Search Result

Search Results for " regulated "

Targets

SGK

160

Compounds

Natural Products

581

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T6635	EMD638683		SGK
	EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).		SGK
T2431	ID-8	ID8	DYRK
	ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.		DYRK
TQ0111	LDN-192960		DYRK , Haspin Kinase
	LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).		DYRK , Haspin Kinase
T15422	GSK-626616		DYRK
	GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia.		DYRK
T9977	SGK1-IN-4		SGK
	SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.		SGK
T6257	AZ191		DYRK
	AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.		DYRK
T2622	GSK 650394	GSK650394	SGK , Influenza Virus
	GSK 650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.		SGK , Influenza Virus
T11447	GNF4877		GSK-3 , DYRK
	GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.		GSK-3 , DYRK
T5358	Longdaysin		ERK , Casein Kinase , CDK
	Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 µM). It also can inhibit ERK2 (IC50: 52 µM).		ERK , Casein Kinase , CDK
T40187	GNF2133		DYRK
	GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.		DYRK
T14980	CLK-IN-T3		DYRK , CDK
	CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.		DYRK , CDK
T10479	BAY885		ERK
	BAY885 is a new ERK5 inhibitor.		ERK
T14360	AX-15836		ERK
	AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).		ERK
TQ0005	KO-947		ERK
	KO-947 is a potent and specific inhibitor of ERK1/2 kinases.		ERK
T6066	SCH772984		ERK , MEK
	SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.		ERK , MEK
T14894	CC-90003		ERK
	CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.		ERK
T5535	ERK5-IN-2		ERK
	ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.		ERK
T6818	DEL-22379	DEL22379	Apoptosis , ERK
	DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.		Apoptosis , ERK
T5184	ERK5-IN-1		ERK
	ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).		ERK
T1956	FR 180204	FR180204	Apoptosis , ERK
	FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.		Apoptosis , ERK
T6511	Ravoxertinib	GDC-0994	ERK
	Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).		ERK
T10429	Tizaterkib	AZD-0364	ERK
	Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.		ERK
T4091	Temuterkib	LY3214996	ERK
	Temuterkib (LY3214996) is a potent and selective, orally available inhibitor of the extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity.		ERK
T36674	DMU-212		Apoptosis , ERK
	DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2...		Apoptosis , ERK
T39695	ARD-2128		Androgen Receptor
	ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protein levels, suppressing AR-regulated gene expression in tumor...		Androgen Receptor
T6948	Pluripotin	SC1	ERK , Raf , S6 Kinase
	Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.		ERK , Raf , S6 Kinase
T14364	AZ-Dyrk1B-33	3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine	DYRK
	AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.		DYRK
T1843	XMD8-92		ERK , BMI-1 , Epigenetic Reader Domain
	XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).		ERK , BMI-1 , Epigenetic Reader Domain
T12069	MK-8353	SCH900353	ERK
	MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)		ERK
T8901	YUM70		Apoptosis , GPR , HSP
	YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediate...		Apoptosis , GPR , HSP
T21295	BIX02189	BIX 02189	ERK , MEK
	BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).		ERK , MEK
T11224	Rineterkib	ERK-IN-1	ERK , Raf
	Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.		ERK , Raf
T2029	Bohemine		ERK , CDK
	Bohemine is a cyclin-dependent kinase inhibitor.		ERK , CDK
T9141	ERK-IN-3	ASN007 free base	ERK
	ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.		ERK
T4496	LM22B-10	LM22B10	ERK , Trk receptor , Akt
	LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo.		ERK , Trk receptor , Akt
T1842	XMD17-109	XMD17 109,ERK5-IN-1	ERK
	XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).		ERK
T7506	Yoda 1		Piezo Channel
	Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)		Piezo Channel
T8472	ERK1/2 inhibitor 2	ASTX-029,ASTX029	ERK
	ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.		ERK
T5364	TBHQ	tert-Butylhydroquinone	Apoptosis , ERK , Others , Ferroptosis , Nrf2 , Autophagy
	TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.		Apoptosis , ERK , Others , Ferroptosis , Nrf2 , Autophagy
T2623	PD98059	PD 98059	ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
	PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhibits autophagy.		ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
T3166	VX-11e	Vertex-11e,VTX-11e,TCS ERK 11e	ERK , GSK-3 , FLT , CDK , Aurora Kinase
	VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.		ERK , GSK-3 , FLT , CDK , Aurora Kinase
T7005	Ulixertinib	BVD-523,VRT752271	ERK
	Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.		ERK
T1144L	Lidocaine Hydrochloride hydrate		EGFR , Sodium Channel
	Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.		EGFR , Sodium Channel
T27242	EF24	EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone	ERK , MEK , Caspase
	EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral ...		ERK , MEK , Caspase
T4092	AG126	Tyrphostin AG126,AG 126	ERK , COX
	AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expres...		ERK , COX
T0468	Lidocaine	Lignocaine,Alphacaine,Xylocaine	Apoptosis , ERK , NF-κB , MEK , Sodium Channel , Histamine Receptor
	Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammat...
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...		S1P Receptor , LPL Receptor
T9776	TRPM4 inhibitor 8		TRP/TRPV Channel
	TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.		TRP/TRPV Channel
T4636	Protein kinase inhibitors 1		Others , DYRK
	Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.		Others , DYRK
T19913	CKI-7	CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl	ROCK , SGK , Casein Kinase , CDK , S6 Kinase
	CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.		ROCK , SGK , Casein Kinase , CDK , S6 Kinase

Compounds

Target: DYRK, Haspin Kinase

Target: SGK, Influenza Virus

Target: ERK, Casein Kinase, CDK

Target: Apoptosis, ERK

Target: Apoptosis, ERK

Target: Apoptosis, ERK

ARD-2128

T39695

Synonym:

Target: Androgen Receptor

Pluripotin

T6948

Synonym: SC1

Target: ERK, Raf, S6 Kinase

AZ-Dyrk1B-33

T14364

Synonym: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

Target: ERK, BMI-1, Epigenetic Reader Domain

Target: Apoptosis, GPR, HSP

Synonym: ASN007 free base

Target: ERK, Trk receptor, Akt

XMD17-109

T1842

Synonym: XMD17 109,ERK5-IN-1

Target: Piezo Channel

ERK1/2 inhibitor 2

T8472

Synonym: ASTX-029,ASTX029

Target: ERK

TBHQ

T5364

Synonym: tert-Butylhydroquinone

Target: Apoptosis, ERK, Others, Ferroptosis, Nrf2, Autophagy

PD98059

T2623

Synonym: PD 98059

Target: ERK, Aryl Hydrocarbon Receptor, MEK, Autophagy

VX-11e

T3166

Synonym: Vertex-11e,VTX-11e,TCS ERK 11e

Target: ERK, GSK-3, FLT, CDK, Aurora Kinase

Ulixertinib

T7005

Synonym: BVD-523,VRT752271

Target: ERK

Lidocaine Hydrochloride hydrate

T1144L

Synonym:

Target: EGFR, Sodium Channel

EF24

T27242

Synonym: EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone

Target: ERK, MEK, Caspase

AG126

T4092

Synonym: Tyrphostin AG126,AG 126

Target: ERK, COX

Lidocaine

T0468

Synonym: Lignocaine,Alphacaine,Xylocaine

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel, Histamine Receptor

SEW2871

T2171

Synonym: SEW2871

Target: S1P Receptor, LPL Receptor

TRPM4 inhibitor 8

T9776

Synonym:

Target: TRP/TRPV Channel

Protein kinase inhibitors 1

Synonym: CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl

Target: ROCK, SGK, Casein Kinase, CDK, S6 Kinase

Cat No.	Product Name	Synonyms	Targets
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.		ERK
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
T1711	Harmine	Telepathine	MAO , 5-HT Receptor , DYRK
	Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.		MAO , 5-HT Receptor , DYRK
T2811	Harmine hydrochloride	telepathine hydrochloride	5-HT Receptor , DYRK , GluR
	Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.		5-HT Receptor , DYRK , GluR
T3856	Tenuifoliside A		ERK , Others
	Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.		ERK , Others
T3857	Magnolin	(+)-Magnolin	ERK
	Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.		ERK
T3844	Deltonin		ERK , Others , Akt , Endogenous Metabolite
	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).		ERK , Others , Akt , Endogenous Metabolite
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
T6947	Piperlongumine	PPLGM,Piplartine	Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy
	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
TN1410	Asperulosidic acid	ASPA	ERK , NF-κB
	Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...		ERK , NF-κB
TL0016	Sulforaphene		Apoptosis , ERK , EGFR , NF-κB
	Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG...		Apoptosis , ERK , EGFR , NF-κB
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
T3876	Loureirin B		PAI-1 , ERK , Potassium Channel , JNK
	Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...		PAI-1 , ERK , Potassium Channel , JNK
T6S0619	Pachymic acid	3-O-Acetyltumulosic acid	ERK , Akt
	Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.		ERK , Akt
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
TMS2181	Trans-Zeatin	(E)-Zeatin	ERK , MEK , Endogenous Metabolite
	trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.		ERK , MEK , Endogenous Metabolite
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
TN1035	Irisolidone		IL Receptor , NF-κB , Chloride channel
	Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.		IL Receptor , NF-κB , Chloride channel
T3908	10-Gingerol		Apoptosis
	10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).		Apoptosis
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...		NF-κB
T2869	Emodin	Frangula emodin	SARS-CoV , Casein Kinase , Autophagy
	Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.		SARS-CoV , Casein Kinase , Autophagy
T3410	Momordin Ic	Momordin 1c	Apoptosis , MAPK , PI3K
	Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. A...		Apoptosis , MAPK , PI3K
TN6735	Bigelovin		Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR
	Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
TN4883	Quinine sulfate dihydrate		Others
	Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...		Others
T6S2227	Spinosin	Flavoayamenin	Others
	1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...		Others
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T4969	Guanosine 5'-triphosphate trisodium salt	GTP Trisodium salt,5'-GTP trisodium salt	Endogenous Metabolite
	Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se...		Endogenous Metabolite
T2915	Bardoxolone	RTA 401,CDDO	Others , Nrf2
	Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...		Others , Nrf2
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T6S1699	Shogaol	[6]-Shogaol,6-Shogaol	Lipoxygenase , Autophagy
	1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...		Lipoxygenase , Autophagy
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T4430	Isosaponarin		Others
	Isosaponarin increases collagen synthesis in human fibroblasts, causes by up-regulated TbetaR-II and P4H production.		Others
T11834	Leelamine hydrochloride		Others
	Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabin...		Others
T11219	Equisetin		Others
	Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence ...		Others

Natural Products

Target: ERK, AMPK, STAT

Harmine

T1711

Synonym: Telepathine

Target: MAO, 5-HT Receptor, DYRK

Harmine hydrochloride

T2811

Synonym: telepathine hydrochloride

Target: 5-HT Receptor, DYRK, GluR

Synonym: (+)-Magnolin

Target: ERK, Others, Akt, Endogenous Metabolite

Epieriocalyxin A

TN3967

Synonym:

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Piperlongumine

T6947

Synonym: PPLGM,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

Target: Apoptosis, ERK, EGFR, NF-κB

Gypenoside L

TN1721

Synonym:

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Loureirin B

T3876

Synonym:

Target: PAI-1, ERK, Potassium Channel, JNK

Pachymic acid

T6S0619

Synonym: 3-O-Acetyltumulosic acid

Target: ERK, NF-κB, COX, PGE Synthase

trans-Zeatin

TMS2181

Synonym: (E)-Zeatin

Target: ERK, MEK, Endogenous Metabolite

Nitidine chloride

T5S0761

Synonym:

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Tauroursodeoxycholate

T2532

Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Pelargonidin chloride

TN1058

Synonym:

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

Irisolidone

TN1035

Synonym:

Target: IL Receptor, NF-κB, Chloride channel

Synonym: Isoverbascoside

Target: NF-κB

Emodin

T2869

Synonym: Frangula emodin

Target: SARS-CoV, Casein Kinase, Autophagy

Momordin Ic

T3410

Synonym: Momordin 1c

Target: Apoptosis, MAPK, PI3K

Bigelovin

TN6735

Synonym:

Target: Apoptosis, Reactive Oxygen Species, Retinoid Receptor, Autophagy, RAR/RXR

Quinine sulfate dihydrate

Synonym: Flavoayamenin

Target: TNF, Tyrosinase, Interleukin

Guanosine 5'-triphosphate trisodium salt

T4969

Synonym: GTP Trisodium salt,5'-GTP trisodium salt

Target: Endogenous Metabolite

Bardoxolone

T2915

Synonym: RTA 401,CDDO

Target: Others, Nrf2

Vitexin

T6S1369

Synonym: Apigenin-8-C-glucoside

Target: Antioxidant

(-)-Bornyl acetate

TN1448

Synonym: L-(-)-Bornyl acetate,Bornyl acetate

Target: p38 MAPK, NF-κB, JNK, Antifungal

Shogaol

T6S1699

Synonym: [6]-Shogaol,6-Shogaol

Target: Lipoxygenase, Autophagy

Sauchinone

T6S1572

Synonym:

Target: ERK, p38 MAPK, NF-κB

Linalool

T2S2264

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Leelamine hydrochloride

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03601	PDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chapero...
TMPY-02029	CDO Protein, Human, Recombinant (His)	Human	HEK293
	Cell adhesion molecule-related, down-regulated by oncogenes (CDON), also known as CDO, is an Ig superfamily member, is a component of a cell surface receptor that positively regulates skeletal myogenesis. Brother of CDO ...
TMPY-01577	ORP150 Protein, Human, Recombinant (His)	Human	HEK293
	Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four differen...
TMPY-03499	CARHSP1 Protein, Human, Recombinant (His)	Human	E. coli
	CARHSP1 is a biomarker for diabetic complications. Adenovirus-mediated CARHSP1 overexpression and siRNA-mediated knockdown experiments were performed to characterize the role of CARHSP1 in the regulation of gluconeogen...
TMPJ-00006	CXCL1 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal ...
TMPY-04561	SGK3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase ...
TMPY-00133	PARM-1 Protein, Human, Recombinant (His)	Human	HEK293

TMPJ-01100	UBE2V1 Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inact...
TMPH-01127	COMMD5 Protein, Human, Recombinant (His)	Human	E. coli
	COMMD5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-03269	COMMD5 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the ...
TMPY-03807	SMR3B Protein, Human, Recombinant (His)	Human	HEK293

TMPY-04380	DYRK3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase...
TMPH-01126	COMMD5 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	COMMD5 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-01116	SMR3B Protein, Human, Recombinant (mFc)	Human	HEK293

TMPY-03046	APCDD1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res...
TMPJ-00935	PDIA3 Protein, Human, Recombinant (His)	Human	Human Cells
	PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones...
TMPH-01210	DENR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes....
TMPJ-01133	NEDD8 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recrui...
TMPJ-01132	NEDD8 Protein, Human, Recombinant	Human	E. coli
	Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recrui...
TMPH-00485	CCL17 Protein, Canine, Recombinant (His & KSI)	Canine	E. coli
	CCL17 Protein, Canine, Recombinant (His & KSI) is expressed in E. coli.
TMPH-00078	Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active...
TMPJ-01312	TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...
TMPY-03443	NDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differ...
TMPJ-00369	PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated	Human	Human Cells
	Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi...
TMPJ-00368	PCSK9 Protein, Human, Recombinant (Avi), Biotinylated	Human	Human Cells
	Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin...
TMPJ-00014	Resistin Protein, Human, Recombinant (His)	Human	E. coli
	Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPH-01029	CAPN1 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His...
TMPH-01031	CAPN2 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cle...
TMPY-02294	Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-05096	Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)	Human	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-03739	Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-01873	Transferrin Receptor/TFRC Protein, Human, Recombinant (His)	Human	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-00392	PAM Protein, Human, Recombinant (His)	Human	HEK293
	Peptidylglycine alpha-amidating monooxygenase (PAM) is highly expressed in neurons and endocrine cells, where it catalyzes one of the final steps in the biosynthesis of bioactive peptides. PAM is also expressed in unicel...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00322	DEC-205 Protein, Human, Recombinant (His)	Human	HEK293
	LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-00369	LY6D Protein, Human, Recombinant (mFc)	Human	HEK293
	LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of...
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-03490	IL-22 Protein, Human, Recombinant	Human	E. coli
	IL22 is a member of a group of cytokines called the IL-1 family of IL-1 superfamily (including IL-19, IL-2, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. It shares the use of IL-1R2 i...
TMPY-04966	PCSK9 Protein, Human, Recombinant (D374Y, His)	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-00408	PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05131	PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05337	CXCL16 Protein, Human, Recombinant (His)	Human	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPY-01630	Syndecan-1 Protein, Human, Recombinant (His)	Human	HEK293
	Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development...
TMPY-01859	LYPD3 Protein, Human, Recombinant (His)	Human	HEK293
	Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 ...
TMPY-02938	REG4 Protein, Rat, Recombinant (His)	Rat	HEK293
	Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be inv...
TMPJ-01210	IL-33 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPY-02707	PAH Protein, Human, Recombinant (415 Asn/Asp, His)	Human	Baculovirus-Insect Cells
	PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-00203	LOXL2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ...
TMPY-01736	COX-2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
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PDRG1 Protein, Human, Recombinant (His)

TMPY-03601

Species: Human

Expression System: E. coli

CDO Protein, Human, Recombinant (His)

TMPY-02029

Species: Human

Expression System: HEK293

ORP150 Protein, Human, Recombinant (His)

TMPY-01577

Species: Human

Expression System: HEK293

CARHSP1 Protein, Human, Recombinant (His)

TMPY-03499

Species: Human

Expression System: E. coli

CXCL1 Protein, Mouse, Recombinant (His)

TMPJ-00006

Species: Mouse

Expression System: Human Cells

SGK3 Protein, Human, Recombinant (His & GST)

TMPY-04561

Species: Human

Expression System: Baculovirus-Insect Cells

PARM-1 Protein, Human, Recombinant (His)

TMPY-00133

Species: Human

Expression System: HEK293

UBE2V1 Protein, Human, Recombinant (His)

TMPJ-01100

Species: Human

Expression System: E. coli

COMMD5 Protein, Human, Recombinant (His)

TMPH-01127

Species: Human

Expression System: E. coli

COMMD5 Protein, Rat, Recombinant (His & Myc)

TMPH-03269

Species: Rat

Expression System: E. coli

SMR3B Protein, Human, Recombinant (His)

TMPY-03807

Species: Human

Expression System: HEK293

DYRK3 Protein, Human, Recombinant (His & GST)

TMPY-04380

Species: Human

Expression System: Baculovirus-Insect Cells

COMMD5 Protein, Human, Recombinant (His & Myc)

TMPH-01126

Species: Human

Expression System: Baculovirus

SMR3B Protein, Human, Recombinant (mFc)

TMPY-01116

Species: Human

Expression System: HEK293

APCDD1 Protein, Human, Recombinant (hFc)

TMPY-03046

Species: Human

Expression System: HEK293

PDIA3 Protein, Human, Recombinant (His)

TMPJ-00935

Species: Human

Expression System: Human Cells

DENR Protein, Human, Recombinant (His & SUMO)

TMPH-01210

Species: Human

Expression System: E. coli

NEDD8 Protein, Human, Recombinant (His & SUMO)

TMPJ-01133

Species: Human

Expression System: E. coli

NEDD8 Protein, Human, Recombinant

TMPJ-01132

Species: Human

Expression System: E. coli

CCL17 Protein, Canine, Recombinant (His & KSI)

TMPH-00485

Species: Canine

Expression System: E. coli

Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00078

Species: Arabidopsis thaliana

Expression System: E. coli

TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)

TMPJ-01312

Species: Mouse

Expression System: Human Cells

NDRG1 Protein, Human, Recombinant (His)

TMPY-03443

Species: Human

Expression System: E. coli

PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated

TMPJ-00369

Species: Human

Expression System: Human Cells

PCSK9 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00368

Species: Human

Expression System: Human Cells

CXCL2 Protein, Mouse, Recombinant

TMPJ-00011

Species: Mouse

Expression System: E. coli

Resistin Protein, Human, Recombinant (His)

TMPJ-00014

Species: Human

Expression System: E. coli

CAPN1 Protein, Human, Recombinant (His)

TMPH-01029

Species: Human

Expression System: E. coli

CAPN2 Protein, Human, Recombinant (His)

TMPH-01031

Species: Human

Expression System: E. coli

Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)

TMPY-02294

Species: Mouse

Expression System: HEK293

Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)

TMPY-05096

Species: Human

Expression System: HEK293

Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-03739

Species: Cynomolgus,Rhesus

Expression System: HEK293

Transferrin Receptor/TFRC Protein, Human, Recombinant (His)

TMPY-01873

Species: Human

Expression System: HEK293

PAM Protein, Human, Recombinant (His)

TMPY-00392

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

TMPY-01936

Species: Mouse

Expression System: HEK293

DEC-205 Protein, Human, Recombinant (His)

TMPY-00322

Species: Human

Expression System: HEK293

LY6D Protein, Human, Recombinant (mFc)

TMPY-00369

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (His)

TMPY-00949

Species: Human

Expression System: HEK293

IL-22 Protein, Human, Recombinant

TMPY-03490

Species: Human

Expression System: E. coli

PCSK9 Protein, Human, Recombinant (D374Y, His)

TMPY-04966

Species: Human

Expression System: HEK293

PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)

TMPY-00408

Species: Human

Expression System: HEK293

PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05131

Species: Human

Expression System: HEK293

CXCL16 Protein, Human, Recombinant (His)

TMPY-05337

Species: Human

Expression System: HEK293

Syndecan-1 Protein, Human, Recombinant (His)

TMPY-01630

Species: Human

Expression System: HEK293

LYPD3 Protein, Human, Recombinant (His)

TMPY-01859

Species: Human

Expression System: HEK293

REG4 Protein, Rat, Recombinant (His)

TMPY-02938

Species: Rat

Expression System: HEK293

IL-33 Protein, Mouse, Recombinant

TMPJ-01210

Species: Mouse

Expression System: E. coli

PAH Protein, Human, Recombinant (415 Asn/Asp, His)

TMPY-02707

Species: Human

Expression System: Baculovirus-Insect Cells

LOXL2 Protein, Mouse, Recombinant (His)

TMPY-00203

Species: Mouse

Expression System: HEK293

COX-2 Protein, Human, Recombinant (His)

TMPY-01736

Species: Human

Expression System: Baculovirus-Insect Cells

--------- More ---------

Cat No.	Product Name
L9000	Apoptosis Compound Library	1796 compounds
	A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
L9700	Endoplasmic Reticulum Stress Compound Library	193 compounds
	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L3200	Autophagy Compound Library	1248 compounds
	A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L8700	Ferroptosis Compound Library	800 compounds
	A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；
L8600	Ubiquitination Compound Library	214 compounds
	A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；
L8110	Reprogramming Compound Library	1840 compounds
	A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L4100	TGF-beta/Smad Compound Library	185 compounds
	A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
L1110	Microtubule-Targeted Compound Library	155 compounds
	A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS;
L2550	Glutamine Metabolism Compound Library	580 compounds
	A unique collection of 580 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...
L9410	Covalent Inhibitor Library	1949 compounds
	A unique collection of 1949 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，acrylamide, ketocarbonyl，disulfide bond, etc.