy | |
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM). | |||
T1954 | SRPIN340 | SRPK inhibitor | Virus Protease , Serine/threonin kinase |
SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM). | |||
T2391 | Camostat mesylate | FOY-S980,FOY305,Camostat mesilate | Serine/threonin kinase , SARS-CoV , Sodium Channel |
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function. | |||
T40495 | Elastase from porcine pancreas | EC 3.2.1.35 | Others |
Porcine pancreatic elastase is a serine protease composed of a single polypeptide chain with 240 amino acid residues. It has the ability to hydrolyze polypeptides and proteins, and can induce emphysema in hamsters. | |||
T5194 | SPHINX31 | Serine/threonin kinase | |
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM). | |||
T5125 | LY3200882 | TGF-beta/Smad | |
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). | |||
T50103 | NFAT Inhibitor-2 | Others | |
NFAT Inhibitor-2 is a compound used as a molecular building block. | |||
T9374 | AA38-3 | 1-Piperidinecarboxylic acid, 4-nitrophenyl ester | FAAH , Lipase , MAGL |
AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH) |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8394 | D-Serine | (R)-Serine | Endogenous Metabolite , NMDAR , iGluR |
D-Serine ((R)-Serine) is an endogenous amino acid,is a potent co-agonist at the NMDA glutamate receptor. | |||
T2O2730 | L-Serine | (S)-Serine,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid | Endogenous Metabolite |
L-Serine (serine) is a non-essential amino acid in humans, L-Serine is present and functionally important in many proteins.L-Serine is also found at the active site of the serine protease enzyme class that includes tryps... | |||
T8363 | DL-Serine | PKM | |
DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. | |||
T1324 | O-Phospho-L-serine | L-Serine O-phosphate,Phosphoserine,Dexfosfoserine,L-SOP | Amino Acids and Derivatives , Endogenous Metabolite , GluR , NMDAR |
O-Phospho-L-serine (Phosphoserine) is the phosphoric acid ester of serine. | |||
T4722 | O-Acetyl-L-serine hydrochloride | Others , Endogenous Metabolite | |
O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in humans arises from either microbial metaboli... | |||
TQ0158 | Azaserine | CI-337,P-165,O-Diazoacetyl-L-serine | Others , Antibiotic |
Azaserine (CI-337) is a tumor-inhibiting antibiotic isolated from a species of Streptomyces and functions as an inhibitor of glutamine amidotransferase. | |||
T5057 | DL-O-Phosphoserine | DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP | Others , Endogenous Metabolite |
DL-O-Phosphoserine (DL-SOP), a normal metabolite in human biofluid, is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by kinases during cell signaling ... | |||
T8095 | O-Acetylserine | O-Acetyl-L-serine | Others , Endogenous Metabolite |
O-Acetylserine (O-Acetyl-L-serine) (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the cysteine in bacteria and plants. | |||
TN2082 | Pinostrobin | Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF | |
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... | |||
T5S0689 | Demethylwedelolactone | Serine Protease | |
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells. | |||
T4757 | L-Homoserine | (S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID | Others , Endogenous Metabolite |
L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer t... | |||
T1589 | D-Cycloserine | RO-1-9213 | Others , Antibacterial , Antibiotic , iGluR |
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents. | |||
T7054 | N-Benzoyl-(2R,3S)-3-phenylisoserine | taxol side chain | Antiviral |
N-Benzoyl-(2R,3S)-3-phenylisoserine (taxol side chain) is an intermediate in the preparation of potent anticancer drug Paclitaxel, used to study the location of the binding sites. It shows cytotoxic, antiviral and immuno... | |||
T0710 | L-Cycloserine | Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone | HIV Protease , GABA Receptor |
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G... | |||
T4704 | L-Anserine nitrate | L-Anserine nitrate salt | Others , Endogenous Metabolite |
L-Anserine nitrate (L-Anserine nitrate salt) is a dipeptide found in most animal tissues. In model systems it is a potent Antioxidant and scavener of hydroxyl radicals. The compound inhibits nonenzymatic protein glycatio... | |||
T19440 | N-(3-Oxooctanoyl)-DL-homoserine lactone | (Rac)-3-oxo-C8-HSL | Others |
N-(3-Oxooctanoyl)-DL-homoserine lactone with stereochemistry-dependent growth regulatory activity for roots . | |||
T40583 | N-(3-Oxotetradecanoyl)-DL-homoserine lactone | 3-Oxo-C14-AHL,N-(3-Oxotetradecanoyl)-DL-homoserine lactone | |
N-(3-Oxotetradecanoyl)-DL-homoserine lactone, part of the N-Acyl homoserine lactone (AHL) family derived from gram-negative bacteria, serves as a quorum sensing (QS) signaling molecule. | |||
T81722 | N-(3-Oxodecanoyl)-L-homoserine lactone | 3-Oxo-C10-HSL | |
N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) functions as a bacterial quorum-sensing signal autoinducer [1]. | |||
T35577 | Phosphatidylserines (bovine) | ||
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th... | |||
T7444 | 6-(Dimethylamino)purine | N,N-Dimethyladenine | Serine/threonin kinase , CDK |
6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor | |||
T5085 | Pyridoxal 5'-phosphate hydrate | Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate | Others , Endogenous Metabolite |
Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synth... | |||
T9143 | D-Isoleucine | (2R,3R)-2-Amino-3-methylpentanoic acid,(R)-Isoleucine | Others |
D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine. | |||
T4915 | β-Glycerophosphate disodium salt hydrate | Phosphatase , Endogenous Metabolite | |
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func... | |||
T4713 | Phosphorylcholine chloride calcium salt tetrahydrate | Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate | Others , Endogenous Metabolite |
Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc... | |||
TN6872 | Trypsin | Protease-activated Receptor | |
Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T4825 | D-(+)-Xylose | D(+)-Xylose,(+)-Xylose,Wood sugar | Endogenous Metabolite |
D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopo... | |||
T24412 | Lipoxamycin | G 26146,G-26146,G26146,Neoenactin M1 | |
Lipoxamycin is an inhibitor of serine palmitoyl-transferase. | |||
T19365 | Hydroxypyruvic acid | 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid | Others |
Hydroxypyruvic acid is an intermediate in the metabolism of glycine, serine, and threonine. It is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. | |||
T75648 | Rivulariapeptolides 1155 | ||
Rivulariapeptolides 1155 is a potent serine protease inhibitor, exhibiting inhibitory concentrations (IC50s) of 41.84 nM, 4.94 nM, and 56.54 nM against chymotrypsin, elastase, and proteinase K, respectively [1]. | |||
T16381 | Okadaic acid | Others | |
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted fr... | |||
T75652 | Molassamide B | ||
Molassamide B, a serine protease inhibitor, exhibits potent inhibitory activity, as evidenced by its IC50 values of 24.65 nM against chymotrypsin, 11.69 nM against elastase, and 5.42 nM against proteinase K [1]. | |||
T75649 | Rivulariapeptolides 1185 | ||
Rivulariapeptolides 1185, a highly potent and selective serine protease inhibitor, exhibits IC50 values of 13.17 nM for chymotrypsin, 23.59 nM for elastase, and 55.26 nM for proteinase K [1]. | |||
T75651 | Rivulariapeptolides 988 | ||
Rivulariapeptolides 988 demonstrates significant potency and selectivity as a serine protease inhibitor, exhibiting IC50 values of 95.46 nM for chymotrypsin, 15.29 nM for elastase, and 85.50 nM for proteinase K [1]. | |||
T75650 | Rivulariapeptolides 1121 | ||
Rivulariapeptolides 1121 is a potent and selective serine protease inhibitor, demonstrating IC50 values of 35.52 nM for chymotrypsin, 13.24 nM for elastase, and 48.05 nM for proteinase K [1]. | |||
T16165 | Myriocin | ISP-I,Thermozymocidin | HCV Protease , Antifungal |
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour g... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03468 | D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO) | Salmonella heidelberg | E. coli |
TMPY-02078 | HtrA2/Omi Protein, Human, Recombinant (His) | Human | E. coli |
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ... | |||
TMPY-02731 | SPINK4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPY-01897 | PRSS3 Protein, Human, Recombinant (His) | Human | HEK293 |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on... | |||
TMPY-05159 | Granzyme A/GZMA Protein, Human, Recombinant (His) | Human | HEK293 |
Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 cells. | |||
TMPY-01059 | BMPR2 Protein, Human, Recombinant (His) | Human | HEK293 |
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin... | |||
TMPY-04997 | Prostasin/PRSS8 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from hu... | |||
TMPJ-00484 | SHMT1 Protein, Human, Recombinant (His) | Human | Human Cells |
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to g... | |||
TMPH-02083 | Serine racemase/SRR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Serine racemase/SRR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-04928 | TMPRSS11B Protein, Human, Recombinant (His) | Human | HEK293 |
TMPY-00274 | Enterokinase Protein, Bovine, Recombinant (His) | Bovine | Yeast |
TMPY-04985 | TMPRSS11D Protein, Human, Recombinant (His) | Human | HEK293 |
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated ... | |||
TMPH-02643 | Enteropeptidase Protein, Mouse, Recombinant (His & Myc) | Mouse | HEK293 |
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in... | |||
TMPH-02553 | BSSP-4 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
BSSP-4 Protein, Mouse, Recombinant (His) is expressed in E. coli. | |||
TMPY-00817 | Granzyme B/GZMB Protein, Human, Recombinant (His) | Human | HEK293 |
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ... | |||
TMPJ-01320 | BSSP-4 Protein, Human, Recombinant (His) | Human | Human Cells |
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c... | |||
TMPY-00905 | Prostasin/PRSS8 Protein, Human, Recombinant (His) | Human | HEK293 |
Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from hu... | |||
TMPY-05026 | RISC Protein, Human, Recombinant (His) | Human | HEK293 |
TMPH-02644 | Enteropeptidase Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in... | |||
TMPY-04500 | RISC Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TMPY-04407 | LOK Protein, Human, Recombinant (His) | Human | E. coli |
Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and STE2 subfamily. Protein kinases constitute a... | |||
TMPY-04466 | STK40 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to... | |||
TMPY-04374 | MST4 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains ... | |||
TMPJ-01253 | Serpin A3N Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, an... | |||
TMPY-02117 | Marapsin Protein, Human, Recombinant (His) | Human | HEK293 |
The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasi... | |||
TMPJ-01282 | Serpin B12 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f... | |||
TMPY-04468 | STK16 Protein, Human, Recombinant (His & NusA) | Human | E. coli |
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is... | |||
TMPY-04934 | Serpin A3n Protein, Rat, Recombinant (His) | Rat | HEK293 |
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal ... | |||
TMPY-01580 | PRSS2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists... | |||
TMPY-00588 | HAI-1/SPINT1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
TMPH-01175 | CBS Protein, Human, Recombinant (His) | Human | Yeast |
CBS Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPY-04398 | MST1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The t... | |||
TMPH-01174 | CBS Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
CBS Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPY-03330 | BPHL Protein, Human, Recombinant (His) | Human | E. coli |
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrola... | |||
TMPH-00986 | CORIN Protein, Human, Recombinant (His) | Human | E. coli |
CORIN Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-05786 | SPINK4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPH-02615 | CBS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cystei... | |||
TMPY-02783 | Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His) | Mouse | Baculovirus-Insect Cells |
Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from hu... | |||
TMPJ-01203 | HATL5 Protein, Human, Recombinant (His) | Human | Human Cells |
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease tha... | |||
TMPH-03457 | CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) | Saccharomyces cerevisiae | E. coli |
TMPJ-00490 | Serpin A5 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i... | |||
TMPH-00340 | ATG1 Protein, Candida glabrata, Recombinant (His) | Candida glabrata | E. coli |
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein ... | |||
TMPY-00163 | SPINK2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein ... | |||
TMPJ-00980 | Complement Factor MASP3 Protein, Human, Recombinant (His) | Human | Human Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro... | |||
TMPJ-00557 | Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) | Human | Human Cells |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di... | |||
TMPY-04626 | Enterokinase/EK Protein, Bovine, Recombinant | Bovine | P. pastoris |
Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the ... | |||
TMPY-04230 | HAI-2/SPINT2 Protein, Human, Recombinant (His) | Human | HEK293 |
Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI... | |||
TMPY-00926 | HAI-2/SPINT2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI... | |||
TMPH-03456 | CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) | Saccharomyces cerevisiae | Baculovirus |
TMPJ-00944 | PPP1CC Protein, Human, Recombinant (His) | Human | E. coli |
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractil... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L1400 | MAPK Inhibitor Library | 367 compounds | |
A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L4100 | TGF-beta/Smad Compound Library | 185 compounds | |
A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; | |||
L1300 | PI3K-AKT-mTOR Compound Library | 425 compounds | |
A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; |