r-gt

RGT-068A is a potent, selective, and orally bioavailable MALT1 inhibitor.

8-Br-GTP (tetrasodium) [8-Bromoguanosine-5'-triphosphate (tetrasodium)] is a derivative of the energy substrate GTP, utilized in protein synthesis and gluconeogenesis. It inhibits the E. coli GTPase FtsZ with a Ki value of 31.8 μM and promotes the assembly of microtubules in pig brains.

8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification.

γ-GT (H-GLA(PNA)-OH) is used as a synthetic substrate for gamma-glutamyltransferase (GGT) to determine GGT activity.

Arg-AMS is an arginine tRNA synthetase inhibitor with antiviral activity that targets the host protein CD163 to inhibit porcine blue ear virus and the highly pathogenic strain HP-PRRSV, and can be used to study viral infections and myeloma.

Antagonist G is an anticancer peptide and is also a broad spectrum neuropeptide growth factor antagonist.

Antho-rwamide I is an anthozoan neuropeptide.

Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).

2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein , but not by inhibitors of clathrin- or micropinocytosis-mediated endocytosis. It induces cytotoxicity in H1299 cells (IC50 = 92.7 μg/ml).

Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system used3. Other effects of AM include increasing the tolerance of cells to oxidative stress and hypoxic injury and angiogenesis. AM is seen as a positive influence in diseases such as hypertension, myocardial infarction, chronic obstructive pulmonary disease and other cardiovascular diseases, whereas it can be seen as a negative factor in potentiating the potential of cancerous cells to extend their blood supply and cause cell proliferation.

(H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 trifluoroacetate is a useful organic compound for research related to life sciences and the catalog number is T64688.

Boc-β-HoArg(Tos)-OH is an amino acid derivative widely used in life science research.

H-Arg(Tos)-OH, an amino acid derivative, has a wide range of applications in life science-related research.

(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.

ArgTX-48 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.

Argtide is an luteinizing hormone releasing hormone (LHRH) antagonist.

DMJ-I-228 is a specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group.

AZD-3783 is a selective 5-hydroxytryptamine 1B receptor antagonist with probable antidepressant and anxiolytic activity.

ArgTX-93 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.

Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR), a hexapeptide substrate for protein kinase C associated with the EGF receptor, facilitates the determination of enzyme activity [1].

N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor (IC50 = 75 μM) that effectively inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat [1].

WLSEAGPVVTVRALRGTGSW TFA, a cardiomyocyte-specific peptide, exhibits enhanced performance through its expression in exosomes, which notably improves uptake by cardiomyocytes, reduces apoptosis within these cells, and increases cardiac retention after intramyocardial injection in vivo [1] [2].

Adrenocorticotropic Hormone (ACTH) (4-10), human is a potent agonist of the melanocortin receptor (MC4R).

Arg-Trp, a dipeptide consisting of arginine and tryptophan, and its analogues, specifically the octyl ester, exhibit antibacterial activity [1].