Search Result

Search Results for " regulator "

Targets

IL Receptor

210

Compounds

Natural Products

657

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T12218	NFAT Transcription Factor Regulator-1		IL Receptor
	NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).		IL Receptor
T60000	STING (WT/R232) activity regulator 126		STING
	STING (WT/R232) activity regulator 126 is a STING modulator with antibacterial and antiviral effects.		STING
T77804	KRAS G12D mutation regulator 4

T82450	ER proteostasis regulator-1
	ER Proteostasis Regulator-1 (Compound 481) is a potent modulator of endoplasmic reticulum proteostasis with research applications in Alzheimer's disease and diabetes [1].
T5637	Triflumuron		Others
	Triflumuron is an insecticide belonging to the group of so-called insect growth regulators. It inhibits the synthesis of chitin by the insect larvae, causing the die.		Others
T3135	KM11060		CFTR , Autophagy
	KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane.		CFTR , Autophagy
T4384	Halofenozide		Others
	Halofenozide is an ecdysteroid agonist and used as a pesticide.		Others
T1805	Ataluren	PTC124	CFTR , Autophagy
	Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and olde...		CFTR , Autophagy
T1634	Glibenclamide	Glyburide	Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy
	Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T14898	CCG-63808		GTPase
	CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.		GTPase
T16681	Nesolicaftor	PTI-428	CFTR , Autophagy
	Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.		CFTR , Autophagy
T9499	Icenticaftor	QBW251	CFTR
	Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.		CFTR
T11438	GNE-1858		Others , MAPK
	GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA).		Others , MAPK
T14935	Elexacaftor	VX-445	CFTR , Autophagy
	Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.		CFTR , Autophagy
T14897	CCG-63802		GTPase
	CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.		GTPase
T5312	CFTR corrector 2	FDL169	CFTR , Autophagy
	CFTR corrector 2 (FDL169) is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.		CFTR , Autophagy
T2451	GlyH-101	GlyH 101	CFTR , Autophagy
	GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.		CFTR , Autophagy
T1874	PPQ-102	PPQ102,CFTR Inhibitor,PPQ 102	CFTR , Autophagy
	PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).		CFTR , Autophagy
T2588	Ivacaftor	Ivacaftor (VX-770),VX-770	CFTR , Autophagy
	Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.		CFTR , Autophagy
T2486	IOWH-032	IOWH032,IOWH 032	CFTR , Autophagy
	IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.		CFTR , Autophagy
T7083	GLPG1837	ABBV-974	CFTR , Autophagy
	GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.		CFTR , Autophagy
T10591	BPO-27 racemate	BPO-27 (racemate)	CFTR , Autophagy
	BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.		CFTR , Autophagy
T2595	Lumacaftor	VX-809,VRT 826809	CFTR , Autophagy
	Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).		CFTR , Autophagy
T3495	Tasimelteon	VEC-162,BMS-214778	Melatonin Receptor , MT Receptor
	Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.		Melatonin Receptor , MT Receptor
T2355	CFTR(inh)-172	CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172	CFTR , Autophagy
	CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.		CFTR , Autophagy
T6434	CCG-50014	CCG 50014	GTPase
	CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.		GTPase
T2263	Tezacaftor	VX661	CFTR , Autophagy
	Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.		CFTR , Autophagy
TP2340	Hemoregulatory peptide 5b	hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide
	Hemoregulatory peptide 5b is a synthetic analog of granulocyte chalone which initially identified in extracts of rodent bone marrow and human leukocytes. Monomer inhibits both formations of GM-CFC colonies and cytotoxic ...
T20341	DNDS		CFTR
	DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).		CFTR
T7864	Chlorpropham		Others
	Chlorpropham acts as a plant growth regulator and herbicide.		Others
T10545	BIO-32546		PDE
	BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.		PDE
T22736	DMeOB	3,3'-Dimethoxybenzaldazine	GluR
	DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.		GluR
T1832	Walrycin B		Antibacterial , Antibiotic
	Walrycin B is a new-type antibacterial compound targeting the WalR response regulator.		Antibacterial , Antibiotic
T5914	Folcisteine	3-Acetylthiazolidine-4-carboxylic acid	Others
	Folcisteine (3-Acetylthiazolidine-4-carboxylic acid) is a kind of plant growth regulator.		Others
T20738	Chlormequat chloride	NSC 34858,NSC34858,EI 38,555,NSC-34858,EI-38,555,EI38,555	Others
	Chlormequat chloride (EI 38,555), a plant growth regulator, is widely applied in agriculture because it can promote sturdier growth of the crops.		Others
T77612	WAY-620472		PPAR
	WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.		PPAR
T17216	Valspodar	PSC 833	P-gp
	Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.		P-gp
T5560	Dicyclanil		Others
	Dicyclanil, a regulator of insect growth, is a veterinary medicine for the protection against early-season myiasis.		Others
T19821	Methoxyfenozide		Others
	Methoxyfenozide is an insect growth regulator. Methoxyfenozide used in the control of lepidopteran insect pests.		Others
T13809	P62-mediated mitophagy inducer	PMI	Mitophagy
	P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy .		Mitophagy
T16044	Methoprene	ZR-515	Others
	Methoprene (ZR-515) is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or r...		Others
T63806	CFTR corrector 8		CFTR
	CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic...		CFTR
T12896L	Shepherdin 79-87 acetate	Shepherdin 79-87 acetate (861224-28-4 free base)	HSP , Survivin
	Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.		HSP , Survivin
T77344	IcFSP1		Apoptosis
	icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.		Apoptosis
T60066	Thermospermine	N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine,1,12-Diamino-4,8-diazadodecane	Others
	Thermospermine is a structural isomer of spermine and plays a role in the repression of xylem differentiation. Thermospermine can be used in studies about acting as a plant growth regulator and serving in the control of ...		Others
T19822	RH-5849	RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine	Others
	RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) is a novel Insect growth regulator that can be used as a potential insecticide to control olive fruit fly.		Others
T11734	K-80003	TX-803	Akt , RAR/RXR
	K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.		Akt , RAR/RXR
T15711	Larazotide acetate		Gap Junction Protein
	Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.		Gap Junction Protein
T13667L1	Dusquetide aceate	Dusquetide aceate (931395-42-5 Free base)	Antibacterial
	Dusquetide aceate is an innate immune defense regulator against damage-associated molecular patterns and pathogen-associated molecular patterns. Dusquetide aceate shows anti-inflammation and antibacterial activities.		Antibacterial
T29856	Aleplasinin	PAZ 417,PAZ417,PAZ-417	PAI-1
	Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...		PAI-1

Compounds

NFAT Transcription Factor Regulator-1

T12218

Synonym:

Target: IL Receptor

STING (WT/R232) activity regulator 126

T60000

Synonym:

Target: STING

KRAS G12D mutation regulator 4

T77804

Synonym:

Target:

ER proteostasis regulator-1

Target: CFTR, Autophagy

Target: CFTR, Autophagy

Glibenclamide

T1634

Synonym: Glyburide

Target: Potassium Channel, Mitochondrial Metabolism, CFTR, P-gp, Autophagy

Target: CFTR, Autophagy

Target: CFTR, Autophagy

Target: CFTR, Autophagy

GlyH-101

T2451

Synonym: GlyH 101

Target: CFTR, Autophagy

PPQ-102

T1874

Synonym: PPQ102,CFTR Inhibitor,PPQ 102

Target: CFTR, Autophagy

Ivacaftor

T2588

Synonym: Ivacaftor (VX-770),VX-770

Target: CFTR, Autophagy

IOWH-032

T2486

Synonym: IOWH032,IOWH 032

Target: CFTR, Autophagy

GLPG1837

T7083

Synonym: ABBV-974

Target: CFTR, Autophagy

BPO-27 racemate

T10591

Synonym: BPO-27 (racemate)

Target: CFTR, Autophagy

Lumacaftor

T2595

Synonym: VX-809,VRT 826809

Target: CFTR, Autophagy

Tasimelteon

T3495

Synonym: VEC-162,BMS-214778

Target: Melatonin Receptor, MT Receptor

CFTR(inh)-172

T2355

Synonym: CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172

Target: CFTR, Autophagy

Target: CFTR, Autophagy

Hemoregulatory peptide 5b

TP2340

Synonym: hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide

Synonym: 3,3'-Dimethoxybenzaldazine

Target: Antibacterial, Antibiotic

Folcisteine

T5914

Synonym: 3-Acetylthiazolidine-4-carboxylic acid

Target: Others

Chlormequat chloride

T20738

Synonym: NSC 34858,NSC34858,EI 38,555,NSC-34858,EI-38,555,EI38,555

P62-mediated mitophagy inducer

Shepherdin 79-87 acetate

T12896L

Synonym: Shepherdin 79-87 acetate (861224-28-4 free base)

Target: HSP, Survivin

Synonym: N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine,1,12-Diamino-4,8-diazadodecane

Target: Others

RH-5849

T19822

Synonym: RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine

Target: Gap Junction Protein

Dusquetide aceate

T13667L1

Synonym: Dusquetide aceate (931395-42-5 Free base)

Target: Antibacterial

Aleplasinin

T29856

Synonym: PAZ 417,PAZ417,PAZ-417

Target: PAI-1

Cat No.	Product Name	Synonyms	Targets
T3719	Daminozide	Succinic Acid,DMASA,Aminozide	Histone Demethylase
	Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.		Histone Demethylase
T3764	1-Triacontanol	Myricyl alcohol,1-Triacontanol,Melissyl alcohol,Well-Bloom,Miraculan,Lithospermoside,triacontan-1-ol	Others
	1-Triacontanol (Melissyl alcohol) is an active biochemical		Others
T7220	Prohydrojasmon racemate	Propyl dihydrojasmonate,Prohydrojasmon	Others
	Prohydrojasmon racemate (Propyl dihydrojasmonate) is a synthesized plant gowth regulator, which has jasmonic acid activity.		Others
TN1545	D-Tyrosine		Tyrosinase
	D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits biofilm formation and induces the self-dispersal of biofilm...		Tyrosinase
TN2100	Pratensein		Others , NF-κB
	Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.		Others , NF-κB
T5040	Medroxyprogesterone		Estrogen/progestogen Receptor , Progesterone Receptor
	Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.		Estrogen/progestogen Receptor , Progesterone Receptor
T5571	Forchlorfenuron	Forchlorfenuron (KT-30, CPPU)	Others
	Forchlorfenuron (Forchlorfenuron (KT-30, CPPU)) is plant growth regulator and cytokinin; can be used to increase fruit size of fruits.		Others
T5086	Pharmatose DCL 14	D-Lactose monohydrate	Others , Endogenous Metabolite
	Pharmatose DCL 14 (D-Lactose monohydrate) is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Pharmatose DCL 14 is also an important osmotic regulator ...		Others , Endogenous Metabolite
TN6750	2-tert-Butyl-1,4-benzoquinone		Nrf2
	2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.		Nrf2
T5514	Epibrassinolide	24-Epibrassinolide,B1105,BP55	Apoptosis
	Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mammalian steroids.		Apoptosis
T0845	Cyromazine	CGA-72662,Cyromazin	Others , Endogenous Metabolite
	Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.		Others , Endogenous Metabolite
T5663	α-Lactose	Lactose	Others
	α-Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osmotic regulator of lactation.		Others
T4819	Pipecolic acid	(±)-Piperidine-2-carboxylic acid,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline	Others , Endogenous Metabolite , Antibacterial
	Pipecolic acid (2-Piperidinecarboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike.		Others , Endogenous Metabolite , Antibacterial
T3879	Silychristin	Silicristin	Lipoxygenase
	Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.		Lipoxygenase
T19458	N-Hydroxypipecolic acid	1-Hydroxy-2-piperidinecarboxylic acid,NHP	Others
	N-Hydroxypipecolic acid (NHP) is a plant metabolite and a systemic acquired resistance (SAR) regulator.		Others
T0069	Uracil		Others , Endogenous Metabolite
	Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synt...		Others , Endogenous Metabolite
T20945	2,4-D	Hedonal,Macondray,2,4-D acid,Chloroxone	DNA/RNA Synthesis
	2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti...		DNA/RNA Synthesis
T3414	Morroniside		Apoptosis , MMP , Pyroptosis
	Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...		Apoptosis , MMP , Pyroptosis
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T4938	Potassium 1H-indol-3-yl sulfate	Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate	AhR , Endogenous Metabolite
	Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm...		AhR , Endogenous Metabolite
T40450	Dihydrojasmonic acid
	Dihydrojasmonic acid is a plant growth regulator.
T19457	N-Hydroxypipecolic acid potassium	NHP potassium,1-Hydroxy-2-piperidinecarboxylic acid potassium	Others
	N-Hydroxypipecolic acid potassium is a metabolite of plant and a systemic acquired resistance (SAR) regulator.		Others
T13503	31-Norlanostenol		Others
	31-Norlanostenol is a triterpene isolated from the latex of Euphorbia officinarum. It can act as an efficient insect growth regulator on S. frugiperda and Tenebrio molitor.		Others
T27807	13-Methyltetradecanoic acid	LeDSF3
	LeDSF3 is a regulator of the biosynthesis of the antifungal polycyclic tetramate macrolactam HSAF in Lysobacter enzymogenes and anti-tumor agent. LeDSF3 down-regulates p-AKT and activates caspase-3.
T71795	Norstictic acid
	Norstictic acid is a potent, selective allosteric transcriptional regulator that exhibits anticancer, antioxidant, and antimicrobial activities.
T73815	TMC-205
	TMC-205, a natural fungal metabolite, exhibits antiproliferative effects against cancer cell lines and functions as a transcriptional up-regulator of the SV40 promoter [1].
TN1775	Isocryptotanshinone		ERK , JNK , STAT
	Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of ...		ERK , JNK , STAT
T75524	Mutabilol
	Mutabilol, also known as compound 1, is a natural product derived from the leaves of Plectranthus mutabilis that acts as a potent regulator of P-glycoprotein (P-gp). It has been shown to increase P-gp expression in NCI-H...
TN6198	Mahanine
	Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can r...
T75600	Coronatine
	Coronatine is a plant growth regulator synthesized by Pseudomonas syringae, mimicking bioactive jasmonic acid conjugates or octadecanoid signal molecules in higher plants, which induces pathogenic symptoms. It enhances t...
T36489	Malformin A
	Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhib...

Natural Products

Daminozide

T3719

Synonym: Succinic Acid,DMASA,Aminozide

Target: Histone Demethylase

1-Triacontanol

T3764

Synonym: Myricyl alcohol,1-Triacontanol,Melissyl alcohol,Well-Bloom,Miraculan,Lithospermoside,triacontan-1-ol

Target: Others

Prohydrojasmon racemate

T7220

Synonym: Propyl dihydrojasmonate,Prohydrojasmon

Target: Others, NF-κB

Medroxyprogesterone

T5040

Synonym:

Target: Estrogen/progestogen Receptor, Progesterone Receptor

Forchlorfenuron

T5571

Synonym: Forchlorfenuron (KT-30, CPPU)

Target: Others

Pharmatose DCL 14

T5086

Synonym: D-Lactose monohydrate

Target: Others, Endogenous Metabolite

2-tert-Butyl-1,4-benzoquinone

Synonym: 24-Epibrassinolide,B1105,BP55

Target: Apoptosis

Cyromazine

T0845

Synonym: CGA-72662,Cyromazin

Target: Others, Endogenous Metabolite

Synonym: (±)-Piperidine-2-carboxylic acid,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline

Target: Others, Endogenous Metabolite, Antibacterial

N-Hydroxypipecolic acid

T19458

Synonym: 1-Hydroxy-2-piperidinecarboxylic acid,NHP

Target: Others, Endogenous Metabolite

2,4-D

T20945

Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone

Target: DNA/RNA Synthesis

Morroniside

T3414

Synonym:

Target: Apoptosis, MMP, Pyroptosis

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Potassium 1H-indol-3-yl sulfate

T4938

Synonym: Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate

Target: AhR, Endogenous Metabolite

N-Hydroxypipecolic acid potassium

T19457

Synonym: NHP potassium,1-Hydroxy-2-piperidinecarboxylic acid potassium

13-Methyltetradecanoic acid

Target: ERK, JNK, STAT

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00744	CsrA Protein, E. coli, Recombinant	E. coli	E. coli
	A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress...
TMPY-04918	CNPY4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CNPY4 belongs to the canopy family. CNPY4 interacts with toll-like receptor 4 (TLR4) and plays a role in the regulation of the cell surface expression of TLR4. Toll-like receptors (TLRs) recognize microbial products and ...
TMPY-02714	PRC1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PRC1 (protein regulator of cytokinesis 1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. It is essential for controlling the spatiotemporal formation of the...
TMPY-03179	CNPY4 Protein, Human, Recombinant (His)	Human	HEK293
	CNPY4 belongs to the canopy family. CNPY4 interacts with toll-like receptor 4 (TLR4) and plays a role in the regulation of the cell surface expression of TLR4. Toll-like receptors (TLRs) recognize microbial products and ...
TMPY-01125	MDMX Protein, Human, Recombinant (His)	Human	E. coli
	MDM4 (MDM4 Regulator Of P53, also known as MDMX) is a Protein Coding gene. This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus and shows str...
TMPY-01800	NEGR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Neuronal Growth Regulator 1, NEGR1, also known as neurotractin, or KILON, belongs to the immunoglobulin superfamily, IgLON family. This GPI-linked cell surface glycoprotein NEGR1 is composed of three Ig-like domains and ...
TMPY-03185	METRN Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	METRN (Meteorin, Glial Cell Differentiation Regulator) is a Protein Coding gene. The encoded protein belongs to the meteorin family. It is broadly expressed in the brain, kidney, and other tissues. Meteorin is a novel se...
TMPH-02520	BCL2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a fee...
TMPY-03980	ECD Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	ECD, also known as ecdysoneless homolog, belongs to the SGT1 family. It is highly expressed in muscle and heart. ECD is a novel promoter of mammalian cell cycle progression. This function is related to its ability to re...
TMPH-01279	CRACR2B Protein, Human, Recombinant (His)	Human	E. coli
	Plays a role in store-operated Ca(2+) entry (SOCE).
TMPH-03245	BCL2 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a fee...
TMPY-01913	NEGR1 Protein, Human, Recombinant (His)	Human	HEK293
	Neuronal Growth Regulator 1, NEGR1, also known as neurotractin, or KILON, belongs to the immunoglobulin superfamily, IgLON family. This GPI-linked cell surface glycoprotein NEGR1 is composed of three Ig-like domains and ...
TMPY-03964	CGREF1 Protein, Human, Recombinant (His)	Human	HEK293
	CGREF1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 31.3 kDa. Accession number: Q99674-1
TMPY-00138	CNPY3 Protein, Human, Recombinant (hFc)	Human	HEK293
	CNPY3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 53.7 kDa. Accession number: Q9BT09-1
TMPY-05005	CNPY3 Protein, Human, Recombinant (His)	Human	HEK293
	CNPY3 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 28.5 kDa. Accession number: A0A7U3JW12
TMPY-03395	PC4/SUB1 Protein, Human, Recombinant (His)	Human	E. coli
	SUB1 belongs to the transcriptional coactivator PC4 family. It is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptio...
TMPY-03261	CNPY2 Protein, Human, Recombinant (His)	Human	HEK293
	CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light cha...
TMPY-00226	CNPY3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CNPY3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 53.9 kDa. Accession number: Q9DAU1-1
TMPJ-01192	ELAPOR1 Protein, Human, Recombinant (His)	Human	Human Cells
	Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated wi...
TMPY-00596	CNPY3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CNPY3 Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 28.6 kDa. Accession number: Q9DAU1-1
TMPY-02924	RGS1 Protein, Human, Recombinant (His)	Human	E. coli
	RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization o...
TMPJ-00717	BAG2 Protein, Human, Recombinant (His)	Human	E. coli
	BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is...
TMPJ-00584	Bc1-w Protein, Human, Recombinant (His)	Human	E. coli
	Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing thre...
TMPY-04058	RGS5 Protein, Human, Recombinant (His)	Human	E. coli
	RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins ha...
TMPH-01003	ATG14 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidyletha...
TMPH-02535	BAG3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleoti...
TMPH-02534	BAG3 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleoti...
TMPH-01208	DEAF1 Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid respon...
TMPH-01606	BAG6 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which main...
TMPH-01605	BAG6 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which main...
TMPH-01828	Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E2 (His & Myc)	HPV 11	E. coli
	Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites,...
TMPH-01829	Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)	HPV 11	E. coli
	ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins....
TMPY-03564	TSPAN8 Protein, Human, Recombinant (His)	Human	HEK293
	Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPH-00010	MMP-14 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tiss...
TMPJ-00235	TPO Protein, Human, Recombinant (His)	Human	Human Cells
	Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me...
TMPY-03484	TCPTP Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1...
TMPY-01870	IL-9 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thy...
TMPY-01121	DKK3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p...
TMPJ-00135	BDNF Protein, Human/Murine/Rat, Recombinant	Human,Mouse,Rat	E. coli
	Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPY-00925	SOST Protein, Human, Recombinant (His)	Human	HEK293
	Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima...
TMPY-01633	SOST Protein, Rat, Recombinant (His)	Rat	HEK293
	Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima...
TMPY-00654	ACVR2B Protein, Human, Recombinant (hFc)	Human	HEK293
	ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01883	EPOR Protein, Human, Recombinant (His)	Human	HEK293
	Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific ...
TMPY-00548	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-01296	HGFR/c-Met Protein, Human, Recombinant (His)	Human	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-03630	MZB1/PERP1 Protein, Human, Recombinant (His)	Human	HEK293
	MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion an...
TMPY-05423	C-MPL Protein, Rat, Recombinant (hFc)	Rat	HEK293
	CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPY-03195	Serum Amyloid P Protein, Human, Recombinant (His)	Human	HEK293
	Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identifie...
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CsrA Protein, E. coli, Recombinant

TMPH-00744

Species: E. coli

Expression System: E. coli

CNPY4 Protein, Mouse, Recombinant (His)

TMPY-04918

Species: Mouse

Expression System: HEK293

PRC1 Protein, Human, Recombinant (His)

TMPY-02714

Species: Human

Expression System: Baculovirus-Insect Cells

CNPY4 Protein, Human, Recombinant (His)

TMPY-03179

Species: Human

Expression System: HEK293

MDMX Protein, Human, Recombinant (His)

TMPY-01125

Species: Human

Expression System: E. coli

NEGR1 Protein, Mouse, Recombinant (His)

TMPY-01800

Species: Mouse

Expression System: HEK293

METRN Protein, Mouse, Recombinant (hFc)

TMPY-03185

Species: Mouse

Expression System: HEK293

BCL2 Protein, Mouse, Recombinant (His)

TMPH-02520

Species: Mouse

Expression System: E. coli

ECD Protein, Human, Recombinant (His & GST)

TMPY-03980

Species: Human

Expression System: Baculovirus-Insect Cells

CRACR2B Protein, Human, Recombinant (His)

TMPH-01279

Species: Human

Expression System: E. coli

BCL2 Protein, Rat, Recombinant (His)

TMPH-03245

Species: Rat

Expression System: in vitro E. coli expression system

NEGR1 Protein, Human, Recombinant (His)

TMPY-01913

Species: Human

Expression System: HEK293

CGREF1 Protein, Human, Recombinant (His)

TMPY-03964

Species: Human

Expression System: HEK293

CNPY3 Protein, Human, Recombinant (hFc)

TMPY-00138

Species: Human

Expression System: HEK293

CNPY3 Protein, Human, Recombinant (His)

TMPY-05005

Species: Human

Expression System: HEK293

PC4/SUB1 Protein, Human, Recombinant (His)

TMPY-03395

Species: Human

Expression System: E. coli

CNPY2 Protein, Human, Recombinant (His)

TMPY-03261

Species: Human

Expression System: HEK293

CNPY3 Protein, Mouse, Recombinant (hFc)

TMPY-00226

Species: Mouse

Expression System: HEK293

ELAPOR1 Protein, Human, Recombinant (His)

TMPJ-01192

Species: Human

Expression System: Human Cells

CNPY3 Protein, Mouse, Recombinant (His)

TMPY-00596

Species: Mouse

Expression System: HEK293

RGS1 Protein, Human, Recombinant (His)

TMPY-02924

Species: Human

Expression System: E. coli

BAG2 Protein, Human, Recombinant (His)

TMPJ-00717

Species: Human

Expression System: E. coli

Bc1-w Protein, Human, Recombinant (His)

TMPJ-00584

Species: Human

Expression System: E. coli

RGS5 Protein, Human, Recombinant (His)

TMPY-04058

Species: Human

Expression System: E. coli

ATG14 Protein, Human, Recombinant (His & Myc)

TMPH-01003

Species: Human

Expression System: E. coli

BAG3 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02535

Species: Mouse

Expression System: E. coli

BAG3 Protein, Mouse, Recombinant (His)

TMPH-02534

Species: Mouse

Expression System: Yeast

DEAF1 Protein, Human, Recombinant (His)

TMPH-01208

Species: Human

Expression System: E. coli

BAG6 Protein, Human, Recombinant (His & Myc)

TMPH-01606

Species: Human

Expression System: Baculovirus

BAG6 Protein, Human, Recombinant (E. coli, His & Myc)

TMPH-01605

Species: Human

Expression System: E. coli

Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E2 (His & Myc)

TMPH-01828

Species: HPV 11

Expression System: E. coli

Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)

TMPH-01829

Species: HPV 11

Expression System: E. coli

TSPAN8 Protein, Human, Recombinant (His)

TMPY-03564

Species: Human

Expression System: HEK293

MMP-14 Protein, Human, Recombinant (His & SUMO)

TMPH-00010

Species: Human

Expression System: E. coli

TPO Protein, Human, Recombinant (His)

TMPJ-00235

Species: Human

Expression System: Human Cells

TCPTP Protein, Human, Recombinant

TMPY-03484

Species: Human

Expression System: Baculovirus-Insect Cells

IL-9 Protein, Human, Recombinant (His)

TMPY-01870

Species: Human

Expression System: Baculovirus-Insect Cells

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

TMPJ-00607

Species: Mouse

Expression System: Human Cells

DKK3 Protein, Mouse, Recombinant (His)

TMPY-01121

Species: Mouse

Expression System: HEK293

BDNF Protein, Human/Murine/Rat, Recombinant

TMPJ-00135

Species: Human,Mouse,Rat

Expression System: E. coli

SOST Protein, Human, Recombinant (His)

TMPY-00925

Species: Human

Expression System: HEK293

SOST Protein, Rat, Recombinant (His)

TMPY-01633

Species: Rat

Expression System: HEK293

ACVR2B Protein, Human, Recombinant (hFc)

TMPY-00654

Species: Human

Expression System: HEK293

ACVR2B Protein, Mouse, Recombinant (His)

TMPY-01281

Species: Mouse

Expression System: HEK293

EPOR Protein, Human, Recombinant (His)

TMPY-01883

Species: Human

Expression System: HEK293

HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-00548

Species: Cynomolgus,Rhesus

Expression System: HEK293

HGFR/c-Met Protein, Human, Recombinant (His)

TMPY-01296

Species: Human

Expression System: HEK293

MZB1/PERP1 Protein, Human, Recombinant (His)

TMPY-03630

Species: Human

Expression System: HEK293

C-MPL Protein, Rat, Recombinant (hFc)

TMPY-05423

Species: Rat

Expression System: HEK293

Serum Amyloid P Protein, Human, Recombinant (His)

TMPY-03195

Species: Human

Expression System: HEK293

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Cat No.	Product Name
L8500	HIF-1 Signaling Pathway Compound Library	1352 compounds
	A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L1300	PI3K-AKT-mTOR Compound Library	425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L4300	Wnt/Hedgehog/Notch Compound Library	240 compounds
	A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;

Libraries

HIF-1 Signaling Pathway Compound Library

L8500

Compounds: 1352

PI3K-AKT-mTOR Compound Library

L1300

Compounds: 425

Wnt/Hedgehog/Notch Compound Library

L4300

Compounds: 240