quinazoline

Terazosin hydrochloride (Hytrin) , a selective alpha1-antagonist, can treat the benign prostatic hyperplasia (BPH). It also can lower blood pressure, so it is a drug of choice for patients with prostate enlargement and hypertension. It works on the smooth muscle of the bladder and the blood vessel walls by blocking the function of adrenaline.

UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.

UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays.

Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).

Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.

4-CHLORO-QUINAZOLINE, with CAS No. 5190-68-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-CHLORO-QUINAZOLINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.1,2,3,4,5It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.1,2,3It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib , with antiproliferative activity.4,5

(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine is a useful organic compound for research related to life sciences. The catalog number is T66391 and the CAS number is 314771-76-1.

6-Bromo-4-hydroxyquinazoline, with CAS No. 32084-59-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-4-hydroxyquinazoline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Bromoquinazoline-2,4(1H,3H)-Dione (7-Bromo-2,4(1H,3H)-quinazolinedione) is a marine derived natural products found in Pyura sacciformis.

N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride is an inhibitor of TRPC4.

2-CHLORO-4-PHENYLQUINAZOLINE, with CAS No. 29874-83-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-CHLORO-4-PHENYLQUINAZOLINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Fumiquinazoline A is a useful organic compound for research related to life sciences. The catalog number is T125912 and the CAS number is 140715-85-1.

Carnequinazoline A is a useful organic compound for research related to life sciences. The catalog number is T126280 and the CAS number is 1175962-86-3.

Fumiquinazoline D is a fungal metabolite originally isolated from A. fumigatus that has activity against Gram-positive and Gram-negative bacteria (MICs = 8-16 μg/ml) as well as F. solani and C. albicans fungi (MICs = 32 and 64 μg/ml, respectively).

2,4-Dichloro-6,7-dimethoxyquinazoline is a useful organic compound for research related to life sciences. The catalog number is T64861 and the CAS number is 27631-29-4.

2-Chloro-4-amino-6,7-dimethoxyquinazoline is a useful organic compound for research related to life sciences. The catalog number is T65018 and the CAS number is 23680-84-4.

2-(Chloromethyl)-4-methylquinazoline is a useful organic compound for research related to life sciences. The catalog number is T65621 and the CAS number is 109113-72-6.

4-Chloroquinazoline-6,7-diol is a useful organic compound for research related to life sciences. The catalog number is T66020 and the CAS number is 1145671-36-8.

4,6-Dichloro-7-methoxyquinazoline is a useful organic compound for research related to life sciences. The catalog number is T66340 and the CAS number is 205584-69-6.

2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.

6-Nitroquinazoline, an antimalarial agent, is also a substrate for human liver aldehyde oxidase [1].

4-Chloro-6,7-dimethoxyquinazoline is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Selurampanel (BGG492) is an orally active and selective competitive AMPA glutamate receptor antagonist, a quinazoline-dione sulfonamide. selurampanel is used in the study of epilepsy, migraine and tinnitus.